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Saroj Parhate et. al., Preparation and Standarization of Saraswata Churna Prepared by Potentized Method, Int. J. Ayu. Alt. Med., 2015; 3(1):39-42

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RESEARCH ARTICLE eISSN 2348- 0173

Impact Factor (2014) – 0.815 by International Scientific Indexing (ISI) UAE

PREPARATION AND STANDARIZATION OF SARASWATA CHURNA

PREPARED BY POTENTIZED METHOD

Saroj Parhate1*, Prakash H. Khaparde2

1. Associate Professor, Dept. of Rasa-Shastra & Bhaishajya Kalpana, Govt. Ayurved College, Raipur, Chatisgadha. India, Contact No. +918819925299, Email –saroj.parate@yahoo.co.in

2. Dean, Govt. Ayurved College, Osmanabad, Maharashtra - 413501

Article Received on - 13th

Feb 2015

Article Revised on - 24th

Feb 2015

Article Accepted on - 28th

Feb 2015

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Saroj Parhate et. al., Preparation and Standarization of Saraswata Churna Prepared by Potentized Method, Int. J. Ayu. Alt. Med., 2015; 3(1):39-42

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RESEARCH ARTICLE eISSN 2348- 0173

*Corresponding Author

Saroj Parhate Associate Professor, Dept. of Rasa-Shastra & Bhaishajya Kalpana, Govt. Ayurved College, Raipur, Chatisgadha. India, Contact No. +918819925299, Email –saroj.parate@yahoo.co.in

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ABSTRACT: Saraswata Churna is a unique combination of Ayurvedic herbal drugs, containing

mainly those drugs which are having Medhya properties like Vacha, Shankhpushpi,

Ahswagandha, Bramhi etc. For the first time Saraswata churna is described in

Bhavaprakash Unmadadhikar and formula given in the same. Due to its Medhya

properties it is selected for present study. The drug is prepared in the Ayurvedic

Pharmacy of Govt. Ayurved College, Raipur, Chatisgadha. This drug has neurotropic

enhancing property (dhi, dhriti, smriti vardhaka) and works as Medhya rasayana.

This churna (powder) acts in various mental disorders like Unmada (hysteria),

Apasmara (epilepsy), Ardita (facial palsy), Pakshaghata (Paralysis), Anxiety,

Nidranasha (Insomnia) etc.

Key Words: Ayurved, Saraswata Churna, Medhya Rasayana, Manovikara

INTRODUCTION

Ayurveda the science of sukhayu and hitayu and

long life is known for its time tested guidelines for

protecting healthy individual and for preventing

healthy individual from onset of diseases and also

remedy for the diseases. [1] Ayurveda has two aims

i.e. prevention and promotion of health and

secondly cure from the disease.[2] Medha means

intellect and Rasayana means therapeutic

procedure or preparation that on regular practice

will boost nourishment, health, memory, intellect,

immunity and hence longevity. Medhya Rasayanas

are group of medicinal plants described in Ayur-

veda with multi-fold benefits, specifically to

improve memory and intellect by Prabhava

(specific action).[3] Health is the level of

psychological well being and ability to develop

emotionally, psychologically, socially and

spiritually. Like other Ayurvedic drugs of many

potentially effective drugs that acts at various level

in a holistic way to improve the mental ability,

cognition and acts as a good antidepressant. Here

Saraswata Churna is selected for pharmaceutical,

analytical study and effects of the same as Medhya

Rasayana and Manovikara will be discussed.

OBJECTIVE

To prepare and standardize Saraswata Churna

prepared by potentization method

MATERIALS AND METHODS -

Saraswata churna is a unique combination of

herbal drugs containing medhya rasayana drugs

like vacha, shankhapushpi, brahmi and

ashwagandha mentioned firstly in Bhavaprakash

later on in Bhaishajyaratnawali Unmadadhikara

with high quantity of Vacha.[4] In present study

Saraswata churna is prepared in Dept. of

Rasashastra and Bhaishajya kalpana Govt.

Ayurvedic College, Raipur. Chhattisgarh

PHARMACEUTICAL PROCESS –

Preparation of drug (Saraswata Churna)

Name of drug Latin name Part used Quantity

Kuth (Saussurea lappa ) root 25gms

Ashwagandha (Withania somnifera ) Root 25gms

Saindhava lavana (Rock salt ) Mineral 25gms

Ajmoda (Carum roxburghianum ) seed 25gms

Shweta Jiraka (Cuminum cyminum) seed 25gms

Krishna Jiraka (Carum balbocastanum ) seed 25gms

Sunthi (Zingiber officinale ) rhizome 25gms

Pippali (Piper longum) fruit 25gms

Kali Marich (Piper nigrum ) fruit 25gms

Patha (Cissampelos pareira ) Whole plant 25gms

Shankhapushpi (Convolvulus pluricaulis ) Whole plant 25gms

PREPARATION AND STANDARIZATION OF SARASWATA CHURNA

PREPARED BY POTENTIZED METHOD

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Saroj Parhate et. al., Preparation and Standarization of Saraswata Churna Prepared by Potentized Method, Int. J. Ayu. Alt. Med., 2015; 3(1):39-42

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Vacha (Acorus calmus ) rhizome 275gms

Brahmi Bacopa moneri Whole plant juice Q.S.

Three bhavana of brahmi swarasa is given to this

churna and dried in shadow.

Pharmaceutical process to prepare potentized

Saraswata Churna

• 200 g. of prepared Saraswata Churna was

taken in mortar and pestle.

• 25g. of coarse powder of Saraswata churna

was taken and cold infusion method was

prepared in 150ml of water keeping for 12

hours.

• Above Saraswata churna was given bhavana

of prepared cold infusion of this powder.

• By this same procedure 12 bhavanas were

given.

• Dried and preserved in an Air tight container.

Reasoning of Potentization method

• Potency of Churna was increased.

• Efficacy of Churna was increased.

• Produces synergetic effect in drug.

• Particle size of Churna was decreased.

• Absorption rate and Bioavailability was

increased.

• Dose of churna was decreased.

ANALYTICAL STUDY

Table 1 showing results of Physico-chemical tests of Samples of Saraswat Churna

Parameter Sample 1

(as per textual reference)

Sample 2

(potentization method)

Description Yellow color Brown color

Moisture content 12.13 13.35

pH 4.66 6.47

Total ash 14.17 12.21

Acid insoluble ash 1.82 1.42

Water soluble extractives 21.18 17.71

Particle size 2.47 2.96

Sample 1 – Saraswat churna prepared by textual reference

Sample 2 - Saraswat churna prepared by potentisation method.

Table 2 showing dosha karma & prabhava of Saraswata Churna

Drug Rasa Virya Vipaka Dosha

karma Prabhava

Kuth (Saussurea lappa)

Tikta,

madhur,

katu

Ushna Katu Kapha-vata shamaka raktashodhaka

Ashwagandha (Withania

somnifera)

Tikta,

madhur,

katu

Ushna Madhur Kapha-vata shamaka

Raktabharshamaka,

Rasayana

Saindhava lavana (Rock

salt) Lavana Ushna Katu

Vata shamaka

Kapha-pitta

vardhaka

Deepana, Rochana,

Chaksushya, Hridya

Ajmoda (Carum

roxburghianum) Katu -tikta Ushna Katu

Kapha-vata shamaka,

pittavardhaka Deepana

Shweta jiraka (Cuminum

cyminum) Katu Ushna Katu Kapha-vata shamaka Deepana pachana

Krishna jiraka (Carum

balbocastanum) Katu Ushna Katu

Kapha-vata shamaka,

pittavardhaka Deepana pachana

Shunthi (Zingiber

officinale) Katu Ushna Madhur

Kapha-vata shamaka

pittavardhaka

Nadi uttejaka, Hridya,

Raktavaha strotasa uttejaka

Pippali (Piper longum) Katu Anushna

sheet Katu

Kapha-vata shamaka,

pittavardhaka Deepana , Medhya

Marich (Piper nigrum) Katu Ushna Katu Kapha-vata shamaka,

pittavardhaka

Deepana , Uttejaka, Pachana,

Balya

Patha (Cissampelos

pareira) Tikta Ushna Katu

Kapha- pitta

shamaka

Deepana, Pachana,

Raktashodhaka

Shankhapushpi

(Convolvulus pluricaulis ) Tikta Sheet Madhur Vata-pitta shamaka

Medhya, Nidrajanana

Vaccha (Acorus calmus ) Katu Ushna Katu Kapha-vata shamaka,

pittavardhak

Medhya ,

Sangyasthapana,

Akshepashaman

Brahmi (Bacopa

monnieri) Tikta Ushna Katu

Kapha-vata shamaka

Medhya, Akshepahara,

Raktashodhaka

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• pH of sample 1 was strong acidic it will produce

pitta saraka, pitta prakopak, rakta prakopak,

and daha after giving for longer time but it

activates nerve cells. Sample 2 was weak acidic

almost neutral will be Madhur vipaki and will

give nutrition to brain cell and can be given for

longer time.

• Water soluble extractive of sample 1 was more,

so anupana like jala and yusha may be used for

better absorption. Sample 2 was less, must be

taken in lipid media that was milk, ghrita, for

fast absorption.

• Acid insoluble ash of sample 1 was more, that

activates nerve cells can be used in paralysis

extra. In sample 2 was less, gives nutrition to

nerve cells can be used as brain tonic and in

degenerative changes.

DISCUSSION

• Most of the drugs are katu, tikta rasatmaka,

usna virya and katu vipaki. Action of katu rasa

is shoshan and tikta rasa acts as kapha and

amanashaka hence shrotoshodhan kriya is

done. Ushna virya dravyas stimulates and acts

as vasodilators and promotes blood

circulation to brain and whole body. Katu

vipaki acts as kapha and mala nasaka,

tamogunanashaka, and satva guna vardhaka

(buddhi vardhaka) and stimulates nerve

receptors. Some are madhur vipaki and give

nutrition to brain (medhya).

• Medhya rasayana drugs - Vacha,

Shankhapushpi, Ashwagandha and Brahmi.

• Vacha: Medhya Rasayana, enhance Grahana

and Smarana shakti (grasping power and

memory), used in Epilepsy and

Psychoneurosis.

• Shankhapushpi: Medhya, Brain tonic,

Tranquilizer, nervine disorder, mental

aberration, anxiety, enhance neuropeptide

synthesis of brain.

• Ashwagandha: Reduce stress and anxiety,

promotes neuro regeneration. It is sedative,

extract of root exhibit hypotensive,

bradycardiac, depressant action and able to

reconstruct neuronal networks.

• Brahmi: Medhya, promotes Dharana karma

(Retention and Cognition), anxiolytic and

retart brain aeging, sedative, nervine tonic,

antianxiety, used in Psychic disorders.

• Rasayana that acts on agni – Marich, Pippali,

Ajmoda, Shewetajiraka, Krishnajiraka and

Sunthi

• Drugs that spread active principles i.e.

Saindhava lavana along with Raktashodhaka

dravya like Kuth and Patha.

By this pharmaceutical process potency of drug is

increased to give better results than prepared by

text method. Analytically pH, Acid Insoluble Ash

and Water Soluble Extractive is done to correlate

sample 1 and 2.

Saraswata churna with Goghrita and Honey

specially works in 4 different levels i.e. level of

Agni, level of Doshas, level of Manas (mind) and

level of Manovaha strotasa which are finally able to

degrade the samprapti of diseases and resemble

effect as Medhya rasayana.

CONCLUSION

Saraswata churna is established Ayurvedic

formulation which is potentized by giving bhavana

of Saraswata hima. By this process Potency,

Efficacy, Bioavailability is increased & dose is

decreased. This drug has neurotropic enhancing

property (dhi, dhriti, smriti vardhaka) and works as

Medhya rasayana. This churna acts in various

mental disorders like Unmada (hysteria),

Apasmara (epilepsy), Ardita (facial palsy),

Pakshaghata (Paralysis), Anxiety, Nidranasha

(Insomnia) etc. Scientific & experimental studies

conducted in recent years with this class of drugs

have given evidence of neuro nutrient effect,

neural metabolic effect & improve blood perfusion

to the brain and mostly responsible for clinical

effects.

REFERENCES 1. Vagbhata, Ashtanga Hridaya, with Vidyotini Hindi

commentary of Kaviraj Atrideva Gupta, Chaukhambha

Prakashan, Varanasi 2009. p.3

2. Ibid p.4

3. Agnivesha, “Charak Samhita”, with Charak Chandrika

Hindi commentary, by Dr. Brahmanand Tripathi and Dr.

Ganga Sahay Pandey, Chaukhamba Surbharti Prakashan,

2007. p.48

4. Das Govinda. Bhaishajya Ratnavali, edited & enlarged by

Bhisagaratna Shri Brahmashankar Mishra “Vidyotini”

Hindi commentary, 18th ed., Varanasi, India: Chaukhamba

Sanskrit Bhavan, 2005. p.51

.

CITE THIS ARTICLE AS –

Saroj Parhate et. al., Preparation and Standarization of Saraswata Churna Prepared by Potentized Method, Int. J.

Ayu. Alt. Med., 2015; 3(1):39-42

Source of Support – Nil Conflict of Interest – None Declared

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