presentation 2013-04-03 dr suresh

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  • 7/28/2019 Presentation 2013-04-03 DR SURESH

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    SNAKE BITE

    Dr.B.Sureshkumar

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    Presented with Snake bite to L/s ankle 1hour back

    Snake identified as Viper

    PMHxMental retarded pt

    Examination

    BP-110/70 mmHg PR- 80/min

    Lungsclear Abdomensoft

    No ptosis, No opthalmoplegia, No bleeding manifestations

    LocalNo swelling, No fang marks.

    Mr. Mohan

    30 years

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    IX

    Whole blood clotting time < 20min on admission Rx

    IM tetanus toxoid 0.5mg stat

    WBCT in 2hours

    KUO for ptosis, Bleeding manifestations

    Monitor UOP, BP, RR

    After 2 Hours of Admission. Pt developed Ptosis

    WBCT >20min RxIV Anti-venom Serum 10 vials given

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    Day 2

    8 hours later

    WBCT > 20min

    B/L ptosis

    BP-75/60 mmHg Hyperthermia+

    Ix-

    CBS171 mg/dl

    Rx-

    IV AVS 5 vials stat (2nd

    Dose)

    IV Dopamine 5g/Kg/min started and

    titrated according to BP

    IV Cloxacillin 500mg

    6hrly IV Hydrocortisone

    400mg stat

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    Day 3

    Loose stools

    Bp- 100/70 mmHg

    80/50mmHg ECGST in Inferior

    leads

    Fever+

    S. Cr1.6

    Rx

    IV Metronidazole 500mg

    8hrly

    IV Ciprofloxacin 400mgBD

    IV Dobutamine 10

    g/Kg/min

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    Day 4

    BP100/70mmHg

    HR110/ Min

    RespB/L crepts

    SpO2

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    At TH-Batticaloa

    Pt went into respiratory failure and Intubated.

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    Signs and Symptoms of

    Envenomation.

    Symptoms:

    Local pain at bite site80%

    Pain in regional lymph nodes55%

    Vomiting26%

    Bleeding from distant sites24%

    Drowsiness14%

    Epigastric pain8% Lower back pain7%

    Dizziness/impaired consciousness2%

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    Signs

    Local

    Local swelling 68%

    Tender, enlarged lymphnodes 54%

    Bleeding at bite site 31%

    Local blistering andnecrosis 2%

    Systemic envenomation

    Spontaneous

    systemic

    bleeding46%Hypotension35%

    Conjunctival

    edema24%

    Bleeding from

    gums20%

    Bleeding from

    venipuncture

    sites15%

    Hematemesis11%

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    Urinary Symptoms and Renal

    Failure

    Hematuria 72%

    BUN range 14 - 68%

    Proteinuria (>1 gm/liter) 55% RBC casts55%

    Oliguria 44%

    Renal-angle tenderness 39%

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    Indication for Anti venom.

    Incoagulable blood with 20 mins of WBCT.

    Systemic envenomation.

    Spontaneous bleeding. Neurotoxicity (Russels viper).

    Impaired LOC.

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    WBCT

    Few ml of blood in clean glass tube.

    Leave it for 20 mins undisturbed.

    Do it before and after the administration AVS. Can be repeated in 6 hours time until become

    normal (< 20 min) WBCT.

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    AVS Administration

    1 Vial AVS dissolve in 10 ml of water for

    injection.

    Add 100 ml of N/S.

    Total 200 ml over one hour infusion.

    Watch for reaction.

    Children also should be given same dose.

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    RESPONSE TO AVS

    Hypotension & Bradycardia will improve in

    10-20 mins.

    Spontaneous systemic bleeding stops in 15

    30 mins.

    CNS effects will improve in 30 mins

    Blood coagualability is restored about 6 hours.

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    THANK YOU