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Page 1: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Kupipakwa rasayana

Dr Raghuveer Dept of Rasashastra

KVG Ayurvedic Medical College Sullia

[email protected]

Page 2: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Rasavaidya shresthata

• UTTAMO RASAVAIDYASTU MADHYAMO

MOOLIKADIBHI: SHASTRASTADHAMAHA…..

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Page 3: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Chaturvidha rasayana

• KHARALIYA RASAYANA

• PARPATI RASAYANA

• POTTALI RASAYANA

• KUPIPAKWA RASAYANA

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Page 4: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

KUPI PAKWA RASAYANA

• ALPAMAATROPAYOGITWAT

ARUCHERAPRASANGATAH |

KSHIPRAMAAROGYADAAYITWAT

OUSHADHEBHYO ADHIKO RASA||

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Page 5: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

HISTORY

• 12th century AD onwards

• Sri Dundukanatha – Rasendra chintamani

• Best example of Murchana

• Agni- Kramaagni

• Valuka Yantra

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Page 6: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Contd…

• Ancient Indian alchemists were expert in transforming lower metals to

higher metals. In this way ancient scholars were used to potentiate and transform

mercury to certain higher level metals by different Jarana procedures. In Jarana

process, Gandhaka was commonly used for this purpose. Different proportion of

Gandhaka was used to mix with Parada and gradually potentiate the preparation

of Parada. In such experimentation of Jarana, the use of Kupipakva method was

adopted.

• It is believed that the cause for the invention of Kupipakva method might be

certain special procedures done on Parada and Gandhaka and also the

temperature is particularly controlled to get the desired effect in the final product.

Such procedures of Gandhaka Jarana have firstly been mentioned by Acharya

Govinda Bhagvat Pada in his treatise.

• In 8th century A.D. Govinda Bhagavatpada described Gandhaka Jarana vidhi

in Rasa Hridaya Tantra. Sri Dundukanatha, the author of Rasendra Chintamani

was the first person to introduce Kupipakwa Rasayana preparations in the

Ayurvedic therapeutics during 12th century A.D.

Kupipakwa Rasayana 6

Page 7: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Contd…

• In Rasendra Chintamani there is clear cut reference about specific

heating pattern named as Kramagni paka i.e. increasing manner of

heat (Mrudu, Madhya and Tivragni), with intermediate heating for

a specific period has been mentioned. The same method is used in

practice now a days with some modifications.

• Kupipakva Rasayana was developed by Siddha Sampradaya i.e.

from 13th century. Acharya Yoshodhara Bhat (13th cent.) in his text

Rasa Prakash Sudhakar quoted Sindhura Kalpana by the name of

Udayabhaskar Rasa.

• Udaya Bhaskara rasa is nothing but the name of Rasasindura. At

the same place, he has given the method of Rasakarpura

preparation by the name "Ghanasara-Rasa". He has used

Kachaghati (Kupi) Sikatayantra for the preparation of

Udayabhaskar Rasa (Rasa Prakash Sudhakar 3/10- 14).

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Page 8: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Contd… • In Anandakanda, Manthana Bhairava writes about the

same procedure under the heading of Rasa Murcchana vidhi. In 13th century A.D, Rasa Vagbhata, the author of Rasa Ratna Samucchaya mentioned some preparations by combining Parada with Gandhaka such as Agnikumara Rasa.

• The classics of 15th, 16th, 17th century explained Kupipakwa Rasayana in the name of Sindhura Rasa or Sindhura Sadrisha Rasa.

• In 15th century, Anantdev Suri in his text Rasa Chintamani described “Rasaparthiva Rasa".

• Overall after critical study, one can come to conclusion that process of Gandhaka Jarana mentioned in Rasa Hridaya Tantra, developed and came inlight as Kupipakva Rasayana. Kupi Pakva Rasayana Kalpana is also known as Sindhura Kalpana. Kupipakwa Rasayana 8

Page 9: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Derivation

• KUPI ITI KACHA KUPI

• PAKWAM ITI AGNINA PAKWAM

• RASASYA PARADASYA

• AYANAM STHANAM ARTHAT

• KUPYAM AGNINAM PAKWAM

YADRASAAYANAM TAT KUPI PAKWA

RASAYANAM

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Page 10: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

SPECIFIC FEATURES

• Specialized heating pattern

• Valuka yantra

• Indirect constant heat

• Dose

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Page 11: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Classification

• 256 kupi pakwa rasayanas mentioned by Sri

Harisharanananda in his grantha kupi-pakwa

vijnaniyam

Classified as follows-

• Mercury + sulphur

• Mercury + sulphur + metals

• Mercury + sulphur + non-metals

• Mercury + sulphur + metals + non-metals

• Mercury + other compounds

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Page 12: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Kupipakwa Rasayana 12

Ingredients

Sagandha Prepared with the use of Gandhaka e.g. Vyadhiharana Rasa

Makaradhwaja, ManikyaRasa, Rasa sindhura.

Nirgandha Prepared without the use of Gandhak e.g. Rasakarpura, Rasa

Pushpa

Manufacturing

method

Antardhuma is applied in the beginning and the vapors are not allowed to

escape e.g. Rasasindhura.

Bahirdhuma is applied after burning of sulphur e.g. Vyadhiharana Rasa,

Hinguliya Manikya Rasa, Sila sindhura.

Place of finished

product

Kanthastha The finished product is deposited at the neck e.g.

Makaradhwaja, Rasa sindhura

Talastha The product is obtained from the bottom of the Kupi e.g.

Sameerapannaga-Rasa, Swarna Vanga.

Ubhayastha Final products obtained from both the sites e.g.

Sameerapannaga Rasa, Hinguliya Manikya Rasa.

Page 13: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Kanthastha/galastha

Talastha

Ubhayastha

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Page 14: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Method

1 • Poorva karma

2 • Pradhana karma

3 • Paschat karma

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Page 15: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Poorva karma

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Page 16: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

• Collection of necessary instruments

• Shodhana

• Kajjali

• Preparation of kupi

• Filling of kajjali to kupi

• Placing kupi in valuka yantra

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Page 17: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Collection of necessary instruments

• Musha / kupi

• Vastra (cotton cloth)

• Multani mrittika

• Valuka yantra/EMF

• Valuka

• Shalaka

• Copper coin

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Page 18: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Shodhana

• Raw materials identified first and then

subjected to shodhana as per the ref….

• Samyak shuddhi lakshanas obseved

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Page 19: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Preparation of Kajjali

• Slakshnatwa

• Kajjalabhasa

• Nishchandratwa

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Page 20: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Preparation of Kupi

• Selection of bottle

• Wrapping glass bottle with mud smeared cloth

• As per classic 7 layers

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Page 21: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Filling of kajjali to kupi

• Fill 1/3rd part so that there should be free space

inside kupi for melting and boiling of kajjali

• Also for sublimation of compound which is

going to condensed and deposited in neck part

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Page 22: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Placing kupi

• Placed at the centre part of the valuka yantra

so that to get uniform temperature

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Page 23: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Pradhana karma

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Page 24: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

• Heating schedule

• Temperature recording

• Shalaka sanchalana

• Observation of fumes and flame

• Corking of kupi mouth

• Swangasheeta

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Page 25: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

BMK Ayurveda Mahavidyalaya Belgaum

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Page 26: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

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Page 27: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Valuka yantra

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Page 28: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Baidyanath Pharma Alahabad

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Page 29: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Ipgtra jamnagar

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Page 30: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

EMF (Electric Muffle Furnace)

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Page 31: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Heating schedule

• Kramagni

Mrudu agni

Madhyama agni

Teevra agni

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Page 32: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Temperature

• Ancient method- cotton/dried husk test

• Modern method:

Thermometer/Pyrometer/Thermocouple

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Page 33: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Shalaka sanchalana

• Tapta shalaka- to burn extra sulphur deposited

as neck part of kupi

• Sheeta shalaka- to know the state of kajjali i.e.

powder form / melted / boiling / sublimation

stage of product

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Page 34: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Shalaka sanchalana

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Page 35: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Observation of fumes and flame

• Fumes – colour, odour,

Differs acc to ingredients

Yellow / orrange / bluish / white

Odour like sulphur / arsenic

• Flames – timing of appearance of flame, its

colour and duration noted

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Page 36: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Observation of fumes/flames

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Page 37: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Corking of kupi

Before corking Observe for-

• Absence of fumes and flames

• Copper coin test

• Sheeta shalaka test

• Appearance of redness at the bottom of kupi

• Adherence of golden particles

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Page 38: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Copper coin test

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Page 39: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Paschat karma

Kupipakwa Rasayana 39

Page 40: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

• Removal of kupi from valuka yantra

• Breaking of kupi

• Collection of product

• Examination of product

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Page 41: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Removal of kupi

• Care should be taken – sometimes kupi may

break

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Page 42: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Breaking of kupi

• Traditional method

• Scrap and remove the layers of kupi

• A thread soaked in spirit should be tied around

the middle of kupi and ignited

• Kept horizontally, rotate the kupi to burn

thread

• Then wrap with wet cloth

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Page 43: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Breaking of Kupi

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Page 44: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Collection of product

Kanthasta / Talastha/ Ubhayastha

• Rasasindhur, Malla sindhur – kanthastha

• Swarna vanga – talasta

• Makaradhwaja, hinguliya manikya rasa- Ubhayastha

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Page 45: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Collection of Swarna vanga

(Talastha)

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Page 46: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Collection of Kanthasta material

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Page 47: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

Examination of product

Physical / organoleptic examination:

• Colour, odour, consistancy, shiny, soft, crystalline, amorphous etc

Chemical examination:

• Qualitative / Quantitative

Instrumental examination:

• XRD/XRF/IR/UV/ ICPMS/ TEM/ AAS/flame photomter etc

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Page 48: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

IMPORTANCE OF KUPIPAKWA RASAYANA

• Kupipakva Rasayana Kalpana is having importance among other

Kalpanas because of having following properties:

(1) Potency of these drugs remains for longer period.

(2) It requires minimal dose.

(3) Easy for administration.

(4) More potent as compared to other pure herbal preparations.

(5) When mixed with other drugs, it reduces the dose of other drugs.

(6) Due to its quicker action.

(7) Chemical bond becomes stronger in the following order; Kajjali,

Parpati, Pottali and Kupipakva Rasayana.

Kupipakwa Rasayana 48

Page 49: Kupipakwa rasayana - IAMJ · •Sri Dundukanatha – Rasendra chintamani •Best example of Murchana •Agni- Kramaagni •Valuka Yantra Kupipakwa Rasayana 5

SIDDHE RASE KARISHYAMI

NIRDARIDYAMAYAM JAGAT

Kupipakwa Rasayana 49


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