rheumatoid arthritis

• 1. 1|P ag e - (Autoimmune) ( Inflammed) , - (Connective Tissue) ( ) , , - , , (- - , ) 1 % , 35 50 , (Juvenile Idiopathic Arthritis) , - (Autoimmune Disease) (Synovial Membrane) , , , , , - , -

2. 2|P ag e , , , , , , , , , (Dislocation) , (Cyst) , 30% ( ) , , , , , , ( Plura) ( Pericardium) , , , , , , , , , , 3. 3|P ag e , - (Juxta-articular Osteopenia), (Subluxation) ... , ... 10 9 ... , ... , 70 % , 96% -(anti-CCP) ( - ) - ( TLC) ... , 4. 4|P ag e ( ) (Felty's syndrome) 10 80% 3-7 , , , 75% 10 % , 20 ... Anti-CCP , (DMARDs) , - , - - - ( NSAIDs), (DMARDs), , , (an interleukin-1 receptor antagonist), 5. 5|P ag e- (NSAIDs) , , NSAIDs 2 NSAIDs (COX) COX-1 , ( ( Mucosa) ) COX-2 COX-2 ( ) - NSAIDs NSAIDs , , ( Confusion), , , (Platelets) DMARDs , , , - 34 , 2% , 24 9 3 1-2 12 6. 6|P ag e ... 6 .... .... , ( Folate Antagonist) (Immunosuppressive) ( 3 4 ) 1 , 8 ..., ...., ...., , , , () DMARDs DMARDs - TNF- antagonists - - , , - ( , ) 7. 7|P ag e (DMARDs) . , , 400-600 (Hydroxychloroquine) HCQS 4-12 200-400 (Leflunomide)20 / , Tab Cleft 10, 20 mg 10 / 7.5 , -(Methotrexate) 25 Tab Folitrax 2.5, 5. 7.5,20 / 10, 15 mg (SC) , , , , Amp - 15 mg / ml (Sulfasalazine) Tab Saaz DS 0.5 1 , 2 3 , , , , (Corticosteroids) (Prednisone)5-60 , , , (Osteoporosis)Tab Wysolone, AzathioprineCyclophosphamide1 / (50100 ) , , , 6-8 0.5 // 4 2.5 , // 23 / .. 8. 8|P ag e: 0.75 /2 ( 1 /2/ 6 ... 3000/L ), 30-60 - .. 50 , 1.75 /(Cyclosporine) 750 .. , , ..., , 2 , 4 4 , (Abatacept) Inj Orencia 250 mg 1 .. , 2 , 4 4 , , , , , (Rituximab)IL-1 (Anakinra)100 , (SC) - (Adalimumab) (Etanercept) (Infliximab)40 (SC) 1 2 ( ..) , , 25 50 , , 3 / .. 2 6 8 ( 10 ) 9. 9|P ag e- (NSAIDs) (Aceclofenac) Altraday, Cap Ace-proxyvon, Erinac-P, (Flupirtine) Cap Snepdol 100 (Etodolac) Tab Toldin ER 600 Fenoprofen) Tab Fenopron 300, 600 (Flurbiprofen) Tab Proben 50, 100 (Indomethacin) Indocap SR 75 (Ketoprofen) Ketofen 50 100 (Nabumetone) Tab Nabuflam 500 Tab Relifex 500 (Naproxen) Tab Naxdom 250, 500 (Oxaprozin) Caplet Daypro 600 (Piroxicam) Cap Dolonex 20 (Sulindac) Clindac 200 (Tolmetin) (Celecoxib) Orthocel 100, 200 (Meloxicam) Mel-one 7.5, 15 75 .. 50 .. 150 , 100 .. 100 .. 100 .. 300500 1200 300600 3200 100 300 25 , 75 200 5075 , 200 300 10002000 2000 250500 1500 1200 1800 20 20 150200 400 400 200 1800 400 7.5 15 10. 10 | P a g e