dksm iqflrdk dksm a 2016 (ii) h tkho fokku 1. जब उनि५ म८ट॥ई बढॳ,...

vuqns’k

1. vkius fgUnh dks ek/;e pquk gS A bl ijh{kk iqfLrdk esa ,d lkS iSarkyhl (20 Hkkx 'A'esa + 50 Hkkx 'B' + 75 Hkkx 'C' esa ) cgqy fodYi iz’u (MCQ)fn, x, gSa A vkidks Hkkx 'A' esa ls vf/kdre 15 vkSj Hkkx 'B' esa 35 iz’uksa rFkk Hkkx 'C' esa Lks 25 iz’uksa ds mRrj nsus gSa A ;fn fu/kkZfjr Lks vf/kd iz’uksa ds mRrj fn, x, rks dsoy Hkkx 'A' Lks 15,Hkkx 'B' ls 35 rFkk Hkkx 'C' ls 25 igys mRrjksa dh tkap dh tk,xh A

2. vksñ,eñvkjñ mRrj i=d vyx Lks fn;k x;k gS A viuk jksy uEcj vkSj dsUnz dk uke fy[kus Lks igys ;g tkap yhft, fd iqfLrdk esa i`”B iwjs vkSj lgh gSa rFkk dgha Lks dVs&QVs ugha gSa A ;fn ,slk gS rks vki bfUothysVj Lks mlh dksM dh iqfLrdk cnyus dk fuosnu dj ldrs gSa A blh rjg Lks vksñ,eñvkjñ mRrj i=d dks Hkh tkap ysa A bl iqfLrdk esa jQ dke djus ds fy, vfrfjDr iUus layXu gSa A

3. vksñ,eñvkjñ mRrj i=d ds i`”B 1 esa fn, x, LFkku ij viuk jksy uEcj] uke rFkk bl ijh{kk iqfLrdk dk Øekad fyf[k,] lkFk gh viuk gLrk{kj Hkh vo'; djsa A

4. vki viuh vksñ,eñvkjñ mRrj i=d esa jksy uacj] fo”k; dksM] iqfLrdk dksM vkSj dsUnz dksM ls lacaf/kr leqfpr orksa dks dkys ckWy isu ls vo’; dkyk djsaA ;g ,d ek= ijh{kkFkhZ dh ftEesnkjh gS fd og vksñ,eñvkjñ mRrj i=d esa fn, x, funsZ’kksa dk iwjh lko/kkuh ls ikyu djsa] ,slk u djus ij dEI;wVj fooj.kksa dk lgh rjhds Lks vdwfVr ugha dj ik,xk] ftlls varr% vkidks gkfu] ftlesa vkidh vksñ,eñvkjñ mRrj i=d dh vLohdfr Hkh ‘kkfey gS] gks ldrh gS A

5. Hkkx 'A' rFkk Hkkx 'B' esa izR;sd iz’u ds 2 vad 'C' esa izR;sd iz’u 4 vad dk gS A izR;sd xyr mRrj dk _.kkRed ewY;kad 25 % dh nj ls fd;k tk,xk A

6. izR;sd iz’u ds uhps pkj fodYi fn, x, gSa A buesa Lks dsoy ,d fodYi gh Þlghß vFkok ÞloksZRre gyß gS A vkidks izR;sd iz’u dk lgh vFkok loksZRre gy <wa<uk gS A

7. udy djrs gq, ;k vuqfpr rjhdksa dk iz;ksx djrs gq, ik, tkus okys ijh{kkfFkZ;ksa dk bl vkSj vU; Hkkoh ijh{kkvksa ds fy, v;ksX; Bgjk;k tk ldrk gS A

8. ijh{kkFkhZ dks mRrj ;k jQ iUuksa ds vfrfjDr dgha vkSj dqN Hkh ugha fy[kuk pkfg, A 9. dsydwysVj dk mi;ksx djus dh vuqefr ugha gS A 10. ijh{kk lekfIr ij fNnz fcUnq fpfUgr LFkku ls OMR mRrj i=d dks foHkkftr djsaA bfUothysVj dks ewy

OMR mRrj i=d lkSaius ds i’pkr vki bldh dkWcZuySl izfrfyfi ys tk ldrs gSaA 11. fgUnh ek/;[email protected] ds iz’u e sa folaxfr gksus@ik;s tkus ij vaxzsth laLdj.k izekf.kd gksxk A

12. dsoy ijh{kk dh iwjh vof/k rd cSBus okys ijh{kkFkhZ dks gh ijh{kk iqfLrdk lkFk ys tkus dh vuqefr nh tk,xh A

H

Øekad

Ikw.kkZad : 200 vad Lke; : 3:00 ?kaVs

3 A fo”k; dksM iqfLrdk dksM

ijh{kkFkhZ }kjk Hkjh xbZ tkudkjh dks eSa lR;kfir djrk gw¡

………………………… bfUothysVj ds gLrk{kj

jksy uacj :…………………………..

uke :...........................................

2016 (II)

Tkho foKku iz’u i=

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FOR ROUGH WORK

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Hkkx \PART 'A'

1. ि ा Q िॳ मापन सबतधि uाजछिि अादविuा रमा: 10% ि ा 2% ह। P/Q म रतिाि uाजछिि अादवि कििनी हॴ?

1. 12.0 2. 9.8 3. 8.0 4. 10.2 1. The random errors associated with the

measurement of and Q are 10% and 2%, respectively. What is the percentage random error in P/Q?

1. 12.0 2. 9.8 3. 8.0 4. 10.2 2. कििनॳ गोचर िरीि म ाद CHANCE िॳ अषर

िो uवजस ि किuा जा सििा हॴ? 1. 120 2. 720 3. 360 4. 240 2. In how many distinguishable ways can the

letters of the word CHANCE be arranged? 1. 120 2. 720 3. 360 4. 240 3. लापिा रतिमान िो ञाि िीजजuॳ?

3. Find out the missing pattern.

4. बीज िो पानी म भभगोनॳ पर उनिॳ भार म 20%

व आuिन म 10% िी ववि होिी हॴ। बीज िा घन व कििनॳ गदणाि सॳ बढॳगा?

1. 1.20 2. 1.10 3. 1.11 4. 1.09 4. Seeds when soaked in water gain about 20%

by weight and 10% by volume. By what factor does the density increase?

1. 1.20 2. 1.10 3. 1.11 4. 1.09 5. एि गतिमान गद पर लगनॳ वाला अवरोधि घाण

बल गद िॳ वॳग , िॳ समानदपािी हॴ। दो एि पी गद दो एि पी ढलान (A ि ा B) पर अलग ऊचाईu सॳ लदढििी ह। गद िॳ अवरोधि बल व वॳग िी िदलना ढलान िॳ िल पर िीजजuॳ?

1. 2. 3. 4. 5. Retarding frictional force, on a moving

ball, is proportional to its velocity, . Two identical balls roll down identical slopes (A & B) from different heights. Compare the retarding forces and the velocities of the balls at the bases of the slopes.

1.

2.

3.

4.

06. किसी एि रजाति िॳ दो तिलचट ह, जजनिी

मोटाई बराबर ह, कि िद लब बाई ि ा चााई अलग-अलग ह। ऑजससजन िी िमी वालॳ वािावरण म जीववि रहनॳ िी षमिा पर रतििल असर िब पाॳगा?

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1. जब उनिी मोटाई बढॳ, लॳकिन उनिॳ बािी माप जॴसॳ िॳ िॴसॳ रह।

2. जब उनिी मोटाई जॴसी िी वॴसी रहॳ, लॳकिन लबाई बढॳ।

3. जब उनिी मोटाई जॴसी िी वॴसी रहॳ, लॳकिन चााई घटॳ।

4. जब उनिी मोटाई घटॳ, लॳकिन उनिॳ बािी माप जॴसॳ िॳ िॴसॳ रह।

6. Two cockroaches of the same species have

the same thickness but different lengths and widths. Their ability to survive in oxygen deficient environments will be compromised if

1. their thickness increases, and the rest of the size remains the same.

2. their thickness remains unchanged, but their length increases.

3. their thickness remains unchanged, but their width decreases.

4. their thickness decreases, but the rest of the size remains unchanged.

7. रा u ववधान सभा चदनाव म चार राजनॴतिि दल

वारा जीिी गई सीट िो स िभ तचम म दाााuा गuा हॴ।

नीचॳ ददuॳ गuॳ पाई-तचम म सॳ िन-सा इस

जानिारी िो सही दााािा हॴ?

7. The bar chart shows number of seats won by

four political parties in a state legislative assembly.

Which of the following pie-charts correctly depicts this information?

8. तनजालीिरण सॳ पीडाि 12 किलोराम िॳ बछ चॳ िो

एि घटॳ म 20 भम.रा. रव रति कि.रा. वन िी, खदराि िॳ प म अि:भारा रव वारा चढuा जाना हॴ। अि:भारा रव िी टपिनॳ िी दर (बद/भमनट) स uा होनी चादहए? (1 भम.रा. = 20 बद)

1. 7 2. 80 3. 120 4. 4 8. Intravenous (IV) fluid has to be administered

to a child of 12 kg with dehydration, at a dose of 20 mg of fluid per kg of body weight, in 1 hour. What should be the drip rate (in drops/min) of IV fluid? (1mg = 20 drops)

1. 7 2. 80 3. 120 4. 4 9. किसी ऊची िि वालॳ महल िी फाा पर लॳटा हदआ

uजसि उसिी िि िो तनहार रहा हॴ। इस महल िी िि एि पी स िभ िॳ रम सॳ दटिी हॴ जो कि उस uजसि िो समािर ददखाई दॳिी हॴ। तनब न म िो िन-सी स िभ आितिuा इसिॳ अनदप ह?

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9. A hall with a high roof is supported by an

array of identical columns such that, to a person lying on the floor and looking at the ceiling, the columns appear parallel to each other. Which of the following designs conforms to this?

10. तनब न म सॳ िन-सा राफ एि सरल रॳखा म

गतिमान वस िद िी गति व उसिॳ अनदप िu िी गई दरी िो सही प सॳ दााािा हॴ?

10. Which of the following graphs correctly shows the speed and the corresponding distance covered by an object moving along a straight line?

11. एि साधारण TV स रीन िी चााई व ऊचाई िा

अनदपाि 4:3 हॴ। जबकि एि हाई डॳकफनी न TV म uह अनदपाि 16:9 हॴ। uदद दोन TV स रीन िी ऊचाई समान हो िो उनिॳ िण िा अनदपाि लगभग कििना होगा?

1. 5:9 2. 5:18 3. 5:15 4. 5:6 11. A normal TV screen has a width to height

ratio of 4:3, while a high definition TV screen has a ratio of 16:9. What is the approximate ratio of their diagonals, if the heights of the two types of screens are the same?

1. 5:9 2. 5:18 3. 5:15 4. 5:6 12. स uा मि मान िी िदलनानदसार तनब न म सॳ

िन-सा ि न दसर सॳ भभ न हॴ?

1. एि वि िी पररतध व uास िा अनदपाि

2. रॳडडuन इिाई म एि समिल मभदज िॳ िीन िोण िा uोग

3. 22/7.

4. इिाई म uा िॳ गोलाधा व इिाई मuा इिाई ऊचाई िॳ ािद िॳ आuिन िा uोग

12. Comparing numerical values, which of the

following is different from the rest? 1. The ratio of the circumference of a

circle to its diameter. 2. The sum of the three angles of a

plane triangle expressed in radians. 3. 22/7. 4. The net volume of a hemisphere of

unit radius, and a cone of unit radius and unit height.

13. किसी नदी िी चााई 4.1 km हॴ। इस नदी पर बनॳ

पदल िी लबाई िा 1/7 भाग नदी िॳ एि िट पर ि ा 1/8 भाग नदी िॳ दसरॳ िट पर हॴ। पदल िी िद ल लबाई कििनी हॴ?

1. 5.1 km 2. 4.9 km 3. 5.6 km 4. 5.4 km

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13. A river is 4.1 km wide. A bridge built across it has 1/7 of its length on one bank and 1/8 of its length on the other bank. What is the total length of the bridge?

1. 5.1 km 2. 4.9 km 3. 5.6 km 4. 5.4 km 14. OA, OB, ि ा OC उस व ि िी म uाu हॴ

जजसिा एि च ाई भाग दाााuा गuा हॴ। AB िा मान भी व ि िी मuा िॳ मान िॳ समान हॴ।

िोण OCB िा मान स uा होगा? 1. 60 2. 75 3. 55 4. 65 14. OA, OB, and OC are radii of the quarter

circle shown in the figure. AB is also equal to the radius.

What is angle OCB? 1. 60 2. 75 3. 55 4. 65 15. 12 cm ि ा 1 cm िी म uा िॳ लोहॳ िॳ दो गोल

िा वपघला िर सuदस ि सuा गuा हॴ। लोहॳ िी षति बना, दो नuॳ गोलॳ बनाuॳ गuॳ ह। गोल िी सभा u म uाए ह

1. 9 and 4 cm 2. 9 and 10 cm 3. 8 and 5 cm 4. 2 and 11 cm 15. Two iron spheres of radii 12 cm and 1 cm are

melted and fused. Two new spheres are made without any loss of iron. Their possible radii could be

1. 9 and 4 cm 2. 9 and 10 cm 3. 8 and 5 cm 4. 2 and 11 cm

16. एि uजसि पuॳ 75/cL िी दर सॳ एल िोहोल खरीद िर व उसम पानी भमला िर पuॳ 75/cL

िी दर सॳ बॳच िर 50% लाभ िमािा हॴ। एल िोहोल व पानी िा अनदपाि कििना हॴ?

1. 2:1 2. 1:2 3. 3:2 4. 2:3 16. A man buys alcohol at Rs. 75/cL, adds water,

and sells it at Rs.75/cL making a profit of 50%. What is the ratio of alcohol to water?

1. 2:1 2. 1:2 3. 3:2 4. 2:3 17. एि वव-अिीu स uा िॳ अि िा uोग 9 हॴ।

उस भभन िा मान 3/4 हॴ जजसिा अा इस स uा सॳ 9 िम व हर 9 सॳ अतधि हॴ। स uा स uा हॴ?

1. 36 2. 63 3. 45 4. 54 17. The sum of digits of a two-digit number is 9.

If the fraction formed by taking 9 less than the number as numerator and 9 more than the number as denominator is 3/4, what is the number?

1. 36 2. 63 3. 45 4. 54 18. दो स ान X ि ा Y िॳ बीच िी दरी 1000 km हॴ।

एि uजसि X स ानीu समu 8 AM हवाई uामा वारा Y स ानीu समu 10 AM बजॳ सदबह पहदचिा हॴ। Y पर 4 घटॳ िॳ ववराम िॳ प चाि वह पदन: उसी ददन हवाई uामा वारा X िॳ स ानीu समu 4 PM बजॳ ााम लटिा हॴ। uजसि िी हवाई uामा िॳ दरान औसि गति कििनी हॴ?

1. 500 कि.मी. रति घटा 2. 250 कि.मी. रति घटा 3. 750 कि.मी. रति घटा 4. दी गई सचनानदसार ञाि नही किuा जा सििा।

18. The distance between X and Y is 1000 km. A

person flies from X at 8 AM local time and reaches Y at 10 AM local time. He flies back after a halt of 4 hours at Y and reaches X at 4 PM local time on the same day. What is his average speed for the duration he is in the air?

1. 500 km/hour 2. 250 km/hour 3. 750 km/hour 4. cannot be calculated with the given

information

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19. िोई uजसि अपनी सामा u गति सॳ x% िॳज चलिर सामा u समu सॳ y भमनट जल दी पहदचिा हॴ। uजसि िो सामाu गति सॳ चलनॳ पर कििना समu लगिा हॴ?

1. भमनट

2. भमनट

3. भमनट

4. भमनट

19. If a person travels x% faster than normal, he

reaches y minutes earlier than normal. What is his normal time of travel?

1. minutes

2. minutes

3. minutes

4. minutes

20. जस र गति सॳ चलनॳ वाली एि चलसोपान पर A

ि ा B एि िदम म एि सीढी ऊपर िी ओर चढिॳ ह। A िी गति B िी गति िो दोगदनी हॴ। सीढी िॳ ऊपरी िोर पर A 40 दम म ि ा B 30 दम म पहदचिॳ ह। uदद चलसोपान जस र हॴ िो उसिी कििनी सीदढuा (स टॳ स) ददखाई दगी?

1. 30 2. 40 3. 50 4. 60 20. A and B walk up an escalator one step at a

time, while the escalator itself moves up at a constant speed. A walks twice as fast as B. A reaches the top in 40 steps and B in 30 steps. How many steps of the escalator can be seen when it is not moving?

1. 30 2. 40 3. 50 4. 60

Hkkx \PART 'B'

21. तनब न दाााuॳ आिा सॳ उपuदस ििम pH िो चदन जजस पर अणद िॳ भलए ादि आवॳा ा u हो:

1. 2.02 2. 2.91 3. 5.98 4. 6.87 21. Choose the most appropriate pH at which the

net charge is zero for the molecule from the data shown below:

1. 2.02 2. 2.91 3. 5.98 4. 6.87 22. रामचरन लॉट म, पॳ टाईा िॳ बारॳ म किuॳ गuॳ

तनब न ि न म सॳ सही ि न चदन:

1. ढाचा रदहि पॳ टाईा िॳ सभी रीढ िी हीडी िॳ वविल िोण अननदमि षॳम म हगॳ।

2. इस तन िा पर पह दचना असभव हॴ कि स uा िोई पॳ टाईा पणाि: िद डभलनी uा पणाि: बीटा- प िर सपण अपनािा हॴ।

3. किसी पॳ टाईा म बीटा-मोा स पण िॳ पाuॳ जानॳ िा तनगमन किuा जा सििा हॴ।

4. पॳ टाईा िॳ अनदरम िा तनगमन किuा जा सििा हॴ।

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22. Choose the correct statement about peptides in the Ramachandran plot.

1. Peptides that are unstructured will have all the backbone dihedral angles in the disallowed regions.

2. It is not possible to conclude whether a peptide adopts entirely helix or entirely beta sheet conformation.

3. The occurrence of beta turn conformation in a peptide can be deduced.

4. The sequence of a peptide can be deduced. 23. किसी अभभकरuा िा साब uावस ा अचर

उ पाद एव अवस िर िी सारिाओ िा अनदपाि होिा हॴ। ि ा अभभकरuा िा मदस ि ऊजाा पररविान िॳ बीच िा सबध तनब नवि हॴ:

अभभकरuा A ि ा अभभकरuा B िॳ मान रमा: 10 ि ा 100 ह। िॳ सदभा म तनब न ि न म सॳ िन-सा सही हॴ?

1. 2. 3. 4.

23. Equilibrium constant of a reaction is a

ratio of product to substrate concentrations.

The relation between and free energy

change in a reaction is as follows

Reaction A and Reaction B have values

of 10 and 100, respectively. Which of the following statements is correct with respect to ?

1. 2. 3. 4.

24. ोरदार uाuाम िॳ बाद अतिररस ि ऑस सीजन िा

उपभोग इस िारण होिा हॴ:

1. मासपॳाी सॳ लॴजसटि अब ल िो पपन वारा तनिाल दॳनॳ।

2. मासपॳाी म लॴजसटि अब ल िी सारिा िो बढानॳ।

3. रस ि म ववलीन िॉबान डाuस साईा िो िम िरनॳ।

4. नव लिोजनन हॳिद ATP बनानॳ।

24. Excess oxygen consumed after a vigorous

exercise is

1. to pump out lactic acid from muscle. 2. to increase the concentration of lactic acid

in muscle. 3. to reduce dissolved carbon dioxide in

blood. 4. to make ATP for gluconeogenesis. 25. क फल पॳ िॳ रा भमि रिाuा िा वववरण तनब न म

सॳ िन-सा दॳिा हॴ?

1. ववपरि िॳ बाu पणाि म भलवपा-रोटीन अ uो uकरuा िो बढानॳ म सहाuिा िरना।

2. झिल ली िॳ एि पणाि सॳ दसरॳ िि िद ि फॉस फो भलवपा िो लॳ जाना। 3. वसा ववपरि म अतधि ऋणि: आवॳभाि झिल ली रो टीन िा स ानीिरण।

4. ल u झिल ली िॳ सा अदर आिी पददटिा िॳ सलuन िॳ बाद v-SNARES ि ा t-SNARES

िॳ अuद मन िो पॴदा िरना।

25. Which one of the following describes the

primary function of flippases? 1. Help in increasing lipid-protein interaction

in the outer leaflet of the bilayer 2. Move certain phospholipids from one

leaflet of the membrane to another 3. Localize more negatively charged

membrane proteins in the lipid bilayer 4. Cause uncoupling of v-SNARES and

t-SNARES after fusion of incoming vesicle with target membrane

26. M अवस ा म समसमणी साईजसलन-CDK

गतिववतध भाखर पर पहदचिी हॴ। uह इस िारण कि

1. माम M अवस ा म समसमणी साईजसलन िा स लॳण होिा हॴ।

2. माम प च G2 म समसमणी साईजसलन िा दॳहली स िर इिा होिा हॴ।

3. माम M अवस ा म फॉस फोररलीिरण वारा साईजसलन उपइिाई करuाजवि होिी हॴ।

4. माम M अवस ा म ववफॉस फोररलीिरण वारा िाईनॳ उपइिाई करuाजवि होिी हॴ।

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26. Mitotic cyclin-CDK activity peaks in M phase. This is because

1. Mitotic cyclin is synthesised only in M phase.

2. Threshold level of mitotic cyclin accumulates only in late G2.

3. Cyclin subunit is activated by phosphorylation only in M phase.

4. The kinase subunit is activated by dephosphorylation only in M phase.

27. डाuोभलuोतuल (DO), डाuपालभमटोतuल (DP),

डडस टॳरोतuल (DS) ि ा पालभमटोतuल ऑभलuोतuल (PO) वसा-अब ल सॳ बनॳ फॉस फादटडातuल िोलाईन (PC) म 'जॳल' सॳ रव स फदटिी अवस ा िि सरमण िाप, बढिॳ रम म हॴ:

1. DOPC > DPPC > POPC > DSPC 2. DSPC > DPPC > POPC > DOPC 3. DPPC > DSPC > DOPC > POPC 4. POPC > DPPC > DOPC > DSPC 27. The gel to liquid crystalline phase transition

temperature in phosphatidyl choline (PC) lipids composed of dioleoyl (DO), dipalmitoyl (DP), disteroyl (DS) and palmitoyl oleoyl (PO) fatty acids in increasing order will be

1. DOPC > DPPC > POPC > DSPC 2. DSPC > DPPC > POPC > DOPC 3. DPPC > DSPC > DOPC > POPC 4. POPC > DPPC > DOPC > DSPC 28. ववभभ न उपिोभािाई िो ठ िॳ बीच पारझिल ली

पररवहन िा एि उदाहरण तनब न म सॳ िन-सा नह हॴ?

1. िोभािार u सॳ अि:र uी जाभलिा िी अविाभािा िॳ अदर पररवहन

2. अि:र uी जाभलिा सॳ गोल गी सिद ल िि पररवहन

3. पीदठिा सॳ तचवपटााu स ान िि पररवहन

4. समिझणिीu आिझिाल ली स ान सॳ समिझणिीu आधामी िि पररवहन

28. Which of the following is NOT an example of

transmembrane transport between different subcellular compartments?

1. Transport from cytoplasm into the lumen of the endoplasmic reticulum

2. Transport from endoplasmic reticulum to the Golgi complex

3. Transport from stroma into thylakoid space 4. Transport from mitochondrial

intermembrane space into the mitochondrial matrix

29. RNA पॉभलमरॳ II सॳ तनब न म सॳ िन-सॳ अनदलॳझखि नह होिॳ?

1. miRNA ि ा िद ि snRNA

2. miRNA ि ा snoRNA

3. mRNA ि ा snoRNA

4. tRNA ि ा 5S rRNA

29. Which of the following are NOT transcribed

by RNA polymerase II? 1. miRNA and some snRNA 2. miRNA and snoRNA 3. mRNA and snoRNA 4. tRNA and 5S rRNA 30. RNA सपादन जो एि प चानदलॳखनीu रकरuा हॴ

मागादाी RNA (g-RNA) िी मदद सॳ सप न होिी हॴ। इस रकरuा िॳ बारॳ म किuॳ गuॳ तनब न ि न म सॳ िन-सा सही नह हॴ?

1. गतिलवि DNA म g-RNA तनभार RNA

सपादन घदटि होिा हॴ।

2. t-RNA िॳ रासाuतनि पररविान म g-RNA सजबमभलि हॴ।

3. uररडडन िा तनवॳा uा लोपन इस रकरuा म सजबमभलि हॴ।

4. जो अनदरम एि बार सपाददि हदuॳ, उनिो एि दसरॳ g-RNA िॳ उपuोग सॳ पदन: सपाददि किuा जा सििा हॴ।

30. RNA editing, a post-transcriptional process, is

achieved with the help of guide RNA (g-RNA). Which one of the following statements about the process is NOT true?

1. g-RNA dependent RNA editing happens in the kinetoplast DNA

2. g-RNA is involved in chemical modification of t-RNA

3. This process involves insertion or deletion of uridines

4. Sequences edited once may be re-edited using a second g-RNA

31. टॳलोमरॳ, एि RNA-रोटीन सिद ल, जो DNA

स लॳण िॳ दरान अ uाा िॳ रतिितिuन िो सपणा िरिा हॴ, हॴ एि ववभा ट

1. RNA तनभार DNA पॉभलमरॳ

2. DNA तनभार DNA पॉभलमरॳ

3. DNA तनभार RNA पॉभलमरॳ

4. RNA तनभार RNA पॉभलमरॳ

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31. Telomerase, a RNA-protein complex which completes the replication of telomeres during DNA synthesis, is a specialised

1. RNA dependent DNA polymerase 2. DNA dependent DNA polymerase 3. DNA dependent RNA polymerase 4. RNA dependent RNA polymerase 32. 10.5 bp रति फॳ रा िॳ सा 10 पणा फॳ र िॳ एि लघद

ववर जदि DNA अणद पर ववचार। DNA अणद िॳ िोर एि सा बॴठाuॳ जािॳ ह, िाकि एि ढीला व ि बन जाu। इस ढीलॳ व ि िी uोजि स uा होगी

1. 105 2. 20.5 3. 10.0 4. 10.5 32. Consider a short double-stranded linear DNA

molecule of 10 complete turns with 10.5 bp/turn. The ends of the DNA molecule are sealed together to make a relaxed circle. This relaxed circle will have a linking number of

1. 105 2. 20.5 3. 10.0 4. 10.5

33.

उपरोस ि सिॳ िन सोपन म तनब न अणदओ म सॳ िन-सा, ‘B’सॳ तनददा ट किuा गuा हॴ?

1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4

33.

In the above signalling cascade, which one of

the following molecules is denoted by ‘B’? 1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4 34. वॳस टना ाोण रuोग म रा भमि रतिरषषu िॳ

ससचन म नॴ u उपuोग म आनॳ वाली वविीuि रतिरषी ह

1. रतिअपररपी 2. रतिववभा टरपी

3. ववमरपी 4. रतिपरारपी

34. The secondary antibodies routinely used for

the detection of primary antibodies in western blotting experiment are

1. anti-allotypic 2. anti-idiotypic 3. anti-isotypic 4. anti-paratypic 35. एि सामा u िोभािा िा िॴ सर िभािा म

पािरण तनब न घटनाओ म सॳ किससॳ सामा uि: नह होगा?

1. अबदादजीन िॳ रिाuा िी लजध

2. अबदाद सदमि िॳ रिाuा िी षति

3. uजसलuोटाईा उछ िॳदीषतिसदधार म सजबमभलि जीन िॳ रिाuा िी लजध

4. रािएपो टोभसस सबतधि जीन िॳ रिाuा िी षति

35. Which of the following events will NOT

usually lead to transformation of a normal cell into a cancer cell?

1. Gain of function of oncogenes 2. Loss of function of tumor suppressors 3. Gain of function of genes involved in

nucleotide excision repair 4. Loss of function of pro-apoptosis related

genes

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36. तनब न म सॳ िन-सा एि आहर-वदहि जीव वव हॴ?

1. टॴटानस जीव वव

2. बोटदलीनम जीव वव

3. हॴजा जीव वव

4. रोदहणी जीव वव

36. Which one of the following is a food borne

toxin? 1. Tetanus toxin 2. Botulinum toxin 3. Cholera toxin 4. Diptheria toxin 37. तनब न ि न म सॳ िन-सा गलत हॴ?

1. बीजाड िॳ गदबीजाणदवादहिा िॳ अदर गदबीजाणदजनि िा वविास होिा हॴ।

2. चार अगदझणि दीघागोलि िॳ उ पादन हॳिद गदबीजाणदजनि अधासमण अनदभव िरिा हॴ।

3. अतधिाा आविबीजजu म मादा uद मिोतदद बनानॳ िॳ भलए सभी चार गदबीजाणद िई समसमणी ववभाजन अनदभव िरिॳ ह।

4. मादा uद मिोतद अगदझणि हॴ।

37. Which one of the following statements is

WRONG? 1. The megasporocyte develops within the

megasporangium of the ovule 2. Megasporocyte undergoes meiosis to

produce four haploid megaspores 3. All the four megaspores undergo several

mitotic divisions to form female gametophyte in most angiosperms

4. Female gametophyte is haploid

38. िद ि रोटीन uा mRNAs जो अतनॳतचि अाॳ िॳ अदर षॳमीuि: स ानीिररि ह ि ा वविास िा तनuमण िरिॳ ह, िहलािॳ ह:

1. जीन तनuामि

2. आिरभम िीu तनधाारि

3. िोभािा र uी तनधाारि

4. मो ॳि बनािॳ िारि

38. Certain proteins or mRNAs that are regionally

localized within the unfertilized egg and regulate development are called

1. gene regulators. 2. morphometric determinants.

3. cytoplasmic determinants. 4. mosaic forming factors.

39. किसी भी जीव िॳ वविास िॳ भलए िोभािा सॳ

िोभािा िि सचार मह वपणा हॴ। एि ववभा ट रॳरि सिॳ ि पर िोभािाओ िॳ अनदकरuा िरनॳ िा सामथ uा िहलािा हॴ

1. रॳरणा िी षॳमीu ववभा टिा

2. uो uिा

3. रावास न सिॳ िन

4. भाषारद अ uो uकरuा

39. Cell to cell communication is important in

development of an organism. The ability of cells to respond to a specific inductive signal is called

1. Regional specificity of induction 2. Competence 3. Juxtracrine signalling 4. Instructive interaction 40. चिद पादी पाद वविास हॳिद ाीास बदह: वचीu

िटि रॳरण आव uि हॴ। एि करuााील पाद िी सरचना िॳ भलuॳ तनम न म सॳ िन-सा आव uि नह हॴ?

1. Tbx जीन एव Wnt

2. एरोस टॴरोन

3. एपो टोदटि जीन

4. फाई रो लास ट वविास िारि

40. Apical ectodermal ridge induction is essential

for tetrapod limb development. Which one of the following is NOT essential for the formation of a functional limb?

1. Tbx genes and Wnt 2. Androsterone 3. Apoptotic genes 4. Fibroblast growth factor 41. किसी पादप मल िॳ बाu वचा सॳ अिस वचा िि

जल रवाह िॳ ससदघदटि प िा तनब न म सॳ िन-सा रॳ ठिम वणान िरिा हॴ?

1. जल किसी झिल ली िो पार किuॳ बना िोभािा भभजिu ि ा बाuिोभािा स ान म गतिाील होिा हॴ।

2. जल मल वल िद ट िॳ आर-पार जीवर uििद सॳ होिर uामा िरिा हॴ।

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3. जल अपनॳ प म हर िोभािा िी लमा झिल ली िो दो बार पार िरिा हॴ, एि बार अदर आिॳ हदuॳ ि ा एि बार बाहर जािॳ हदए।

4. टोनो लस ट िॳ आर-पार पररवहन।

41. Which one of the following best describes the

symplast pathway of water flow from the epidermis to endodermis in a plant root?

1. Water moves through cell walls and extracellular spaces without crossing any membrane

2. Water travels across the root cortex via the plasmodesmata

3. Water crosses the plasma membrane of each cell in its path twice, once on entering and once on exiting

4. Transport across the tonoplast 42. ाािनााी डाईस लोरोफीनाईलडाईमी ॴलuररuा हॴ

इसिा सदमि:

1. ऐरोमॴदटि एभमनो अब ल िॳ जॴवस लॳण िॳ भलए भाकिमॳट प

2. P680 सॳ P700 िि इलॴस रॉन पररवहन

3. ााझखि ाखला एभमनो अब ल प

4. P700 सॳ फॳ रोडॉस सीन िि इलॴस रॉन पररवहन

42. The herbicide, dichlorophenyldimethylurea, is

an inhibitor of 1. shikimate pathway for biosynthesis of

aromatic amino acids. 2. electron transport from P680 to P700. 3. branched chain amino acid pathway. 4. electron transport from P700 to ferredoxin. 43. तनब न uतगि म सॳ िन-सा, वविीuि

उपापचuज िॳ ऐल िॳ लाईा वगा िा एि भाग नह हॴ?

1. भलजनन 2. इ डोल

3. रोपॳन 4. वपरोभल डीन 43. Which one of the following compounds is

NOT a part of alkaloid class of secondary metabolites?

1. Lignin 2. Indole 3. Tropane 4. Pyrrolidine 44. तनब न पादपो प न सिॳ िन अणदओ म सॳ िन-सा

िचािीu िविमली िवि िॳ िविििद ाासन िो रॳररि िरिा हॴ, जो इन िवि िॳ उपतनवॳान िॳ रारभभि चरण म रॳषषि एि घटना हॴ?

1. सॴभलभसभलि अब ल 2. एजसभसि अब ल

3. जसरगोलॴस टोनस 4. भसस टॳभमन

44. Which one of the following plant derived

signalling molecules induces hyphal branching of arbuscular mycorrhizal fungi, a pheno-menon that is observed at the initial stages of colonization by these fungi?

1. Salicylic acid 2. Abscisic acid 3. Strigolactones 4. Systemin 45. सीरम िी बनाबट आव uिि: लाामा िी बनावट

जॴसॳ ही हॴ, अलावा इसक कि उसम uह नही हॴ:

1. एल बदभमन

2. स टवटा-रवर िारि

3. रतिहीमोक फभलि िारि

4. हॴजमन िारि

45. Serum has essentially the same composition as

plasma EXCEPT that it lacks 1. Albumin 2. Stuart-Prower factor 3. Antihemophilic factor 4. Hageman factor 46. दाबरादहu िॳ उदीपन िॳ िारण तनब न म सॳ िन-

सा नह पॴदा होिा?

1. रॴडडिाडड ाuा

2. अवरस िचाप

3. भारा ववस फारण

4. वादहिासिीणान

46. Which one of the following does NOT occur

due to stimulation of baroreceptors? 1. Bradycardia 2. Hypotension 3. Venodilation 4. Vasoconstriction 47. वॴसोरॳजससन राव इसिॳ सा नह बढिा:

1. uाuाम

2. बदहिोभािाई रव आuिन म ववि

3. खाा होना

4. उल टी िरना

47. Vasopressin secretion does NOT increase with 1. exercise 2. an increase in extracellular fluid volume 3. standing 4. vomiting

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48. जठररत म जस ि िोभािाओ िा िन-सा रिार, दहस टाभमन िॳ मदस िन िॳ भलए उ िरदाuी हॴ?

1. लॳ म िठ िोभािाu

2. ए टरोरोमाफीन-जॴसी िोभािाu

3. मद u िोभािाu

4. भभजिल न िोभािाu

48. Which type of cells located in gastric glands is

responsible for the release of histamine? 1. Mucous neck cells 2. Enterochromaffin-like cells 3. Chief cells 4. Parietal cells 49. uदद अधासमण I म अववuोजन घटिा हॴ, तनब न

परर u म अतिसभा uि: िन-सा घटॳगा?

1. दो uद मि n+1 हगॳ ि ा दो n-1 हग।

2. एि uद मि n+1 हगा, ि ा दो ‘n’ ि ा एि n-1 होगा।

3. दो uद मि सामा u हगॳ ि ा दो n-1 हगॳ।

4. दो uद मि सामा u हगॳ ि ा दो n+1 हगॳ। 49. If non-disjunction occurs in meiosis I, which

of the following scenario is most likely to occur?

1. Two gametes will be n+1 and two will be n-1

2. One gamete will be n+1, two will be ‘n’ and one will be n-1

3. Two gametes will be normal and two will be n-1

4. Two gametes will be normal and two will be n+1

50. किसी जीन उ पाद म एिल एभमनो अब ल िॳ

पररविान म पररणभमि िरनॳ वाला तनब न उ पररविाजन म सॳ िन-सा अतिसभा uि: हॴ?

1. एकरडीन ऑरज

2. X-ववकिरण

3. ई ॴलमी ॳन सल फोनॳट (EMS)

4. एत डडuम रोमाईट

50. Which of the following mutagens is most

likely to result in a single amino acid change in a gene product?

1. Acridine orange 2. X-rays 3. Ethylmethane sulphonate (EMS) 4. Ethidium bromide

51. घघॳ (Limnaea peregra) िॳ ाख िॳ िद डलीभवन िी ववरासि मािवाी हॴ, uह सदरतिजठि हॴ। दषषणाविा िद डलन रभावी एलील D पर तनभार हॴ ि ा वामाविा िद डलन अरभावी एलील d पर तनभार हॴ।

दषषणाविा (Dd) रिार िी सिान मादा F1 िो नर वामाविा घोघ सॳ रसिररि किuा जािा हॴ। उसिॳ F2 सिान म ववमuद मी: समuद मी uजटu िा अनदपाि स uा होगा?

1. 3:1 2. 1:1 3. 1:3 4. 1:2:1

51. Maternal inheritance of coiling of shell in snail (Limnaea peregra) is well established. The dextral coiling depends on dominant allele D and sinistral coiling depends upon recessive allele d. A female F1 progeny of dextral (Dd) type is crossed with a male sinistral snail. What will be the ratio of heterozygous: homozygous individuals in its F2 progeny?

1. 3:1 2. 1:1 3. 1:3 4. 1:2:1

52. तनब न म सॳ िन-सा F लाज मड रखनॳवाली िोभािाओ िॳ भलए सही हॴ?

1. उनिा F लाज मड अिाuााील हॴ।

2. वॳ सभी गदणसमी जीन िी बविि स ानािरण गतिuा दााािी ह।

3. वॳ अाववगदझणि ह।

4. वॳ जीववि रहनॳ म ववफल होिॳ ह स uकि रतिितिuन िी गदणसमी उ पजि तनजरतuि हॴ।

52. Which of the following is true for cells

harbouring F plasmid? 1. Their F plasmid is non-functional. 2. They exhibit increased rates of transfer of

all chromosomal genes. 3. They are merodiploids. 4. They fail to survive as the chromosomal

origin of replication is inactivated. 53. एि स लोरोक फल a uदस ि ाॴवाल, जजसिा सचuी

उ पाद सदपद पी स टाचा हॴ ि ा जजसम िााभी िोभािाओ िा अभाव हॴ, इस वगा िा सदस u हॴ

1. बरदाॴवाल वगा

2. स लोरोफाइसी वगा

3. लालाॴवाल वगा

4. पीिहररि ाॴवाल वगा

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53. An alga having chlorophyll a, floridean starch as storage product and lacking flagellate cells belongs to the class

1. Phaeophyceae. 2. Chlorophyceae. 3. Rhodophyceae. 4. Xanthophyceae. 54. तनब न म सॳ िन-सा एिबीजपमu िॳ भलए सही

नह हॴ?

1. सहचर िोभािाओ िॳ सा चालनी नभलिा सदस u

2. सवहन- uास वविीणारभी

3. मववदरिी पराग

4. सवहनी एधा िा अभाव

54. Which of the following is NOT true for

monocots? 1. Sieve tube members with companion cells 2. Vasculature atactostelic 3. Tricolpate pollen 4. Vascular cambium absent 55. किसी ववभा ट राितिि तनवास म रहिॳ uजट,

ि ा उसिॳ सा जो समलषणानदिभलि परिद समजीनीuि: अनदिभलि नही हॴ, िहलािॳ ह:

1. अनदिलि 2. पारररिार

3. पाररजाति 4. सरजाति 55. Individuals occupying a particular habitat and

adapted to it phenotypically but not genotypically are known as

1. Ecophenes. 2. Ecotypes. 3. Ecospecies. 4. Coenospecies. 56. तनब न ि न म सॳ िन-सा, जीवन इतिहास

ववाॳिाओ िॳ रमवविास म लॳन-दॳन िी सिल पना िो सम ान िरिा हॴ?

1. जनिीu दॳखभाल िा स िर ि ा सराह आिार िा धन सहसबध हॴ।

2. ाीर वuस ि होिॳ राणी दीघाजीवी रवजि िॳ होिॳ ह।

3. बीज आिार म ववि सामा uि: बीज स uा म षति िॳ सा सगि हॴ।

4. रजनन हॳिद अतधि ऊजाा िा आबटन अतधि जनस uा ववि म पररणभमि होिा हॴ।

56. Which one of the following statements supports the concept of trade-off in the evolution of life history traits?

1. Level of parental care and clutch size are positively correlated

2. Animals maturing early tend to live longer 3. An increase in seed size is usually

associated with a decrease in seed number 4. Allocation of higher energy for reproduce-

tion leads to higher population growth 57. जनस uा घन व िॳ फलन िॳ प म dN/dt िा

रॳखातचम रदान िरिा हॴ एि

1. समिोणीu अतिपरवलu

2. ऋण चरघािािी वर

3. धन सरलरॳखी वर

4. घटी आिार िा वर

57. A plot of dN/dt as a function of population

density yields a 1. rectangular hyperbola. 2. negative exponential curve. 3. positive rectilinear curve. 4. bell-shaped curve.

58. वविपाि वविास िरिॳ एि रजाति िॳ भलए, uदद

K = 20,000 ि ा r = 0.15 ह, िो उछ चिम रतिपालनीu राजि होगी:

1. 450 2. 1500 3. 3000 4. 6000 58. For a species having logistic growth, if K =

20,000 and r = 0.15, the maximum sustainable yield will be

1. 450 2. 1500 3. 3000 4. 6000 59. पादप िॳ मल: ररोह अनदपाि िॳ आधार पर तनब न

म सॳ िन-सी पाररिम िी सही रॳणी हॴ?

1. उ णिदटबि आरा वन> उ णिदटबि ाद ि वन>

ाीिो ण घास भभम> उ णिदटबि घास भभम

2. ाीिो ण घास भभम > उ णिदटबि घास भभम >

उ णिदटबि आरा वन > उ णिदटबि ाद ि वन

3. उ णिदटबि ाद ि वन > उ णिदटबि आरा वन >

उ णिदटबि घास भभम > ाीिो ण घास भभम


उ णिदटबि ाद ि वन > उ णिदटबि आरा वन

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59. Which of the following is a correct ranking of ecosystems based on the root: shoot ratio of plants?

1. Tropical wet forest > Tropical dry forest > Temperate grassland > Tropical grassland

2. Temperate grassland > Tropical grassland > Tropical wet forest > Tropical dry forest

3. Tropical dry forest > Tropical wet forest > Tropical grassland > Temperate grassland

4. Temperate grassland > Tropical grassland > Tropical dry forest > Tropical wet forest

60. तनब न िल प म सॳ िन-सा “म सu िा uदग”

माना जािा हॴ?

1. डॳवोतनuन 2. जराभसि

3. िरuन 4. िॉबोतनफॳ रस

60. Which of the following periods is known as

“Age of Fishes”? 1. Devonian 2. Jurassic 3. Cambrian 4. Carboniferous 61. हाडी-वाईनबगा रतिमान िी धारणा तनब न म सॳ

स uा नह हॴ?

1. र नाधीन ववस ल िॳ सदभा म जनस uा uाजछिि सगम िरिी हॴ।

2. रनाधीन ववस ल पर वरण िाम नही िरिा।

3. इस ववस ल पर एि एलील रभावी ि ा दसरा अरभावी हॴ।

4. जनस uा रभावि: आिार म अनि हॴ।

61. Which of the following is NOT an assumption

of the Hardy-Weinberg model? 1. Population mates at random with respect to

the locus in question 2. Selection is not acting on the locus in

question 3. One allele is dominant and the other is

recessive at this locus 4. The population is effectively infinite in size 62. तनब न भवॴञातनि िल प म िन-सा स ितनu िॳ

पहलॳ आववभााव सॳ लषझणि हॴ?

1. ििीuि 2. रॴ टॳभाuस

3. पभमामन 4. राuाभसि

62. Which of the following geological periods is

characterized by the first appearance of mammals?

1. Tertiary 2. Cretaceous 3. Permian 4. Triassic

63. भलग िॳ बीच रजननीu सफलिा पर अभभतच िा परस पर ववरोध तनब न सगम िम म किसम राu: नह होगा?

1. बहदपति व 2. एिप नी व

3. स वछ ि द 4. बहदप नी व

63. In which of the following mating systems

there is likely to be NO conflict of interest over reproductive success between the sexes?

1. Polyandry 2. Monogamy 3. Promiscuity 4. Polygamy 64. तनब न वव लॳिी ििनीि म किसम रिााीu

मापन सजबमभलि नह हॴ? 1. ELISA

2. माइरोऐरॳ

3. रवाह साईटोमॳरी

4. ववभॳदी रमवीषण ऊ मामापी

64. Which one of the following analytical techni-ques does NOT involve an optical measurement?

1. ELISA 2. Microarray 3. Flow cytometry 4. Differential Scanning Calorimetry

65. िपास गोलि िभम, िबाि िलिा िभम ि ा गदलाबी गोलि िभम िॳ ववि रतिरोध पानॳ िॳ भलए बोलगाडा II िपास म िन-सॳ जीन सजनवव ट किuॳ गuॳ हॴ?

1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab 65. Which genes have been introduced in Bollgard II

cotton to get resistance against cotton bollworm, tobacco budworm and pink bollworm?

1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab 66. मानव िॳ ECG िो अकिि िरनॳ ववभभ न िार

उपuोग म आिॳ ह। तनब न म सॳ िन-सा एिरदवी िार नह हॴ?

1. वविि पाद िार

2. V1 ि ा V2 िार

3. मानि पाद िार

4. VR ि ा VL िार

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66. Different leads are used to record ECG of humans. Which one of the following is NOT unipolar leads?

1. Augmented limb leads 2. V1 and V2 leads 3. Standard limb leads 4. VR and VL leads 67. िोभािाओ म ववाॳ mRNAs िी उपजस ति एव

बटन इससॳ ससतचि किuा जा सििा हॴ:

1. ना ान ाोण वव लॳण

2. RNase रषा आमापन

3. स ानॳ सिरण

4. वा स िववि समu PCR

67. The presence and distribution of specific

mRNAs within a cell can be detected by 1. Northern blot analysis 2. RNase protection assay 3. in situ hybridization 4. real-time PCR 68. गहरॳ घाव िॳ भलए मानव िो दी जानॳ वाली टॴटानस

टीिा हॴ एि

1. DNA टीिा

2. पदनuोगज सवाहि टीिा

3. उपइिाई टीिा

4. टास साईा टीिा

68. The tetanus vaccine given to humans in the

case of a deep cut is a 1. DNA vaccine 2. recombinant vector vaccine 3. subunit vaccine 4. toxoid vaccine 69. दो पॳ टाईड िॳ एि भमरण िी ववuदि

आuनीिरण वणामाला m/z मान 301, 401, 501,

ि ा 601 म ाीा दााािा हॴ। पॳ टाइड िॳ अणदभार ह

1. 1200 ि ा 1250

2. 1200 ि ा 1500

3. 1350 ि ा 1500

4. 1250 ि ा 1350

69. The electrospray ionization spectrum of a mixture of two peptides show peaks with m/z values 301, 401, 501, and 601. The molecular weights of the peptides are

1. 1200 and 1250 2. 1200 and 1500 3. 1350 and 1500 4. 1250 and 1350 70. एि रादटuॳ िॳ सा पाचन सॳ पवा ि ा प चाि

एि रोटीन िॳ रिााीu मापन भलuॳ जािॳ ह। तनब न वणामाला मापन म किसम सिॳ ि िा पररविान, अ ााि रोदटuॳ उपचार सॳ पवा ि ा प चाि, उछ चिम हो सििा हॴ?

1. 280 नॴ.मी. पर अवाोणाि

2. व िीu वववणािा


4. रतिदीजि मान

70. An optical measurement of a protein is taken

both before and after digestion of the protein by a protease. In which of the following spectroscopic measurements the signal change, i.e., before vs after protease treatment, could be the maximum?

1. Absorbance at 280 nm 2. Circular dichroism 3. Absorbance at 340 nm 4. Fluorescence value

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Hkkx \PART 'C'

71. तनब न ि न म सॳ,

A. हाईरोजन, ीuदटीररuम ि ा दरभाuम अपनी रोटॉन स uाओ म भभ न ह।

B. हाईरोजन, ीuदटीररuम ि ा दरभाuम अपनी uरॉन स uाओ म भभ न ह।

C. ीuदटीररuम ि ा दरभाuम दोन रोडडuोधमी ह, ि ा रमा: हाईरोजन ि ा ीuटीररuम म षतuि होिॳ ह।

D. दरभाuम रॳडडuोधमी हॴ ि ा हीभलuम म षतuि होिा हॴ।

E. िॉबान-14 नाईरोजन-14 म षतuि होिा हॴ।

F. िॉबान -14 िॉबान -13 म षतuि होिा हॴ।

सभी सही ि न िा सuोजन चदन:

1. A, B ि ा F 2. B, D ि ा E

3. A, C ि ा D 4. C, E ि ा F 71. From the following statements, A. Hydrogen, Deuterium and Tritium differ in

the number of protons B. Hydrogen, Deuterium and Tritium differ in

the number of neutrons C. Both Deuterium and Tritium are

radioactive and decay to Hydrogen and Deuterium, respectively D. Tritium is radioactive and decays to

Helium E. Carbon-14 decays to Nitrogen-14 F. Carbon-14 decays to Carbon-13 pick the combination with ALL correct

statements. 1. A, B and F 2. B, D and E 3. A, C and D 4. C, E and F 72. तनब न ि न म सॳ,

A. किसी अभभकरuा िो स वि: घटनॳ िॳ भलए मदस ि ऊजाा पररविान ऋण होना चादहए

B. गॴस अवस ा म दो नाईरोजन अणदओ िॳ बीच िी अ uो uकरuा रमदखि: ववuदि- स ॴतिि हॴ।

C. आबध ऊजााओ िी जानिारी सॳ uह तनणाu लॳना सभव हॴ कि स uा िोई आबध सहसuोजि आबध हॴ uा हाईरोजन आबध

D. एि वभलि लो uदलर रोटीन म जलववरागी अ uो uकरuाu मह वपणा नही हॴ।

सभी गलत ि न िा सuोजन चदन: 1. A ि ा B 2. B ि ा C

3. C ि ा D 4. B ि ा D

72. From the following statements, A. For a reaction to occur spontaneously

the free energy change must be negative B. The interaction between two nitrogen

molecules in the gaseous state is predominantly electrostatic

C. By knowing bond energies, it is possible to deduce whether the bond is covalent bond or hydrogen bond

D. Hydrophobic interactions are not important in a folded globular protein

pick the combination with ALL WRONG statements.

1. A and B 2. B and C 3. C and D 4. B and D 73. पॳ टाईड-रोटीन सपण िॳ बारॳ म तनब न चार ि न ह:

A. ि ा िॳ रामचरन लॉट म लाईसीन िॳ सपणि: अनदमि स ान िा उछ चिम षॳमफल हॴ।

B. N-भसरॳ पर एभसदटलीिि ि ा C-भसरॳ पर अमाइडीिि एि A 20-अवाॳ पॳ टाईा िा

सभी अवाॳ िॳ भलए हॴ। uह तन िा पर पहदचा जा सििा हॴ कि पॳ टाईड िा सपण िद डभलनी-िद डभलि-र जदि हॴ।

C. लघद पॳ टाईड िॳ भलए किसी रोटीन िॳ एभमन अब ल िॳ िॳ अनदमि मान वॴध नही ह।

D. एि पॳ टाईा एसॳदटल-A1-A2-A3-A4-CONH2 (A1-A4

एभमनो अब ल ह) एि सदपररभावि -िद डली अपनािा हॴ। A2 ि ा A3 िॳ वविल िोण -िद डली िॳ रिार िो तनधााररि िरिॳ ह।

सही ि न िॳ सuोजन िो चदन:

1. A ि ा B 2. B ि ा C

3. A ि ा D 4. C ि ा D

73. The following are four statements on peptide/

protein conformation: A. Glycine has the largest area of conforma-

tionally allowed space in the Ramachandran plot of

B. A 20-residue peptide that is acetylated at the N-terminus and amidated at the C- terminus

has for all the residues. It can be concluded that conformation of the peptide is helix-turn-strand

C. The allowed values of for amino acids in a protein are not valid for short peptides

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D. A peptide Acetyl-A1-A2-A3-A4-CONH2 (A1- A4 are amino acids) adopts a well defined - turn. The dihedral angles of A2 and A3 determine the type of -turn

Choose the combination of correct statements. 1. A and B 2. B and C 3. A and D 4. C and D 74. समववuदि बदद 6.5 िॳ एि रोटीन, जो िॴ जलाuम सॳ

बधिा हॴ, पर जस तिu िॳ एि समदछ चu पर एि ाोधििाा नॳ अनदसधान किuा। इस रोटीन पर चार स विम उपचार लाग किuॳ गuॳ। (i) pH 6.4, (ii) 10%

जलसॳरॉल, (iii) 10 mM CaCl2, (iv) 40% अब मोतनuम सल फॳ ट। इसिॳ बाद अपिरीिरण एव अतध लवी म रोटीन िा आिलन किuा गuा। तनब न आलॳख म पररणाम दाााuॳ गuॳ ह:

आलॳख म दाााuॳ पररणाम िा तनब न उपचार म सॳ िन-सा रॳ ठिम रतितनतध व िरिा हॴ?

1. a = अब मोतनuम सल फॳ ट, b = जलसॳरॉल, c = pH 6.4, d = CaCl2

2. a = CaCl2, b = जलसॳरॉल, c = अब मोतनuम सल फॳ ट, d = pH 6.4

3. a = pH 6.4, b = CaCl2, c = अब मोतनuम सल फॳ ट, d = जलसॳरॉल

4. a = CaCl2, b = pH 6.4, c = जलसॳरॉल,

d = अब मोतनuम सल फॳ ट 74. A researcher investigated a set of conditions for

a protein with an isoelectric point of 6.5 and also binds to calcium. This protein was subjected to four independent treatments: (i) pH 6.4, (ii) 10% glycerol, (iii) 10 mM CaCl2, (iv) 40% ammonium sulphate. This was followed by centrifugation and estimation of the protein in the supernatant. The results are depicted in the graph below:

Which of the following treatments best

represents the results shown in the graph? 1. a = ammonium sulphate, b = glycerol, c = pH 6.4, d = CaCl2 2. a = CaCl2, b = glycerol, c = ammonium

sulphate, d = pH 6.4

3. a = pH 6.4, b = CaCl2, c = ammonium sulphate, d = glycerol

4. a = CaCl2, b = pH 6.4, c = glycerol, d = ammonium sulphate

75. uरीन िॳ जॴवस लॳण म :

1. सभी N परमाणद, C4 ि ा C5 एस पादटाि अब ल सॳ ह।

2. Nl एस पादटाि अब ल सॳ हॴ; N3 ि ा N9 लटाभमन पा वा ाखला सॳ ह; N7, C4 ि ा C5 लाईसीन सॳ ह।

3. Nl एस पादटाि अब ल सॳ हॴ; N3 लटाभमन पा वा ाखला सॳ हॴ; N9 लटाभमन िॳ C सॳ सलजनि N

सॳ हॴ; N7, C4 ि ा C5 लाई सीन सॳ ह।

4. Nl लटाभमन सॳ हॴ; N3 लटाभमन पा वा ाखला सॳ हॴ; N9 लटाभमन िॳ C सॳ सलजनि N सॳ हॴ; N7,

C4 ि ा C5 लाई सीन सॳ ह।

75. In the biosynthesis of purine:

1. All N atoms, C4 and C5 are from aspartic acid

2. Nl is from Aspartic acid; N3 and N9 are from Glutamine side-chain; N7, C4 and

C5 are from Glycine

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3. Nl is from Aspartic acid; N3 from Glutamine side-chain; N9 from N attached to C of Glutamine; N7, C4 and C5 are from Glycine

4. Nl is from Glutamine; N3 from Glutamine side-chain; N9 from N attached to C of Glutamine; N7, C4 and C5 are from Glycine

76. एि ही करuाधार पर दो अलग ए ाईम, X ि ा Y,

िी करuाधार ववभा टिा पर एि ाोधििाा अनदसधान िरिा ा। दोन ए जाइम पर ऊ मा uा ए ाइम गतिववतध िो सदभमि िरनॳ वालॳ सदमि िॳ सा उपचार किuा गuा। पाuॳ गuॳ पररणाम तनब नवि ह, जहा a=सदमि उपचार, b=ऊ मा उपचार, ि ा c=तनuमण

तनब न ि न म सॳ िन-सा सही हॴ?

1. किuाधार S िॳ भलए माम रोटीन X ववभाट हॴ।

2. किuाधार S िॳ भलए माम रोटीन Y ववभाट हॴ।

3. किuाधार S िॳ भलए X ि ा Y, दोन ववभाट हॴ।

4. किuाधार S िॳ भलए X ि ा Y, दोन अववभाट हॴ।

76. A researcher was investigating the substrate

specificity of two different enzymes, X and Y, on the same substrate. Both the enzymes were subjected to treatment with either heat or an inhibitor which inhibits the enzyme activity. Following are the results obtained where a=inhibitor treatment, b=heat treatment and c=control.

Which of the following statements is correct? 1. Only protein X is specific for the substrate, S 2. Only protein Y is specific for the substrate, S 3. Both X and Y are specific for the substrate, S 4. Both X and Y are non-specific for the substrate, S 77. किसी रuोग म लाल रस ि िोभािाu अप घदटि िी

गuी ि ा जो िोभािाu टटी नही वॳ 600g म अपिरीिरण वारा तनिाल ददए गए। अतध लवी िो लॳिर 100,000g पर अपिरीिरण किuा गuा। 5M

NaCl िॳ सा गददटिा तनिाली गuी ि ा कफर 100,000g पर अपिरीिरण किuा गuा। अतध लवी म तनबन रोटीन म सॳ िन-सा उपजस ि होगा?

1. बड 3 2. लाईिोफोरीन

3. G रोटीन uदजमि राही 4. स पॴजसरन 77. In an experiment, red blood cells were

subjected to lysis and any unbroken cells were removed by centrifugation at 600g. The supernatant was taken and centrifuged at 100,000g. The pellet was extracted with 5M NaCl and again centrifuged at 100,000g. Which of the following proteins would be present in the supernatant?

1. Band 3 2. Glycophorin 3. G protein-coupled receptor 4. Spectrin 78. रोटीन ‘A’ िॳ अििोभािीu uािाuाि िॳ अ uuन

हॳिद, उसॳ GFP (A-GFP) सॳ लॳबभलि किuा गuा। रतिदीजि स मदाान नॳ दाााuा कि A-GFP, LAMP1 िॳ सा सहस ानीिि होिा हॴ। बॴक फलोमाईसीन A, जो H+-ATPase िा एि सदमि हॴ, िी उपजस ति म A-GFP, LAMP1 िॳ सा सहस ानीिि नही होिा। इसिॳ बजाu, वह LC3

पद स टा िॳ सा सहस ानीिररि होिा हॴ।

तनब न ि न म सॳ िन-सा सह हॴ?

1. बॴक फलोमाईसीन A िी अनदपजस ति म A-GFP, ER पर लजuि होिा हॴ।

2. A-GFP िॳ लuनिाu िि uािाuाि िॳ भलए स वभोजजिा िी आव uििा हॴ।

3. बॴक फलोमाईसीन A, ER पर A-GFP िो लजuि िरानॳ म अनदिलन दॳिा हॴ।

4. बॴक फलोमाईसीन A, A-GFP िो सम िझणकिu पर लजuि िरानॳ म अनदिलन दॳिा हॴ।

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78. In order to study the intracellular trafficking of protein ‘A’, it was tagged with GFP (A-GFP). Fluorescence microscopy showed that A-GFP co-localizes with LAMP1. In the presence of bafilomycin A, an inhibitor of H+-ATPase, A-GFP does not co-localize with LAMP1. Instead, it co-localizes with LC3 puncta.

Which one of the following statements is TRUE?

1. A-GFP targets to the ER in the absence of bafilomycin A.

2. Autophagy is required for trafficking of A-GFP to lysosomes.

3. Bafilomycin A facilitates targeting of A- GFP to the ER.

4. Bafilomycin A facilitates targeting of A- GFP to the mitochondria.

79. हररिलवि रिाuा िा सदमि ‘A’ हॴ। ‘A’ िॳ

भमलानॳ सॳ पवा ि ा प चाि रदीवपि हररिलवि म

O2 िा उ पादन एव ATP िा स लॳण तनब न दाााuॳ अनदसार मापा गuा।

िन-सा ि न सही हॴ?

1. NADP+ िी अपचuन िो ‘A’ सदभमि िरिा हॴ।

2. NADP+ िी अपचuन ि ा रोटॉन रवणिा िो ‘A’ सदभमि िरिा हॴ।

3. रोटॉन रवणिा िो ‘A’ सदभमि िरिा हॴ NADP+ अपचuन िो नही िरिा हॴ।

4. न िो रोटॉन रवणिा िो, न िो NADP+

अपचuन िो ‘A’ सदभमि िरिा हॴ।

79. ‘A’ is an inhibitor of chloroplast function. The

production of O2 and the synthesis of ATP are measured in illuminated chloroplasts before and after addition of ‘A’ as shown below

Which statement is correct? 1. ‘A’ inhibits the reduction of NADP+ 2. ‘A’ inhibits the proton gradient and the

reduction of NADP+ 3. ‘A’ inhibits the proton gradient but not

the reduction of NADP+

4. ‘A’ inhibits neither the proton gradient nor the reduction of NADP+

80. G1 सॳ S िि िॳ एि िोभािा चर रगमन िॳ दरान

साईस लीन D-CDK4, Rb िा फॉस फोररलीिरण िरिा हॴ ि ा E2F िॳ भलए उसिी बधदिा िो िम िरिा हॴ। Rb सॳ E2F अपघदटि होिा हॴ ि ा S-अवस ा जीन अभभ uजसि िो करuाजवि िरिा हॴ। रोटीन

‘A’ िी अतिअभभ uजसि G1 अवस ा रगमन िो रोि दॳिा हॴ। तनब न ि न म सॳ िन-सा सह हॴ?

1. Rb-E2F अ uो uकरuा िो ‘A’ सदभमि िरिा हॴ।

2. CDK4 तग िववतध िो ‘A’ सदभमि िरिा हॴ।

3. E2F िो ‘A’ फॉस फोररलीिि िरिा हॴ।

4. Rb िा अपिा ‘A’ िरिा हॴ।

80. During cell cycle progression from G1 to S,

cyclin D-CDK4 phosphorylates Rb and reduces its affinity for E2F. E2F dissociates from Rb and activates S-phase gene expression. Overexpression of protein ‘A’ arrests G1 phase progression.

Which of the following statements is TRUE? 1. ‘A’ inhibits Rb-E2F interaction 2. ‘A’ inhibits CDK4 activity 3. ‘A’ phosphorylates E2F 4. ‘A’ degrades Rb 81. िोभािा चर िी S-अवस ा िी िोभािाu, िोभािा

चर िॳ तनब न चरण िी िोभािाओ िॳ सा सलतuि िी गuी: (a) G1 अवस ा, (b) G2 अवस ा, (c)

M अवस ा। इन िोभािाओ िा वविास िप चाि दरटीिररि ाuभमडीन uदस ि मा uम म किuा गuा। S-अवस ा िोभािाओ म, जो तनब न सॳ सलतuि किuॳ गuॳ, नव लॳबभलि DNA िी उछ चिम मामा सभा u हॴ:

1. G1 अवस ा िोभािाu


3. M अवस ा िोभािाu

4. दोन G1 ि ा G2 अवस ा िोभािाu 81. Cells in S-phase of the cell cycle were fused to

cells in the following stages of cell cycle: (a) G1 phase, (b) G2 phase, (c) M phase. These cells were then grown in medium containing

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tritiated thymidine. Maximal amount of freshly labelled DNA is likely to be obtained in S-phase cells fused with

1. G1 phase cells 2. G2 phase cells 3. M phase cells 4. Both G1 and G2 phase cells 82. वविास िरिॳ E. coli िोभािाओ िॳ सा रतिजॴववि

सॳफालॳजससन िो भमलानॳ पर, िोभािाओ िा ििदलन हो जािा हॴ, िप चाि अपघटन। सॳफा लॳजससन इसिा एि सदमि हॴ

1. रोटीन स लॳण

2. DNA स लॳण

3. पॳजटडो लाईिन स लॳण

4. RNA पॉभलमरॳ 82. Addition of the antibiotic cephalexin to

growing E. coli cells lead to filamentation of the cells, followed by lysis. Cephalexin is an inhibitor of

1. protein synthesis 2. DNA synthesis 3. peptidoglycan synthesis 4. RNA polymerase 83. रतिदीजिि: लॳबभलि रोटीन, मीर म रोटीनराव

िॳ अ uuन िॳ भलए उपuोग म भलuा गuा। रतिदीजि तनब न म पाuी गई:

(a) गोल गी

(b) रावी पददटिा

(c) िठोर ER.

इन घटनाओ िॳ घटनॳ िॳ रम िा रॳ ठिम वणान तनब न म सॳ िन-सा िरिा हॴ?

1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a)

83. Fluorescently tagged protein was used to study

protein secretion in yeast. Fluorescence was observed in:

(a) the Golgi (b) the secretory vesicles (c) the rough ER. Which of the following describes best the

sequence in which these events occur? 1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a)

84. uह सदतनजचि िरनॳ िॳ भलए कि माम पणाि: ससातधि पररपस व mRNAs साईटोसॉल िि तनuााि होनॳ अनदमतिि ह, snRNPs िॳ सा सगि Pre -mRNAs

िरि म सदरषषि रखॳ जािॳ ह। इसॳ भसि िरनॳ िॳ भलए, एि रuोग किuा गuा जजसम एि pre-mRNA

िो िदरि िरनॳ वालॳ एि जीन िो, जजसिा माम एि इरान हॴ, uा िो 5 uा 3 समबधन स ल पर uा दोन समबधन स ल पर उ पररवतिाि किuा गuा।

िद ि सभा u पररणाम तनब नवि हॴ: A. बतधि snRNPs िी उपजस ति िॳ िारण दोन

समबधन स ल पर उ पररवतिाि Pre-mRNA

िरि म सदरषषि रखॳ जाएगॳ।

B. बतधि snRNPs िी अनदपजस ति िॳ िारण दोन समबधन स ल पर उ पररवतिाि Pre-mRNA साईटोसॉल िि तनuााि किuॳ जाuगॳ।

C. बतधि snRNPs िी उपजस ति िॳ िारण 3 uा 5 समबधन स ल पर उ पररवतिाि Pre-mRNA


D. बतधि snRNPs िी अनदपजस ति िॳ िारण 3 uा 5 समबधन स ल पर उ पररवतिाि Pre-mRNA

साईटोसॉल िि तनuााि किuॳ जाuगॳ।

सभा u पररणाम िॳ सही सuोजन िो चदन:

1. B ि ा C 2. A ि ा D

3. B ि ा D 4. A ि ा C 84. In order to ensure that only fully processed

mature mRNAs are allowed to be exported to cytosol, pre-mRNAs associated with snRNPs are retained in the nucleus. To demonstrate this, an experiment was performed where a gene coding a pre-mRNA with a single intron was mutated either at the 5 or 3 splice sites or both the splice sites.

Given below are a few possible outcomes: A. Pre-mRNA having mutation at both the

splice sites will be retained in the nucleus because of the presence of bound snRNPs.

B. Pre-mRNA having mutation at both the splice sites will be exported to cytosol because of the absence of bound snRNPs.

C. Pre-mRNA mutated at either 3 or 5 splice sites will be retained in the nucleus because of the presence of bound snRNPs.

D. Pre-mRNA mutated at either 3 or 5 splice sites will be exported to cytosol because of the absence of bound snRNPs.

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Choose the correct combination of the possible outcomes:

1. B and C 2. A and D 3. B and D 4. A and C 85. तनब न तचम म, िीन पररिाल पतनि अनदवाद सदमि िॳ

सा उपचाररि िोभािाओ िा पॉभलसोम पररछ िॳदन दाााuा गuा हॴ। uॳ िीन सदमि ह:

(i) CHP – अनदवाद िा टपििा सदमि

(ii) LTM – रारभन िोडान पर ररबोसोम िो रोििा हॴ।

(iii) PTM – ररबोसोम रमवीषण िो सदभमि िरिा हॴ।

पॉभलसोम पररछ िॳ ददिा िो सदमि िॳ सा सदमॳभलि िर:

1. (i) – a; (ii) – b; (iii) – c 2. (i) – b; (ii) – c; (iii) – a 3. (i) – c; (ii) – b; (iii) – a 4. (i) – a; (ii) – c; (iii) – b 85. Polysome profiling of cells treated with three

hypothetical translation inhibitors is shown in the plots below. These three inhibitors are

(i) CHP – leaky inhibitor of translation (ii) LTM – arrests ribosome at the initiation

codon (iii) PTM – inhibits ribosome scanning

Match the polysome profile to the inhibitor 1. (i) – a; (ii) – b; (iii) – c 2. (i) – b; (ii) – c; (iii) – a 3. (i) – c; (ii) – b; (iii) – a 4. (i) – a; (ii) – c; (iii) – b 86. स ितनu म, CG रचदर अनदरम सामा uि: C पर

मॴत लीिररि होिॳ ह, जो मनीिि जीन िो लॳबल िरनॳ िा एि िरीिा हॴ। uuवप रबधन जीन िॳ उ नाuि राu: CpG वीप िॳ सगि ह, ि ावप वॳ स ितनu म अभभ uस ि होिॳ ह। तनब न म सॳ िन-सा इसिी रॳ ठिम uा uा िरिा हॴ?

1. साईटोसीन िा मॴत लीिरण उ नाuि िॳ सा RNA Pol II िॳ बधन िो नही रोििा, अि: रबधन जीन अभभ uस ि किuॳ जािॳ ह।

2. रबधन जीन अभभ uजसि िॳ दरान, miRNA

वारा ए जाईम मॴत लरासफरॳ अस ाuी प म मनीिि होिा हॴ, इस रिार वॴजवि मॴत लन िो बध िरिॳ हदuॳ।

3. एि जीन िॳ िोडन षॳम िॳ अदर िॳ असा, सकरu जीन िॳ उ नाuि म उपजस ि CG -

रचदर अनदरम सामा uि: मॴत लीिररि नही होिॳ।

4. उ नाuि षॳम म साइटोसीन िी मॴत लीिरन होिॳ ही DNA षतिसदधार प िॳ ए ाईम मॴत ल समह िो तनिाल दॳिॳ ह, इस रिार जीन अभभ uजसि िो सदतनजचि िरिॳ हदए।

86. In mammals, CG rich sequences are usually

methylated at C, which is a way for marking genes for silencing. Although the promoters of housekeeping genes are often associated with CpG islands yet they are expressed in mammals. Which one of the following best explains it?

1. Methylation of cytosine does not prevent the binding of RNA Pol II with the promoter, so housekeeping genes are expressed

2. During housekeeping gene expression, the enzyme methyltransferase is temporarily silenced by miRNA, thus shutting down global methylation

3. Unlike within the coding region of a gene, CG rich sequences present in the promoters of active genes are usually not methylated

4. As soon as the cytosine is methylated in the promoter region, the enzymes of DNA repair pathways remove the methyl group, thereby ensuring gene expression

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87. टॳलोमॳरॳ, एि रोटीन-RNA सिद ल, िी एि ववभा ट उ रम राजसर टॳ गतिववतध हॴ जो DNA स लॳण िॳ दरान अ uाा िॳ रतिितिuन िो सपणा िरिी हॴ। uuवप उसिॳ िई गदणधमा DNA पॉभलमरॳ िॳ सा ह, िद ि भभ न भी ह। टॳलोमॳरॳ िॳ तनब न गदणधम म सॳ िन-सा DNA पॉभलमरॳ िॳ गदणधमा सॳ भभ न हॴ?

1. uजसलuोटाइड िॳ uोजन िो मागादभााि िरनॳ िॳ भलए टॳलोमॳरॳ िो एि दासा चादहuॳ।

2. टॳलोमॳरॳ DNA िॳ माम एि 3 -OH भसरॳ िो ववस िररि िर सििा हॴ।

3. टॳलोमरॳ प च र जदि स लॳण नही िरिा।

4. टॳलोमरॳ एि रकरuा मि िरीिॳ म िाम िरिा हॴ।

87. Telomerase, a protein-RNA complex, has a special reverse transcriptase activity that completes replication of telomeres during DNA synthesis. Although it has many properties similar to DNA polymerase, some of them are also different. Which one of the following properties of telomerase is different from that of DNA polymerase?

1. Telomerase requires a template to direct the addition of nucleotides

2. Telomerase can only extend a 3 -OH end of DNA

3. Telomerase does not carry out lagging strand synthesis

4. Telomerase acts in a processive manner 88. सदिरकिu म, रतिितिuन िॳ रारभन हॳिद भाररि

हॴभलिॳ स िो करuाजवि िरनॳ एि ववभा ट साईजसलन तनभार किनॳस (CDK) गतिववतध िी आव uििा हॴ। इसिॳ ववपरीि uह CDK गति ववतध रतिितिuन िी मलबदद पर हॴभलिॳ स िॳ सभारण िो सदभमि िरिा हॴ। इस वास िववििा पर ववचारिॳ हदuॳ कि हर चर िॳ दरान, मलबदद पर सभाररि होनॳ िॳ भलए हॴभलिॳ स िॳ पास एि ही मिा हॴ ि ा इन भाररि हॴभलिॳ स िो करuाजवि होनॳ िॳ भलए माम एि मिा हॴ, तनब न आलॳख म सॳ िन-सा िोभािा चर िॳ G1 ि ा S अवस ाओ म इस CDK गतिववतध िो रॳ ठि म दााािा हॴ?

88. In eukaryotes, a specific cyclin dependent

kinase (CDK) activity is required for the activation of loaded helicases to initiate replication. On the contrary, this CDK activity inhibits the loading of helicases onto the origin of replication. Considering the fact that during each cycle, there is only one opportunity for helicases to be loaded onto origins and only one opportunity for these loaded helicases to be activated, which one of the following graphs best depicts this CDK activity in G1 and S phases of the cell cycle?

89. राईपनोसोम म, एि 35 षार रॳिा अनदरम िई

भभ न अनदलॳख िॳ सा जोाा जािा हॴ, िाuााील mRNAs िो बनािॳ हदuॳ। नॳिा अनदरम अ u RNAs

िॳ सा इस वारा जोाा जािा हॴ:

1. एि ववभा ट RNA लाइगॳ

2. पार-समबघन िी रकरuा

3. एि मदस ि गदआतनन uजसलuोटाईड सॳ िारझणि एि िरिानदरागी आरमण

4. नॳिा अनदरम म उपजस ि एि आिररि A िॳ एि 2 OH सॳ िारझणि एि िरिानदरागी आरमण

89. In Trypanosomes, a 35 base leader sequence is

joined with several different transcripts making functional mRNAs. The leader sequence is joined with the other RNAs by

1. a specific RNA ligase 2. the process of trans-splicing 3. a nucleophilic attack caused by a free

guanine nucleotide 4. a nucleophilic attack caused by a 2 OH of

an internal A present in the leader sequence

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90. िद ि ववितिजन स िभ A म ि ा स िभ B म रतिरषी अनदकरuा सॳ बचनॳ िॳ भलए उनसॳ उपuोग म भलए जानॳ वालॳ िद ि अवविीu ररम तनब नवि सचीिि ह:

A B a. Trypanosoma

brucei (i) असाधारण जीन

रकरuाओ िो उपuोग िरनॳ िी षमिा, जजससॳ वॳ अपनॳ पररविी सिही गलाuिो-रोटीन (VSG) म ववस िि पररविान जतनि िरिॳ ह

b. Plasmodium falciparum

(ii) ववभभ न प म पािरण िॳ दरान सिि पररपस विा पररविान अनदभव िरनॳ िी षमिा, जो जीव िो अपनॳ सिही अणदओ िो बदलनॳ दॳिा हॴ।

c. Haemophilus influenzae

(iii) अपनॳ हॴम गलदटतनन ि ा uरोभमतनडॳस लाईिोरोटीन म बार-बार रतिजनी पररविान िरिॳ रतिरषी अनदकरuा सॳ बचनॳ िी षमिा

तनब न म सॳ िन-सा सही हॴ, जीव ि ा अपनॳ सगि ररम िा, िाकि रतिरषी अनदकरuा सॳ बचाuा जा सििा हॴ?

1. a – (i), b – (ii), c – (iii)

2. a – (ii), b – (iii), c – (i)

3. a – (iii), b – (i), c – (ii)

4. a – (i), b – (iii), c – (ii)

90. Following are the list of some of the pathogens (column A) and the unique mechanisms they employ for evading immune response (column B).

A B a. Trypanosoma

brucei (i) Capable of employing

unusual genetic processes by which they generate extensive variations in their variant surface glycoproteins (VSG)


(ii) Capable of continua-lly undergoing maturational changes in transformation to different forms which allow the organism to change its surface molecules


(iii) Capable of evading immune response by frequent antigenic changes in its hemagglutinin and neuraminidase glycoproteins

Which of the following is the correct match

between the organisms and their respective mechanism to evade immune response?

1. a – (i), b – (ii), c – (iii) 2. a – (ii), b – (iii), c – (i) 3. a – (iii), b – (i), c – (ii) 4. a – (i), b – (iii), c – (ii) 91. दो स टॴराइा हामोन रादहu X ि ा Y म एि सल नी

आबधन षॳम ि ा एि DNA आबधन षॳम उपजस ि ह। पदनuोगज DNA ििनीिी िॳ उपuोग सॳ एि पररवतिाि हाईरा राही H िॴuार किuा जािा हॴ िाकि उसम X िा सल नी आबधन षॳम ि ा Y िा

DNA आब धन षॳम उपजस ि ह। िप चाि रादहu X, Y ि ा H िो अतिअभभ uस ि िरिी िोभािाओ िॳ िीन समदछ चu िो अलग सॳ हामोन X uा हामोन Y िॳ सा उपचार किuा गuा। uह मानिॳ हदए कि िोई तिuाि-अभभकरuिा नही हॴ, तनब न आलॳख म सॳ िन-सा, हर ववu म राही-सल नी आबधन िा रॳ ठिम रतितनतध व िरिा हॴ?

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91. Two steroid hormone receptors X and Y both contain a ligand binding domain and a DNA binding domain. Using recombinant DNA technology, a modified hybrid receptor H is prepared such that it contains the ligand binding domain of X and DNA binding domain of Y. Three sets of cells over-expressing receptors X, Y and H were then treated separately either with hormone X or with hormone Y. Assuming that there is no cross-reactivity, which one of the following graphs best represent the receptor-ligand binding in each case?

92. रोटीन Y िॳ सा सिद भलि िरिॳ साईटोसॉल म एि

रोटीन X िो सकरu अवस ा म रखा जािा हॴ। किसी रतिबल उ िॳजन िॳ अधीन, Y फॉस फोररभलि हो जािा हॴ, ि ा उसिा रोदटuोसोमल अविा हो जािा हॴ। X मदस ि हो जािा हॴ, िरि म स ानािररि हो जािा हॴ, ि ा एपो टोभसस वारा िोभािा म uद िरनॳवालॳ जीन िॳ अनदलॳखन म पररणभमि होिा हॴ। तनब न चार अलग ववu म रतिबल उ िॳजन ददuा गuा:-

ववषय A: रोटीन Y िा एि उ पररविान हॴ िाकि रोदटuोसोमल अविा पर लॳ जानॳ वाला फॉस फोररलीिरण नही घटिा।

ववषय B: रोटीन Y िो िरि िि स ानािररि होनॳ िो सदभमि िरिॳ एि रोटीन L िो िोडडि िरनॳ वालॳ एि जीन िॳ सा िोभािाu पारसरभमि िी जािी ह।

ववषय C: िोभािाu माम एि ररस ि वाहि, जो रोदटन L िॳ भलए जीन िो पारसरभमि िरनॳ म िाम आिा हॴ, िॳ सा पारसरभमि िी जािी ह।

ववषय D: िोभािाओ िो Z-VAD-FMK, जो एि ववस िि स पॴस रम िॴ पॳस सदमि हॴ, िॳ सा उपचाररि किuा जािा हॴ।

तनब न आलॳख म सॳ िन-सा उपरोस ि ववu म िोभािाओ िी एपो टोदटि जस ति िा रॳ ठिम वणान िरिा हॴ? Y-अष % एपो टोदटि िोभािाओ िा रतितनतध व िरिा हॴ।

92. A protein X is kept in an inactive state in

cytosol as complexed with protein Y. Under certain stress stimuli, Y gets phosphorylated resulting in its proteasomal degradation. X becomes free, translocates to nucleus and results in the transcription of a gene which causes cell death by apoptosis. Stress stimuli were given to following four different cases.

Case A: Protein Y has a mutation such that phosphorylation leading to proteasomal degradation does not occur.

Case B: Cells are transfected with a gene which encodes for a protein L that inhibits the translocation of protein Y to the nucleus.

Case C: Cells are transfected only with empty vector used to transfect the gene for protein L.

Case D: Cells are treated with Z-VAD-FMK, a broad spectrum caspase inhibitor.

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Which one of the following graphs best describes the apoptotic state of the cells in the above cases? Y-axis represents % apoptotic cells.

93. स िभ A म, राझणu म िोभािा-िोभािा आसजन

रोटीन िॳ चार अलग िद टद ब सतचि ह, ि ा उनिॳ रिाuी लषण स िभ B म ददuॳ गuॳ ह।

A B

a. इटॳतरन (i) रस ि सररिा म ववभभ न न वर, िोभािा-िोभािा आसजन अ uो uकरuाओ िो माजuि िरनॳवालॳ लॴजसटन

b. िॴ ढॳररन (ii) बाuिोभािाई Ig-जॴसॳ षॳम रखिा हॴ ि ा रमदखि: वविास ि ा पदनजानन िॳ दरान िोभािा-िोभािा आसजन अ uो uकरuाओ िॳ स म-समस वरण िरनॳ म सजबमभलि ह।

c. Ig-अतध

िद टद ब

(iii) Ca2+- तनभार रबल होमोक फभलि िोभािा-िोभािा आसजन िो माजuि िरिा हॴ

d. सॳलॳजसटन (iv) पार-झिल ली िोभािा आसजन रोटीन जो बाuिोभािाई आधामी रादहu जॴसॳ िाम िरिॳ ह।

तनब न म सॳ िन-सा सही सuोजन हॴ? 1. a – (i), b – (ii), c – (iii), d – (iv) 2. a – (ii), b – (iii), c – (iv), d – (i) 3. a – (iii), b – (iv), c – (i), d – (ii) 4. a – (iv), b – (iii), c – (ii), d – (i) 93. In animals, four separate families of cell-cell

adhesion proteins are listed in Column A and their functional characteristics are given in Column B.

A B

a. Integrin (i) Lectins that mediate a variety of transient, cell-cell adhesion interactions in the blood stream

b. Cadherin (ii) Contains extracellular Ig-like domains and are mainly involved in the fine tuning of cell-cell adhesive interactions during development and regeneration.

c. Ig-super- family

(iii) Mediates Ca2+- depen-dent strong homophilic cell-cell adhesion.

d. Selectin (iv) Transmembrane cell adhesion proteins that act as extracellular matrix receptors

Which one of the following is the correct

combination? 1. a – (i), b – (ii), c – (iii), d – (iv) 2. a – (ii), b – (iii), c – (iv), d – (i) 3. a – (iii), b – (iv), c – (i), d – (ii) 4. a – (iv), b – (iii), c – (ii), d – (i) 94. एि ववuा ी नॳ िसर िोभािाओ िा उपचार एि

रति-िसर औतध सॳ किuा ि ा वॳस टना ाॳण वव लॳण किuा। अनदपचाररि तनuमण (C) ि ा उपचाररि (T) नमन िा रॳ ठिम रतितनतध व तनब न ाोण म िन-सा िरिा हॴ?

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94. A student treated cancer cells with an anti-

cancer drug and performed western blot analysis. Which one of the following blots is the best representation of untreated control (C) and treated (T) samples?

95. B िोभािा राही (BCR) ि ा T िोभािा राही (TCR)

िॳ बारॳ म किuॳ गuॳ तनम न ि न म सॳ िन-सा सही नह हॴ ?

1. TCR झिल ली िॳ सा बतधि हॴ ि ा BCR जॴसॳ ववलॳu प म रिट नही होिा।

2. BCR सॳ असा, अतधिाा TCR रतिजन माम िॳ भलए ववभा ट नही होिॳ, परिद MHC

uदस ि रतिजन िॳ भलए ववभा ट ह।

3. सिॳ ि पाररमण िो िाuााजवि िरनॳ िॳ भलए BCR, Ig-α/Ig- िॳ सग हो जािा हॴ, जबकि TCR, CD3 िॳ सग होिा हॴ।

4. TCR िी अपॳषा BCR िी रतिजन बधन अ uो uकरuाu िही अतधि ददबाल ह।

95. Which one of the following statements regarding

B cell receptor (BCR) and T cell receptor (TCR) is NOT true?

1. TCR is membrane bound and does not appear as soluble form as does the BCR

2. Unlike BCR, most of the TCR are not specific for antigen alone but for antigen combined with MHC

3. In order to activate signal transduction, BCR associates itself with Ig-α/Ig- whereas TCR associates with CD3

4. The antigen binding interactions of BCR is much weaker than TCR

96. उभuचर िॳ ववu म, प ठeu ओ ठ िोभािाu ि ा

उनि सजाि “स पॳमन-मानगोल ा uवस ापि” िहलािॳ ह। “ uवस ापि” सॳ सबतधि तनब न ि न किuॳ गuॳ:

A. वह आति ॳu िॳ अधर ऊिि िो अपनॳ भा u बदलनॳ िॳ भलए रॳररि िरिा हॴ, एि िमिा नभलिा एव प ठeu म uचमी ऊिि बनानॳ।

B. वह आति ॳu ि ा दािा ऊिि िो एि वविीuि रण म uवजस ि नही िर सििा।

C. अधर म uचमा म स व-ववभॳददि होनॳ िी षमिा उसम नही हॴ।

D. िददिन गतिाीलिा िो रारभभि िरनॳ िी षमिा उसम हॴ।

E. uवस ापि वारा -िॴ टॳतनन ि ा िोडड ान, दोन उ पाददि होिॳ ह।

उपरोस ि ि न िॳ तनब न सuोजन म सॳ िन-सा सही ह?

1. A ि ा D 2. D ि ा E

3. A ि ा E 4. B ि ा C

96. In case of amphibians, the dorsal lip cells and

their derivatives are called as “Spemann - Mangold organizer”. Following statements related to the “organizer” were made:

A. It induces the host’s ventral tissues to change their fates to form a neural tube and dorsal mesodermal tissues.

B. It cannot organize the host and donor tissues into a secondary embryo.

C. It does not have the ability to self- differentiate into dorsal mesoderm.

D. It has the ability to initiate the movements of gastrulation.

E. Both -catenin and Chordin are produced by the organizer.

Which of the above statements are correct? 1. A and D 2. D and E 3. A and E 4. B and C 97. डरuॳा नॳ रभसि “दाब लॴट” रuोग किuा जजसम 8-

िोभािी समदरी अतचान रण िॳ सा जदटल पदनuोजन सजबमभलि ा। uह ववतध साधारणि: अि चमा बनानॳ िॳ भलए भाजuि षॳम म रहिॳ िरि िो अनदमातनि बदह चमा षॳम िॳ अदर अदल-

बदल िरिी ी। uदद िरिीu तनणााuि िा

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अलगीिरण घदटि हदआ, पररणभमि रण िो अ uवजस ि होना चादहए। परिद डरuॳा नॳ इन रण सॳ सामा u डडभि पाuॳ। सभा u uा uाu ह:

A. एि ववलतगि िोरिखड िी भावी ाजसि उसिॳ अपनॳ वास िववि भावी भा u सॳ अतधि हॴ।

B. िोरिखड िी भावी ाजसि ि ा भावी भा u सवा ासमान ॳ।

C. समदरी अतचान रण एि “सदसगि: समववभव िम” हॴ स uकि उसिॳ सभी सभा uि: स विम भाग नॳ एि एिल रण बनानॳ िॳ भलए सा म अ uो uकरuा िी।

D. जहा रण म स ान, एि िोभािा तनuति तनधााररि िरिा हॴ, तनuम मि वविास घदटि होिा हॴ।

उपरोस ि uा uाओ म िन-सा/सॳ सही हॴ/ह?

1. माम A 2. माम D

3. माम A ि ा B 4. A, C ि ा D 97. Driesch performed the famous “pressure plate”

experiment involving intricate recombination with an 8-celled sea urchin embryo. This procedure reshuffled the nuclei that normally would have been in the region destined to form endoderm into the presumptive ectoderm region. If segregation of nuclear determinants had occurred, the resulting embryo should have been disordered. However, Driesch obtained normal larvae from these embryos. The possible interpretations regarding the 8-celled sea urchin embryo are:

A. The prospective potency of an isolated blastomere is greater than its actual prospec tive fate.

B. The prospective potency and the prospective fate of the blastomere were identical.

C. Sea-urchin embryo is a “harmoniously equipotential system” because all of its potentially independent parts interacted together to form a single embryo.

D. Regulative development occurs where location of the cell in the embryo determines its fate.

Which of the above interpretation(s) is/are true? 1. Only A 2. Only D 3. Only A and B 4. A, C and D 98. समदरी अतचान अड िॳ तनॳचन िॳ दरान घटनॳवाली

तनब न घटनाओ पर ववचार:

A. रीसॴस ट/स पॴरास ट अाा जॳली सॳ मदजसिि पॳ टाईा ह ि ा वॳ ादराणद आिाण म सहाuिा िरिॳ ह।

B. बडडन, जो एि अरवपडिीu रोटीन हॴ, अा ि सा एि रजाति-ववभा ट िरीिॳ सॳ अ uो uकरuा िरिी हॴ।

C. तनॳचन आवरण िॳ तिuाि -बधन िॳ दरान एि

“ वसन रस फोट” घदटि होिा हॴ, जहा एि िॴ जलाuम-तनभार ववि ऑस सीजन स िर म रॳषषि होिा हॴ।

D. IP3, जो ादराणद िॳ आगमन बदद पर बनिा हॴ, िॴ जलuम जमा िरिा हॴ जो वलिद टी िझणिा बदह:िोभाििा म पररणभमि होिा हॴ।

उपरोस ि ि न म िन-सा सही नह हॴ?

1. माम C 2. A ि ा C

3. माम D 4. B ि ा D 98. Consider the following events which occur

during fertilization of sea urchin eggs. A. Resact/Speract are peptides released from the

egg jelly and help in sperm attraction. B. Bindin, an acrosomal protein, interacts in a

species-specific manner, with eggs. C. A “respiratory burst” occurs during cross-

linking of the fertilization envelope, where a calcium-dependent increase in oxygen levels is observed.

D. IP3, which is formed at the site of sperm entry, sequesters calcium leading to cortical granule exocytosis.

Which of the above statement(s) is NOT true? 1. Only C 2. A and C 3. Only D 4. B and D 99. स िनी रण िॳ वविास िॳ दरान भलuॳ जानॳ वालॳ

तनणाu िॳ बारॳ म तनब न ि न ददuॳ गuॳ।

A. आिररि िोभािा र uभार (ICM) िी अनॳिाजसि िीन अनदलॳखन िारि Oct 4, Sox 2 ि ा Nanog िॳ एि रोा सॳ बनाuॳ रखी जािी हॴ।

B. िोरिपदटी सरचना सॳ पवा, हर िोरिखड दोन Cdx 2 ि ा Oct 4 अनदलॳखन िारि िो अभभ uस ि िरिा हॴ ि ा ICM uा पोिोरि बननॳ म सषम रिीि होिा हॴ।

C. ICM ि ा पोिोरि िोभािाu, दोन अनदलॳखन िारि Cdx 2 िा स लॳण िरिॳ ह।

D. Cdx 2 अभभ uजसि िो Oct 4 करuावव ि िरिा हॴ, िद ि िोभािाओ िो पोिोरि ि ा अ u िोभािाओ िो ICM बननॳ uो u िरिॳ हदuॳ।

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उपरोस ि ि न िॳ तनब न सuोजन म स िन-सा सही हॴ?

1. A ि ा B 2. A ि ा C

3. B ि ा D 4. B ि ा C 99. Following statements were given regarding the

decisions taken during the development of mammalian embryos:

A. The pluripotency of the inner cell mass (ICM) is maintained by a core of three transcription factors, Oct 4, Sox 2 and Nanog.

B. Prior to blastocyst formation each blastomere expresses both Cdx 2 and the Oct 4 transcription factors and appears to be capable of becoming either ICM or trophoblast.

C. Both ICM and trophoblast cells synthesize transcription factor Cdx 2.

D. Oct 4 activates Cdx 2 expression enabling some cells to become trophoblast and other cells to become ICM.

Which of the above statements are true? 1. A and B 2. A and C 3. B and D 4. B and C

100. ववभभनन सरचनाओ िॳ सही रचना िॳ भलए रारभभि वविास िॳ दरान एपॳ टोभसस अतनवाuा हॴ। C.

elegans म एपो टोभसस ced-3 ि ा ced-4 जीन सॳ रबभलि किuा जािा हॴ, जो आगॳ ced-9 सॳ ऋणि: तनuमि ह ि ा अिि: EGL-1 सॳ। स ितनu िी िदलना म, रिाuाि: सा समजाि िी पहचान िी गई हॴ। इसिॳ अनदसार तनब न ि न म सॳ िन-सा सही नह हॴ?

1. CED-4, Apaf -1 सॳ साब u रखिा हॴ।

2. CED-9, Bcl-XL सॳ साब u रखिा हॴ।

3. CED-3, caspase-3 सॳ साब u रखिा हॴ। 4. CED-4, caspase-9 सॳ साब u रखिा हॴ।

100. Apoptosis during early development is essential

for proper formation of different structures. In C. elegans, apoptosis is accentuated by ced-3 and ced-4 genes, which in turn are negatively regulated by ced-9 and eventually EGL-1. When compared to mammals, functionally similar homologues have been identified. Accordingly, which one of the following statements is NOT correct?

1. CED-4 resembles Apaf -1 2. CED-9 resembles Bcl-XL 3. CED-3 resembles caspase-3 4. CED-4 resembles caspase-9

101. पद पाग वविास िॳ रतिमान िो पद प िॳ आस न चस िर म समापवधी जीन िी uजसिगि एव आछ िाददि अभभ uजसि तनधााररि िरिी हॴ। एि एराबडोजसस उ पररविी म पद पाग तनब नवि बदटि ह:

चस स र 1 (बाuिम) – अडप

चस स र 2 – पदिॳ सर


चस स र 4 (अिस िम) – अडप

तनब न जीन म सॳ किसम हदuॳ रिाuा-षति उ पररविान नॳ, उपरोस ि पद पाग वविास रतिमान िो िारझणि किuा होगा?

1. APETALA 2 2. APETALA 3 3. PISTILLATA 4. AGAMOUS

101. Individual and overlapping expression of homoeotic genes in adjacent whorls of a flower determine the pattern of floral organ development. In an Arabidopsis mutant, floral organs are distributed as follows:

Whorl 1 (outer most) – carpel Whorl 2 – stamens Whorl 3 – stamens Whorl 4 (inner most) – carpel Loss of function mutation in which one of the

following genes would have caused the above pattern of floral organ development?


102. रिाास लॳी इलॴस रॉन पररवहन म, इलॴस रॉन “Z-

स िीम” म uवजस ि वाहि िॳ ररuॳ uािाuाि िरिॳ ह। इलॴस रॉन वाह िी ददााu तनब नवि इतगि ह:

A. B. C. D.

तनब न सuोजन म सॳ िन-सा सही हॴ?

1. A ि ा B 2. B ि ा C

3. C ि ा D 4. A ि ा D

102. In photosynthetic electron transport, electrons

travel through carriers organized in the “Z-scheme”. The following are indicated as directions of electron flow:

A. B. C. D.

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Which one of the following combinations is correct?

1. A and B 2. B and C 3. C and D 4. A and D

103. रिाा सरचनावविास िा पादपवणाि माजuि तनuमण िई अ u जीन रिाu सॳ सबतधि हॴ। पादपवणाि िाuा िॳ ररम िॳ बारॳ म तनब न ि न किuॳ गuॳ ह:

A. पादपवणाि रिाuा िॳ भलए COP1, एि E3

uदबजसवदटन भलगॳस जो रोटीन अविा िरिा हॴ, िी आव uििा हॴ।

B. रिाा िी उपजस ति म COP1 िा धीरॳ-धीरॳ िरि सॳ िोभािा र u िि तनuााि किuा जािा हॴ।

C. रिाा िी उपजस ति म अपिा िॳ भलए COP1 वारा HY5 लजuि होिा हॴ।

D. रिाासरचनावविासी रतिकरuा म सजबमभलि एि अनदलॳखन िारि HY5 हॴ।


1. A, B ि ा C 2. B, C ि ा D

3. A, B ि ा D 4. A, C ि ा D

103. Phytochrome-mediated control of photomor-

phogenesis is linked to many other gene functions. The following statements are made on the mechanism of phytochrome action:

A. Phytochrome function requires COP1, an E3 ubiquitin ligase that brings about protein degradation

B. COP1 is slowly exported from the nucleus to the cytoplasm in the presence of light

C. HY5 is targeted by COP1 for degradation in the presence of light

D. HY5 is a transcription factor involved in photomorphogenetic response


1. A, B and C 2. B, C and D 3. A, B and D 4. A, C and D

104. C4 िॉबान चर एि CO2 सारण िरिा ररम हॴ जो रिाा वसन िो िम िरनॳ वविभसि हदआ। C4 प िॳ िद ि मह वपणा पहल तनब नवि ित ि ह:

A. C4 पादप िॳ पणा र ाारीर रखिॳ ह, जो पणाम uोिि ि ा पलाछ िद िोभािाओ म भॳद िरिा हॴ।

B. पररधीu पणाम uोिि िोभािाओ म फॉस फोईनाल पाईवॳट िॉबााजससलॳस वारा वाuदमडलीu CO2

जस रीिररि हो हॴ, एि चार िॉबान अब ल दॳिॳ हदuॳ।

C. पणाम uोिि िॳ आिररि परि म चार िॉबान अब ल िो NAD-मॴभलि ए ाईम वविॉबााजससलीिरण िरिॳ CO2 िो मदस ि िरिा हॴ।

D. CO2 कफर सॳ पलाच िद िोभािाओ म िॴ जलवन चर वारा पदन:जस रीिररि होिा हॴ।


1. B, C ि ा D 2. A, B ि ा C

3. A, B ि ा D 4. A, C ि ा D

104. The C4 carbon cycle is a CO2 concentrating mechanism evolved to reduce photorespiration. The following are stated as important features of the C4 pathway:

A. The leaves of C4 plants have Kranz anatomy that distinguishes mesophyll and bundle sheath cells.

B. In the peripheral mesophyll cells, atmospheric CO2 is fixed by phosphoenol pyruvate carboxy- lase yielding a four-carbon acid.

C. In the inner layer of mesophyll, NAD-malic enzyme decarboxylates four-carbon acid and releases CO2.

D. CO2 is again re-fixed though Calvin cycle in the bundle sheath cells.

Which one of the following combinations is

correct? 1. B, C and D 2. A, B and C 3. A, B and D 4. A, C and D

105. पादप-रोगजनि अ uो uकरuा सॳ सबतधि तनब न ि न िो पढ:

A. सदसगि रोगजनि सॳ सरमण िॳ उपराि अवा ि िमि रतिरोध दॳखा जािा हॴ।

B. सदसगि रोगजनि सॳ सरमण िॳ उपराि, रॳररि िमि रतिरोध करuाजवि होिा हॴ।

C. जीवाणद सरमण, रभावी रवतिाि रतिरषा (ETI)

िो रॳररि िर सििा हॴ, स ानीu अतधसवॳदनीu अनदकरuा पर लॳ जािॳ हदuॳ।

D. सॴभलभसभलि अब ल िॳ सरहण िॳ िारण साईटोसॉल म मदजसिि NPR1 मॉनोमर िरि िि ाीरि: स ानािररि होिॳ ह।

उपरोस ि ि न िा िन-सा सuोजन सही हॴ?

1. A, B ि ा C

2. A, C ि ा D

3. A, B ि ा D

4. B, C ि ा D

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105. Read the following statements related to plant-pathogen interaction

A. Systemic acquired resistance is observed following infection by compatible pathogen B. Induced systemic resistance is activated following infection by compatible pathogen C. A bacterial infection can induce effector triggered immunity (ETI) leading to hypersensitive response locally D. NPR1 monomers that are released in cytosol due to salicylic acid accumulation is rapidly translocated to nucleus

Which combination of above statements is correct?

1. A, B and C 2. A, C and D 3. A, B and D 4. B, C and D

106. पादप म ववलॳu पररवहन ि ा रिाा स वागीिरण िॳ ववभभ न पहलदओ िा वणान िरिॳ ि न तनब न ददuॳ गuॳ ह।

A. जीवर uि वी सपिा हीन िोभािाओ िॳ बीच अपसदघदटि पोवाही भारण घदटि होिा हॴ।

B. वविासाील िातuि अभभगम (उदा. िण पणा एव मल) सामा uि: ससदघदटि पोवाही ववभारण अनदभव िरिॳ ह।

C. माम रोि ि ा अभभगम षॳम म पोवाह एव दा िॳ बीच जल िी गतिाीलिा घटिी हॴ।

D. जीवर uि वी सपिा िी अनदपजस ति म पोवाह िॳ अदर ास िर िा ससदघदटि भारण घटिा हॴ।

सही ि न िॳ एि सuोजन दॳनॳवालॳ वविल प िो चदन:

1. माम A ि ा C 2. माम B ि ा C

3. माम B ि ा D 4. माम A ि ा B

106. Given below are statements describing various

features of solute transport and photoassimilate translocation in plants.

A. Apoplastic phloem loading of sucrose happens between cells with no plasmodesmatal connections

B. Growing vegetative sinks (e.g., young leaves and roots) usually undergo symplastic phloem unloading

C. Movement of water between the phloem and xylem occurs only at the source and sink regions

D. Symplastic loading of sugars into the phloem occurs in the absence of plasmodesmatal connections

Select the option that gives a combination of correct statements:

1. Only A and C 2. Only B and C 3. Only B and D 4. Only A and B

107. पादपहामोन िॳ नाम स िभ I म ि ा उनसॳ सगि पहल/रभाव/रिाuा स िभ II म तनब न ददuॳ गuॳ ह

I II

A ऑस सीन (i) ववलबि पणा जीणािा

B तग बॳरॳल लीनस (ii) पण िा अधोिद चीu नमन

C साईटोिाईनीन (iii) रदवीu पररवहन

D ऐत लीन (iv) बीज रसदजि िा अपादान

तनब न ददuॳ गuॳ वविल प सॳ सuोजन िॳ सही समदछ चu िो चदन:

1. A – (iii), B – (ii), C – (iv), D – (i) 2. A – (iv), B – (iii), C – (i), D – (ii) 3. A – (iii), B – (iv), C – (i), D – (ii) 4. A – (i), B – (iv), C – (iii), D – (ii)

107. Given below are names of phytohormones in column I and their associated features/effects/ functions in column II.

I II

A Auxin (i) Delayed leaf senescence

B Gibberellins (ii) Epinastic bending of leaves

C Cytokinin (iii) Polar transport D Ethylene (iv) Removal of seed

dormancy Select the correct set of combinations from the

options given below: 1. A – (iii), B – (ii), C – (iv), D – (i) 2. A – (iv), B – (iii), C – (i), D – (ii) 3. A – (iii), B – (iv), C – (i), D – (ii) 4. A – (i), B – (iv), C – (iii), D – (ii)

108. uदद किसी रस िाधान म A वगा िा दािा रस ि, B वगा रस ि वालॳ राही िो ददuा जािा हॴ िो दािा रस ि िी लाल रस ि िोभािाu (RBCs) आजल ट होिी ह, परिद राही िॳ RBCs uनिम रभाववि हगी। uॳ रॳषण तनब न ि न म uाजuि हो सििॳ हॴ:

A. राही िॳ लाामा िॳ अगलदटतनन, वगा A

आ लॳजन िॳ सा बाधिर आ लॳण िारझणि िरिॳ ह।

B. दािा रस ि िॳ अगलदटतनन राही िी लाामा म िनिररि हदuॳ, अल प आ लॳण म पररणभमि ।

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C. राही िॳ RBCs िॳ अल प आ लॳण िा रति-A

अगलदटतनन िॳ अल प अनदमाप िारण हॴ।

D. दािा RBCs िा उछ च आ लॳण रति-B

अगलदटतनन िॳ उछ च अनदमाप िा पररणाम हॴ।

उपरोस ि ि न म सॳ िन-सा/सॳ गलत हॴ/ह?

1. माम A 2. A ि ा B

3. माम B 4. C ि ा D

108. If in a blood transfusion, type A donor blood is

given to a recipient having type B blood, the red blood cells (RBCs) of donor blood would agglutinate but the recipient’s RBCs would be least affected. These observations can be explained in the following statements:

A. Agglutinins in recipient’s plasma caused agglutination by binding with type A agglutinogens

B. The agglutinins of donor blood was diluted in recipient’s plasma resulting in low agglutination

C. Low titre of anti-A agglutinins is the cause of low agglutination of recipient’s RBCs

D. High agglutination of donor RBCs is the outcome of high titre of anti-B agglutinins

Which of the above statement(s) is/are INCORRECT ?

1. Only A 2. A and B 3. Only B 4. C and D

109. सामा uि: धमनीu दाब 4 सॳ 6 mm Hg एि िरग जॴसॳ िरीिॳ सॳ उिलिा ि ा तगरिा हॴ, धमनीu दाब म “ वसन िरग” िो िारझणि िरिॳ हदए। इन िरग िा सभा u ररम तनब न ि न म रस िाववि हॴ:

A. अि: वसन िॳ दरान अतधि ऋण आिरवषीu दाब दu िॳ वाम भाग पर वापस आिॳ रस ि िी मामा िो िम िरिा हॴ, षतuि दीu तनगाि िो िारझणि िरिॳ ।

B. वसन िॳ दरान आिरवषीu दाब म होिॳ पररविान सवहनी ि ा पररिो ठe ववस िरण रादहu िो उ िॳजजि िर सििॳ ह, जो दuी ि ा रस ि वादहिाओ िो रभाववि िरिॳ ह।

C. म जा वसनी रद िी गतिववतध वादहिारॳरि िर िो रभाववि िर सििी हॴ।

D. िरीu िमिी िम िॳ स ातनि रस ििीu दाब तनuमण ररम िॳ दोलन िा पररणाम हॴ

“ वसनीu िरग” ।

उपरोस ि ि न म िन-सा/सॳ उपuदस ि नह हॴ/ह?


3. B ि ा C 4. माम D

109. The arterial pressure usually rises and falls 4 to

6 mm Hg in a wave like manner causing “respiratory waves”. The probable mechanism of these waves has been proposed in the following statements:

A. The more negative intrathoracic pressure during inspiration reduces the quantity of blood returning to the left side of the heart causing decreased cardiac output.

B. The changes of intrathoracic pressure during respiration can excite vascular and atrial stretch receptors which affect heart and blood vessels.

C. The activity of medullary respiratory centres can influence the vasomotor centre.

D. The “respiratory waves” are outcome of the oscillation of the central nervous system ischemic pressure control mechanism.

Which of the above statement(s) is/are NOT appropriate?

1. Only A 2. A and B 3. B and C 4. Only D

110. तनब न तचम म, फॳ फाा िवपिा िॳ भािा िॳ रस ि म नाईरस ऑस साईा (N2O) ि ा िॉबान मॉनोस साईा (CO) िा उरहण उनिॳ आभाि दाब िॳ सापॳष ि ा िॳ भािा म लाल रस ि िोभािा िा पारगमन समu ददखाuॳ गuॳ ह:

तनब न ि न म N2O ि ा CO िॳ िवपिा गॴस ववतनमu रतिमान म भॳद िॳ िारण रस िाववि किuॳ गuॳ ह:

A. रस ि म रोटीन िॳ सा N2O रासाuतनिि: सuोजजि नही होिा, परिद रस ि ि ा िवपिा गॴस िॳ बीच वह ाीरि: साब uावजस ि होिा हॴ।

B. रस ि म CO िी उछ च ववलॳuिा हॴ।

C. िवपिा िॳ भािा झिल ली म CO िी उछ च ववलॳuिा हॴ।

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D. िवपिा गॴस ि ा रस ि िॳ बीच N2O िा ववषॳपण ववसरण-पररबतधि माना जािा हॴ।



3. माम C 4. C ि ा D

110. The uptake of nitrous oxide (N2O) and carbon

monoxide (CO) in the blood of lung alveolar capillary relative to their partial pressure and the transit time of red blood cell in capillary is shown in the figure below:

The reasons for difference in the pattern of

alveolar gas exchange of N2O and CO have been proposed in the following statements:

A. N2O does not chemically combine with proteins in blood but equilibrate rapidly between alveolar gas and blood

B. CO has high solubility in blood C. CO has high solubility in the alveolar

capillary membrane D. The dispersion of N2O between alveolar gas

and blood is considered as diffusion limited. Which of the above statement(s) is/are

INCORRECT ? 1. Only A 2. A and B 3. Only C 4. C and D

111. भमतरि िमिा पर बाu दाब िनॳ िी सवॳदना िी षति िारझणि िरिा हॴ जबकि सापॳषि: ददा सवॳदना अटट रहिा हॴ। उसी िमिा पर स ानीu तन चॳिि

िॳ ववतनuोग सॳ, दसरी िरफ, िनॳ िी सवॳदना िो बनाuॳ रखिॳ हदuॳ ददा िी सवॳदना िी षति िो रॳररि िरिा हॴ। तनब न ि न म सॳ uॳ रॳषण uजuि हो सििॳ ह:

A. बाu दाब अल प uासी सवॳदि िमिा रॳााओ म आवॳग िी चालििा िो षति पहदचिा हॴ।

B. स ानीu तन चॳिि वह uासी िमिा रॳखाओ म आवॳग िी चालििा िो िम िरिॳ ह।

C. रॳखा रिार A सॳ िनॳ सॳ रॳररि आवॳग वदहि होिॳ ह।

D. ददा सवॳदना िॳ भलए रॳखा रिार C उ िरदाuी हॴ।


1. A ि ा B 2. C ि ा D

3. माम C 4. माम D

111. External pressure given on a mixed nerve

causes loss of touch sensation while pain sensation remains relatively intact. On the other hand application of local anaesthetics on the same nerve, induces loss of pain sensation keeping touch sensation least affected. These observations can be explained by the following statements:

A. External pressure causes loss of conduction of impulses in small diameter sensory nerve fibres

B. Local anaesthetics depress the conduction of impulses in large diameter sensory nerve fibres

C. Touch-induced impulses are carried by fibre type A D. Fibre type C is responsible for pain sensation


1. A and B 2. C and D 3. Only C 4. Only D

112. मानव रuोग-वस िद िी जट पर वाम नॳम षॳम िॳ ववषि िॳ सभा u रभाव तनब न ददuॳ गuॳ ह। सही ि न िो पहचान:

1. वाम नॳम म अधापन परिद दषषण नॳम िा जट षॳम अटट रहिा हॴ।

2. दोन आख िॳ दषषण जट षॳम म अधापन।

3. वाम नॳम जट षॳम िा वामाधा ि ा दषषण नॳम िॳ जट षॳम िा दषषणाधा, दोन म अधापन।

4. दोन आख िॳ जट षॳम िॳ वामाध म अधापन।

112. The probable effects of lesion of left optic tract

on the vision of a human subject are given below. Identify the correct statement.

1. Blindness in the left eye but the visual field of right remains intact.

2. Blindness in the right half of the visual fields of both the eyes.

3. Blindness in the left half of the visual field of left eye and blindness in the right half of the visual field of right eye.

4. Blindness in the left half of the visual field of both the eyes.

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113. ऐरीनल वल िद ट िॳ ोना लोमॳलोसा म स टॴराईडजतनि प िो तनब न तचम दााािा हॴ।

A, B ि ा C रमा: किसिा रतितनतधिव िरिॳ ह?

1. sER, रोगॳस टॳरोन, 11(OH) िोदटासोल

2. समिझणिा, रोगॳस टॳरोन, िोदटािोस टॳरोन

3. समिझणिा, 3-रॴ नॳनोलोन, 11(OH) िोदटासोल

4. sER, रोगॳस टॳरोन, िोदटािोस टॳरोन

113. The following diagram represents steroidogenic pathway in the Zona Glomerulosa of the adrenal cortex:

What do A, B and C represent, respectively? 1. sER, Progesterone, 11(OH) cortisol 2. Mitochondria, Progesterone, Corticosterone 3. Mitochondria, 3-pregnenolone, 11(OH)

cortisol 4. sER, Progesterone, Corticosterone

114. रतिलोमन, ववतनमu तनरोधि मानॳ जािॳ ह स uकि

1. समuद मी रतिलोमन घािि होिॳ ह, एव इससॳ वॳ अगली पीढी म रिट नही होिॳ।

2. रतिलोमन ववमuद मी, अ ााि एि रतिभलवप सामा u गदणसम ि ा उसिा समजाि रतिलोमन

िॳ सा , ववतनमu िो अनदमि नही िरिॳ स uकि वॳ िदावप uदजमि नही हो सििॳ।

3. रतिलोमन िी उपजस ति िॳ िारण uद मन एव ववतनमu घटनाओ म चार गदणसम भाग लॳिॳ ह, ि ा सरचना िो प िन एव uद मि सरचना िॳ भलए िदठन बना दॳिॳ ह।

4. uद मन ि ा ववतनमu रतिलोमन ववमuदजमu म नही घदटि होिॳ, परिद uद मि जजनम ववतनमu उ पाद उपजस ि ह, वॳ घािि होिॳ ह।

114. Inversions are considered as cross-over

suppressors because 1. Homozygous inversions are lethal and thus

they do not appear in next generation 2. Inversion heterozygotes, i.e., one copy having

normal chromosome and its homologue having inversion, does not allow crossing over to occur as they cannot pair at all

3. Due to inversion present, four chromosomes take part in the pairing and crossing over events and make the structure difficult for separation and gamete formation

4. The pairing and crossing overs do occur in inversion heterozygotes but the gametes having cross over products are lethal

115. एि ास u पादप म ऐलील िा एि uदगल बीज आमाप

िो तनधााररि िरिा हॴ। मोटी बीज िॳ भलए उ िरदाuी ‘B’ ऐलील िोटी बीज िॳ भलuॳ उ िरदाuी ‘b’ ऐलील सॳ रभावी हॴ। इस परीषण िॳ भलए कि स uा एि पहचातनि रभावी DNA तचनि (5kb बड) बीज आमाप िो तनuमि िरनॳ वालॳ ऐलील िॳ सा सहलजनि हॴ, एि रuोग किuा गuा। दोन ऐलील और DNA तच ह िॳ भलए ववमuद मी एि पादप सॳ एि िोटी बीज पादि जजसम 5kb बड नही uा सा रसिररि किuा गuा। रसिरण रा ि 100 सिान िा वव लॳण DNA तचनि िी उपजस ति ि ा अनदपजस ति िॳ भलए किuा गuा। पररणाम तनब न िाभलिा म अकिि ह:

लषणरप मोटी बीजवाला पादप

िोटी बीजवाला पादप

DNA तचनि िी उपजस ति uा अनदपजस ति दााािॳ पादप िी स uा

उप- जस ति

अनद- पजस ति



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23

27

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उपरोस ि रॳषण िॳ आधार पर, तनब न तन ि म सॳ िन-सा सही हॴ?

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1. लषणरप सॳ स विम DNA तचनि िादटि होिॳ ह।

2. 5kb बड ऐलील ‘B’िॳ सा सहलजनि हॴ।

3. 5kb बड ऐलील ‘b’िॳ सा सहलजनि हॴ।

4. मोटी बीज सॳ स विमि: DNA तचनि िादटि होिा हॴ, परिद िोटी बीज िी ववाॳिा सॳ सहलजनि हॴ।

115. A pair of alleles govern seed size in a crop

plant. ‘B’ allele responsible for bold seed is dominant over ‘b’ allele controlling small seed. An experiment was carried out to test if an identified dominant DNA marker (5kb band) is linked to alleles controlling seed size. A plant heterozygous for the marker and the alleles was crossed to a small seeded plant lacking the 5kb band. 100 progeny obtained from the cross were analysed for the presence and absence of the DNA marker. The results are tabulated below:

Phenotype Plant with

bold seed Plant with small seed

No. of pro-geny showing presence or absence of DNA marker

Present Absent Present Absent

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23

27

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Based on the above observations which one of

the following conclusions is correct? 1. The DNA marker assorts independently of

the phenotype 2. The 5kb band is linked to the allele ‘B’ 3. The 5kb band is linked to the allele ‘b’ 4. The DNA marker assorts independently with

bold seed but is linked to the small seed trait

116. िीन met– E. coli उ पररविी रभॳद अलग किuॳ गuॳ। उ पररविान िॳ स वभाव िॳ अ uuन हॳिद इन उ पररविी रभॳद िा EMS uा रोलॳववनस उ पररविाजन िॳ सा उपचार किuा गuा, ि ा र uावि िॳ भलए अकिि किuा गuा। पररणाम तनब नवि साराभाि ह:

Mutant strain Mutagen treatment

EMS Proflavin

A - + B + - C - -

( मल उ पररवतिाu िॳ र uावि िो + ि ा िोई र uाविा उपजस ि नही िो– सॳ तनददा ट किuा गuा हॴ)

उपरोस ि ि ा EMS एव रोलॳववन िॳ लषणी उ पररविाजनी रभाव िॳ आधार पर हर रभॳद म मल उ पररविान िा स uा स वभाव ा?

1. A-ववमो पररविान

B- एि षारि िा तनवॳा uा लोपन

C- बहदल षारि िा लोपन

2. A-समो पररविान

B- ववमो पररविान

C- एि षारि िा तनवॳा uा लोपन

3. A- एि षारि िा तनवॳा uा लोपन

B- समो पररविान


4. A- समो पररविान


C- ववमो पररविान

116. Three met– E. coli mutant strains were isolated.

To study the nature of mutation these mutant strains were treated with mutagens EMS or proflavins and scored for revertants. The results obtained are summarized below:


EMS Proflavin

A - + B + - C - -

( + stands for revertants of the original mutants

and – stands for no revertants obtained) Based on the above and the typical mutagenic

effects of EMS and proflavin, what was the nature of the original mutation in each strain?

1. A-Transversion B- Insertion or deletion of a single base C- Deletion of multiple bases 2. A-Transition B- Transversion C- Insertion or deletion of a single base 3. A-Insertion or deletion of a single base B- Transition C- Deletion of multiple bases 4. A- Transition B- Insertion or deletion of multiple bases C- Transversion

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117. तनब न uोजना एि आम सदभा बदद सॳ T4 ववभोजी िॳ rII ववस ल म लोपन (1-4) िा रतितनतध व िरिी हॴ:

व u रिार (rII+) िॳ पदन:सuोजतनu िो रदान िरनॳ िा सामथ uा (+) uा असम ािा (-) िॳ भलए चार बदद उ पररविान (a सॳ d िि) िा, चार लोपन िॳ ववि परीषण किuा जािा हॴ। पररणाम तनब न सषॳवपि ह।

a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -

उपरोस ि िॳ आधार पर बदद उ पररविान िा पवाानदमातनि रम हॴ:

1. b-d-a-c 2. d-b-a-c 3. d-b-c-a 4. c-d-a-b

117. The following scheme represents deletions (1-4) in the rII locus of phage T4 from a common reference point:

Four point mutations (a to d) are tested against

four deletions for their ability (+) or inability (-) to give wild type (rII+) recombinants. The results are summarized below:

a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -

Based on the above the predicted order of the

point mutations is 1. b-d-a-c 2. d-b-a-c 3. d-b-c-a 4. c-d-a-b

118. तनब न वाावली किसी ववाॳि िॳ वाागति रतिमान िो दााािी हॴ।

वाागति िी ढग ि ा इसिी रातuििा कि III पीढी म पदमी वह ववाॳि दाााuॳगी, इनिा अनदमान िीजजuॳ।

1. X-सलजनि अरभावी, रातuििा 1/2 हॴ। 2. X-सलजनि अरभावी, रातuििा 1/4 हॴ।

3. अभलगसमी अरभावी, रातuििा 1/2 हॴ।

4. अभलगसमी अरभावी, रातuििा 1/3हॴ।

118. The following pedigree shows the inheritance pattern of a trait.

From the following select the possible mode of

inheritance and the probability that the daughter in generation III will show the trait.

1. X-linked recessive, probability is 1/2 2. X-linked recessive, probability is 1/4 3. Autosomal recessive, probability is 1/2 4. Autosomal recessive, probability is 1/3

119. िीन अलग Hfr रभॳद िॳ उपuोग सॳ अिरातuि सगम रuोग किuॳ गuॳ। िीन (1 -3) रभॳद वरणीu तचनि िॳ अलग सuोजन रखिॳ ह। तनब न िाभलिा म हर रभॳद िॳ भलए हर तचनि िा रवॳा समu दाााuा गuा हॴ।

Strain Time of entry Hfr #1 met

(5’) thr (17’)

strr

(25’) phe (30’)

pro (45’)

Hfr #2 strr

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)

उपरोस ि आिा िॳ उपuोग सॳ, E. coli गदणसम पर तचनि िॳ सही रम िा पवाानदमान िर

1. met-thr-strr-phe-pro-purr-his 2. purr-pro-his-met-thr-strr-phe 3. strr-purr-his-met-phe-pro-strr

4. his-met-phe-thr-pro-strr-purr

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119. Interrupted mating experiments were performed using three different Hfr strains (1 -3). The three strains have different combinations of selectable markers. The time of entry for markers for each strain is shown in the table below:


(5’) thr (17’)

str r

(25’) phe (30’)

pro (45’)

Hfr #2 str r

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)

Using the above data, predict the correct seque-

nce of markers on the E. coli chromosome. 1. met-thr-str r-phe-pro-purr-his 2. pur r-pro-his-met-thr-str r-phe 3. str r-pur r-his-met-phe-pro-str r

4. his-met-phe-thr-pro-strr-pur r

120. पॳररपॳटस एि ददलचस प जीववि राणी हॴ जजसिॳ बना सतध िॳ पॴर, वस ि, रस िगदहा, वासरणाल, प ठeu नभलिाई दu, पजॳ, जबाा ारीर-भभजि म सिि पॳाी परि ह। इसिो इन दोन िॳ बीच िा सuोजी बध माना जािा हॴ।

1. गोलिभम ि ा ऐनॳभलाा: ारीर-भभजि म सिि पोाी परि, बना सतध िॳ पॴर ि ा वस ि गोलिभम िॳ लषण ह जबकि रस िगदहा, वासरणाल ि ा प ठeu नभलिाई दu ऐनॳभलाा िॳ लषण ह।

2. ऐनॳभलाा ि ा सतधपाद: बना सतध िॳ पॴर, ि ा वस ि ऐनॳभलाा िॳ लषण ह जबकि पजॳ, जबाॳ, रस िगदहा, वासरणाल ि ा प ठeu नभलिाई दu सतधपाद िॳ लषण ह।

3. सतधपाद ि ा मददिवची: बना सतध िॳ पॴर ि ा वस ि मददिवतचu िॳ लषण ह जबकि पजॳ, जबाॳ, वासरणाल ि ा प ठeu नभलिाई दu सतधपाद िॳ लषण ह।

4. गोलिभम ि ा सतधपाद: सिि पॳाी परि, बना सतध िॳ पॴर, ि ा वस ि गोलिभम िॳ लषण ह जबकि पजॳ, जबाॳ, वासरणाल ि ा प ठeu नभलिाई दu सतधपाद िॳ लषण ह।

120. Peripatus is an interesting living animal having

unjointed legs, nephridia, haemocoel, trachea, dorsal tubular heart, claws, jaws, continuous muscle layers in body wall. This is considered as a connecting link between

1. Nematoda and Annelida: continuous muscle layers in body wall, unjointed legs and nephridia being nematode characters while haemocoel, trachea and dorsal tubular heart being annelid characters

2. Annelida and Arthropoda: unjointed legs and nephridia being annelid characters while claws, jaws, haemocoel, trachea and dorsal tubular heart being arthropod characters

3. Arthropoda and Mollusca: unjointed legs and nephridia being mollusca characters while claws, jaws, trachea and dorsal tubular heart being arthropod characters

4. Nematoda and Arthropoda: continuous muscle layers, unjointed legs and nephridia being nematode characters while claws, jaws, trachea and dorsal tubular heart being arthropod characters.

121. तनब न uवस ा मि तचम आविबीजजu म वविीuि वविास िा रतितनतध व िरिा हॴ।

उपरोस ि uोजना िॳ आधार पर A, B, C ि ा D सॳ लॳबभलि एधाओ िा सही रतितनतध व तनब न वविल प म सॳ िन-सा िरिा हॴ?

1. A – अिरापलीu, B – पलीu, C – सवहनी, D – िाग

2. A – पलीu, B – अिरापलीu, C – सवहनी, D – िाग

3. A – िाग, B – अिरापलीu, C – पलीu, D – सवहनी 4. A – िाग, B – पलीu, C – अिरापलीu, D – सवहनी

121. The following schematic diagram represents secondary growth in the angiosperms.

Based on the above scheme, which of the

following options represents the correct identity of cambia labelled as A, B, C and D.

1. A – Inter-fascicular, B – Fascicular, C – Vascular, D – Cork

2. A – Fascicular, B – Inter-fascicular, C – Vascular, D – Cork

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3. A – Cork, B – Inter-fascicular, C – Fascicular, D – Vascular

4. A – Cork, B – Fascicular, C – Inter- fascicular, D – Vascular

122. तनब न िाभलिा रमदख िविी समह ि ा उनिॳ

लषण िी सची रदान िरिी हॴ:

कवकी समह लषण A ऐसिोमाइभसटी (i) िवि ििद पटहीन

सिोभािी बीजाणदधानी धर वारा अलतगि जनन

B िाईदरा (ii) िवि ििद पटहीन, सिोभािी; अलतगि चल बीजाणद वारा अलतगि जनन

C लोमॳरामाइभसटी (iii) िवि ििद पटहीन, सिोभािी; िोई लतगि बीजाणद नही

D ाईगोमाइभसटी (iv) िवि ििद पटuदस ि uा एििोभािाई; िोतनडडuा वारा अलतगि जनन

तनब न वविल प म सॳ िन-सा िविी समह ि ा उनिॳ लषण िॳ उपuदस ि मॳलान िा रतितनतध व िरिॳ ह?

1. A – (ii), B – (iii), C – (i), D – (iv) 2. A – (iv), B – (ii), C – (iii), D – (i) 3. A – (i), B – (iv), C – (iii), D – (ii) 4. A – (ii), B – (iv), C – (iii), D – (i)

122. The table below lists the major fungal groups and their characteristics:

Fungal Groups Characteristics A Ascomycota (i) Hyphae aseptate,

coenocytic; asexual reproduction by sporangiophores

B Chytrids (ii) Hyphae aseptate, coenocytic; asexual reproduction by zoospores

C Glomeromycetes (iii) Hyphae aseptate, coenocytic; no sexual spores

D Zygomycetes (iv) Hyphae septate or unicellular; asexual reproduction by conidia

Which one of the following options represents the appropriate match between the fungal group and their characteristics?


123. एि जॴववॴञातनि होिर आप िीन टॴस सा A, B ि ा C िा वगीिरण िरना चाहिॳ ह। आपिॳ पास िीन ववाॳि p, q ि ा r िॳ बारॳ म सचना हॴ। ववाॳि जो पॴिि हॴ, ‘0’ तगना जािा हॴ ि ा ववाॳि जो uदिप न हॴ, ‘1’ तगना जािा हॴ। िीन टॴस स म पाuॳ गuॳ ववाॳि िा बटन तनब नवि हॴ:

A B C

p 1 1 0 q 1 1 0 r 0 1 1

उपरोस ि िाभलिा िॳ आधार पर, तनब न ााखापट खीचॳ गuॳ।

ववाॳि बटन ि ा भमि uu भसिाि िॳ आधार पर, सही वविल प िो चदन।

1. ‘a’ ि ा ‘b’ दोन ााखापट सभव ह।

2. माम ‘b’ ााखापट सभव ह।

3. माम ‘c’ ााखापट सभव ह।

4. माम ‘a’ ााखापट सभव ह।

123. As a biologist, you want to classify three taxa,

A, B and C. You have the information on three traits, p, q and r. The trait that is ancestral is counted ‘0’ and the trait that is derived is counted as ‘1’. The distribution of traits found in three taxa is given below

A B C p 1 1 0 q 1 1 0 r 0 1 1

Based on the above table, the following

cladograms were drawn:

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Based on trait distribution and the principle of

parsimony, select the correct option. 1. Both ‘a’ and ‘b’ cladograms are possible 2. Only ‘b’ cladogram is possible 3. Only ‘c’ cladogram is possible 4. Only ‘a’ cladogram is possible

124. िद ि ववितिजन ि ा मानव, राणी ि ा पादप िॳ रोग तनब न ददuॳ गuॳ ह।

A बोडटॳल ला पॳटद ाजससस (i) मानव िा लाइम

रोग

B दटल लॳदटuा इडडिा (ii) चावल म अनाज सान

C बोरभलuा बदगाडोफा री (iii) गॳह िा िनााल बट रोग

D ऐना लाामा माजजानाली

(iv) मानव म िद िद रखासी

E बदखोल डॳररuा लमी (v) गाu-बॴल म तधरलuनी रस िषीणिा

ववितिजन ि ा रॳररि रोग िा सही मॳलान तनब न म सॳ िन-सा हॴ?

1. A – (iv), B – (iii), C – (i), D – (v), E – (ii) 2. A – (iv), B – (v), C – (i), D – (ii), E – (iii) 3. A – (iii), B – (iv), C – (v), D – (i), E – (ii) 4. A – (ii), B – (v), C – (i), D – (iii), E – (iv)

124. Given below are some pathogens and diseases of humans, animals and plants.

A Bordetella

pertussis (i) Lyme disease of

humans B Tilletia indica (ii) Grain rot in rice C Borrelia

burgdorferi (iii) Karnal bunt of

wheat D Anaplasma

marginale (iv) Whooping

cough in humans

E Burkholderia glumae

(v) Hemolytic anemia in cattle

Which one of the following is the correct match

between the pathogen and disease caused? 1. A – (iv), B – (iii), C – (i), D – (v), E – (ii) 2. A – (iv), B – (v), C – (i), D – (ii), E – (iii) 3. A – (iii), B – (iv), C – (v), D – (i), E – (ii) 4. A – (ii), B – (v), C – (i), D – (iii), E – (iv)

125. जीवन िॳ िीन षॳम पर पानॳवालॳ जीव िॳ बारॳ म तनब न ि न ददuॳ गuॳ ह। गलत ि न िो पहचान:

1. जीवाणद ि ा सदिरि सॳ असा, िद ि आ u झिल ली भलवपा लबी ाखला हाईरोिॉबान अिववाजटि िरिॳ ह जो ई र सल नन वारा जलसॳरॉल अणदओ िॳ सा बतधि हॴ।

2. पॴजटडो लाईिनस आ u िी िोभािा भभजि म अनदपजस ि ह।

3. रोदटuोजीवाणद, सल फर उपuोग िरिॳ, जीवाणदस लोरोक फल रखिॳ रिाास वपोवu िी िई रजातिu िो ााभमल िरिॳ ह।

4. माईिो लाामा, िम GC मामा िा एि समह, राम-धन जीवाणद जजनिी िोभािा-भभजि नही हॴ, उसी िद टद ब सॳ सबतधि ह जॴसॳ कि राम-धन माइिोजीवाणद।

125. Given below are statements pertaining to

organisms belonging to three domains of life. Identify the INCORRECT statement.

1. Unlike Bacteria and Eukarya, some Archaeal

membrane lipids contain long chain hydrocarbons connected to glycerol molecules by ether linkage.

2. Peptidoglycans are absent in the cell wall of Archaea

3. Proteobacteria include many species of bacteriochlorophyll-containing, sulphur using photoautotrophs.

4. Mycoplasma, a group of low GC content, gram positive bacteria that lack cell wall,

belong to the same family as the gram positive Mycobacteriaceae

126. आप uह रॳषण िरिॳ ह कि नाितचमटी िी दो

रजातिuा, रजाति 1 ि ा रजाति 2, अिरा वारीu ाॴल िी रमा: ऊपरी ि ा तनचली परि म तनवास िरिी ह। जब आपसॳ रजाति 2 तनचली परि सॳ तनिाल दी जािी हॴ, िभी रजाति 1 ऊपरी ि ा तनचली, दोन परि म तनवास िर सििी हॴ। इन रॳषण सॳ आपिा तन िा तनब न ददuॳ गuॳ वविल प म सॳ स uा होगा?

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1. रजाति 1 िी रा ि िाखा हॴ अिरा वारीu ाॴल िी उपरी परि।

2. रजाति 1 िी मलभि िाखा हॴ अिरा वारीu ाॴल िी ऊपरी परि।

3. रजाति 1 ि ा रजाति 2 सहोपिाररिा दााािी ह।

4. रजाति 1, रजाति 2 िॳ साद रतिस पिाा िरिॳ उसॳ हरा सििी हॴ।

126. You observed that two species of barnacles,

species 1 and species 2, occupy upper and lower strata of intertidal rocks, respectively. Only when species 2 was removed by you from the lower strata, species 1 could occupy both the upper and lower strata. From the choices given below, what would be your inference from these observations?

1. Upper strata of the intertidal rock is the realized niche of species 1

2. Upper strata of the intertidal rock is the fundamental niche of species 1

3. Species 1 and species 2 exhibit mutualism 4. Species 1 can compete out species 2

127. एि राितिि िम म, एि बहदसिानी रजाति, अल प uा बना िोई पॴिि दॳख-भाल िी, तनब न रिार िी उ िरजीवविा वर म सॳ, सामा uि: किसिो दाााuॳगी?

127. In a natural system, a species producing large numbers of offsprings, with little or no parental care, generally exhibits which one of the following kind of survivorship curves?

128. ाीिो ण घासभभमu िॳ सही स ानीu नाम िो अपनॳ भगोलीu पररसर िॳ सा सदमॳभलि िर:

भगोलीu पररसर घासभभम िा स ानीu नाम

(i) एभाuा A पापास

(ii) उ िर अमॳररिा B रॳuरीस

(iii) दषषण अमॳररिा C स टॳ पीस

(iv) दषषण अरीिा D वॳल ी

1. (i) – C, (ii) – B, (iii) – D, (iv) – A 2. (i) – C, (ii) – B, (iii) – A, (iv) – D 3. (i) – D, (ii) – B, (iii) – A, (iv) – C 4. (i) – B, (ii) – C, (iii) – A, (iv) – D

128. Match the correct local names of temperate grasslands with their geographical range.

Geographical range Local name of

the grassland (i) Asia A Pampas (ii) North America B Prairies (iii) South America C Steppes (iv) South Africa D Veldt


129. किसी रजाति िॳ भलए पररिजलपि जीवन िाभलिा तनब नवि हॴ:

आuद वगा (x)

जीववि िी स uा

(nx)

मरनॳ वाल िी स uा

(dx)

आuद-ववभा ट उ िर-जीवविा

(lx)

आuद-ववभा ट जनन षमिा (mx)

0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0

तनब न म सॳ िन-सा सही ादि रजनन गति हॴ (Ro)? 1. 0.0 2. 0.3 3. 0.7 4. 1.5

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129. Following is a hypothetical life table for a species.

Age class (x)

Number alive (nx)

Number dying (dx)

Age specific

survivor-ship (lx)

Age specific fertility

(mx)

0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0

Which one of the following is the correct net

reproductive rate (Ro)? 1. 0.0 2. 0.3 3. 0.7 4. 1.5

130. किसी बदद-रोि सॳ रद ि िो रा ि िरिी एि जल सररिा िॳ ववलीन ऑस सीजन (DO) ि ा जॴव ऑस सीजन माग (BOD) म रवजिu िॳ भलए तनब न ि न म सॳ िन-सा सही हॴ?

1. किसी पतिि षॳम म, DO ि ा BOD दोन िॳ स िर स ि ध रहिॳ ह।

2. किसी पदन:राजि षॳम म DO ि ा BOD दोन िॳ स िर िॳजी सॳ बढिॳ ह।

3. किसी अपघटन षॳम म DO स िर िॳजी सॳ तगरिा हॴ, जबकि BOD स िर लगभग स ाuी रहिा हॴ।

4. किसी पतिि षॳम म DO स िर घटिा हॴ ि ा BOD स िर वविि होिा ह, जबकि किसी पदन:राजि षॳम म DO वविि होिा हॴ ि ा BOD

घटिा हॴ।

130. Which one of the following statements is true for the trends of Dissolved Oxygen (DO) and Biological Oxygen Demand (BOD) in a water stream receiving pollutants from a point source?

1. In septic zone, both DO and BOD levels remain stationary

2. In recovery zone, both DO and BOD levels increase rapidly

3. In decomposition zone, DO level drops rapidly, whereas BOD level remains more or less stable

4. In septic zone, DO level decreases and BOD level increases whereas in recovery zone DO increases and BOD decreases

131. रजाति-रचदरिा (X-अष) ि ा समददाu सॳवा (Y-अष) िॳ बीच सभा u सबध िी uा uा हॳिद रस िाववि ववभभ न पररिल पनाओ िॳ आलॳखीu रतितनतध व तनब नवि ह।

पररिल पना ि ा आलॳखीu रतितनतध व िॳ बीच सही मॳलान तनब न वविल प म सॳ िन-सा हॴ?

1. (a) अतिररस ििा, (b) िद जीभाला, (c) िीलि, (d)

ववलषणिाuी 2. (a) ववलषणिाuी, (b) िीलि, (c) िद जीभाला, (d)

अतिररस ििा 3. (a) िीलि, (b) अतिररस ििा, (c) ववलषणिाuी, (d)

िद जीभाला 4. (a) िीलि, (b) िद जीभाला, (c) अतिररि ििा, (d)

ववलषणिाuी

131. Following are the graphical representations of various hypotheses proposed for explaining the possible relationships between species richness (X-axis) and community services (Y-axis).

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Which of the following options is the correct match between the graphical representations and the hypotheses?

1. (a) Redundancy, (b) Keystone, (c) Rivet, (d)

Idiosyncratic 2. (a) Idiosyncratic, (b) Rivet, (c) Keystone, (d)

Redundancy 3. (a) Rivet, (b) Redundancy, (c) Idiosyncratic,

(d) Keystone 4. (a) Rivet, (b) Keystone, (c) Redundancy, (d)

Idiosyncratic

132. तनब न तचम तनब न ववभभ न समu बददओ पर जॴव लu िा रतितनतध व िरिा हॴ: SR = सuोदu; N =

म uान; SS = सuाास ि; MN = अधारामी

ऊपर ददए गए तचम म िनसा समuबि जॴव

लu रतितनतध व िरिा/िरिॳ हॴ/ह?

1. तचम B 2. तचम A ि ा C

3. तचम C ि ा D 4. तचम D

132. Following are the plots representing biological

rhythms at different time points depicted as: SR = Sunrise; N = Noon; SS = Sunset; MN = Midnight

Which of the plot(s) represent the ultradian biological rhythm(s)?

1. Plot B 2. Plots A and C 3. Plots C and D 4. Plot D

133. अववालद तििभलu िी एि आबादी िद ि अतिववालद तििभलu िॳ समप वणा-रतिमान रखिी ह। मान कि अववालद तििभलu िी स uा ववालद तििभलu िी स uा िी अपॳषा िही अतधि ह। इसिॳ ददuॳ जानॳ पर, किसी परभषी िी उपजस ति म ववालद तििभलu िॳ आबादी िी स वस िा पर इस अनदहरण िा स uा सघाि होगा?

1. uह स वस िा िो िम िरॳगा, अ ााि निल िरनॳ वालॳ िी स वस िा ऋणि: बारबाररिा-तनभार हॴ।

2. uह स वस िा िो वविि िरॳगा, अ ााि निल िरनॳ वालॳ िी स वस िा धनि: बारबाररिा-तनभार हॴ।

3. uह स वस िा पर िोई असर नही िरॳगा, अ ााि निल िरनॳ वालॳ िी स वस िा बारबाररिा सॳ स विम हॴ।

4. uह स वस िा िो वविि िरॳगा, अ ााि निल िरनॳ वालॳ िी स वस िा ऋणि: बारबाररिा-तनभार हॴ।

133. A population of non-poisonous butterflies have

the same colour pattern as some highly poisonous butterflies. Assume that the population of non-poisonous butterflies is higher than the population of poisonous butterflies. Given this, what will be the impact of this mimicry on the fitness of the population of the poisonous butterflies in the presence of the predator?

1. It will lower the fitness, that is, fitness of the mimic is negatively frequency-dependent

2. It will increase the fitness, that is, fitness of the mimic is positively frequency-dependent

3. It will not affect the fitness, that is, fitness of the mimic is frequency independent

4. It will increase the fitness, that is, fitness of the mimic is negatively frequency-dependent

134. भवॴञातनि समu आमाप िी समuावतध िॳ दरान

आिति-मलि पररविान िा आलॳखीu रतितनतध व तनब न ददuा गuा हॴ, जहा आबादी A वाागि आिति-मलि पररविान िॳ सरहण वारा एि सदस प ट रजाति B िो ज म दॳिी हॴ। रजाति B एि सदस प ट रजाति B2 म ववभाजजि होिी हॴ।

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ााखजनन वारा रजा िीिरण िॳ रतिमान िो उपरोस ि वाागतिu म सॳ िन-सॳ िरिी ह?

1. वाागति - 1

2. दोन, वाागतिuा 1 ि ा 2

3. वाा गति 2

4. दोन, वाागतिu 1 ि ा 2 म िोई भी नही

134. Given below is a graphical representation of

changes in morphological features over a period of geological time scale, where population A accumulates heritable morphological changes and give rise to a distinct species B. Population B splits into a distinct species B2

Which of the above lineages represent the

pattern of speciation by cladogenesis? 1. Lineage 1 2. Both the lineages 1 and 2 3. Lineage 2 4. Neither of the lineages 1 and 2

135. मानव म लाल रोम एि अरभावी ववाॳि हॴ। हाडी-वॳ बगा साब uावस ा म रहिी एि uाजछििि: सगम िरिी आबादी म, लगभग 9% uजसि लाल रोम वालॳ ह। ववमuद मज िी बारबाररिा स uा हॴ?

1. 81% 2. 49% 3. 42% 4. 18%

135. Red hair is a recessive trait in humans. In a randomly mating population in Hardy-Weinberg equilibrium, approximately 9% of individuals are red-haired. What is the frequency of heterozygotes?

1. 81% 2. 49% 3. 42% 4. 18%

136. 6129 uजसिu िी एि आबादी म M-N तधर रिार िी बारबाररिा तनब नवि हॴ:

धिर रकार जीन रप यतितय की स या M LMLM 1787

MN LMLN 3039 N LNLN 1303

LN ऐलील िी इस आबादी म बारबाररिा हॴ: 1. 0.4605 2. 0.2121 3. 0.5395 4. 0.2911

136. The frequency of M-N blood types in a population of 6129 individuals is as follows:

Blood type Genotype Number of

individuals M LMLM 1787


The frequency of LN allele in this population is 1. 0.4605 2. 0.2121 3. 0.5395 4. 0.2911

137. मईफॳ र जीन (पररिाल पतनि) म अनदलॳख िारि िी एि अतििद टद ब सजबमभलि हॴ। स ितनu म वॳ 4 गदछ ि म पाuॳ जािॳ ह; िीट म 2 गदछ ि म ि ा िीट िॳ एि पवाज म एिल गदछ ि म। uॳ आिाॳ तनब न सभी uा uाओ िॳ सा अववरोधी हॴ, ससवाय इसक:

1. पवाज जीव ि ा िाॳकिu िॳ बीच दो उ िरो िर सजीन अनदभलवपिरण घटनाu घटी।

2. िाॳकिu िॳ अपसरण िॳ पवा र म अनदभलवपिरण िॳ घदटि होनॳ िी सभावना हॴ।

3. माम बदहरॳि पदनuोजन नॳ ऐसॳ गदछ िॳ िो उ पाददि किuा।

4. सपणा सजीन अनदभलवपिरण ऐसॳ रॳषण म पररणभमि हो सििॳ ह।

137. Mayfair genes (hypothetical) consist of a super

family of transcription factors. They are found in 4 clusters in mammals; in 2 clusters in insects; and in a single cluster in an ancestor to insects. These data are consistent with all of the following explanations EXCEPT:

1. Two successive genome duplication events occurred between ancestral organism

and vertebrates 2. The first duplication may have taken place

before divergence of vertebrates

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3. Exon shuffling exclusively produced such cluster

4. Whole genome duplications could lead to such observations

138. किसी झिल ली म अणदओ िॳ ववसरण िॳ आिलन िॳ

भलए एि ववतध हॴ रिाा-ववरजन िॳ उपराि रतिदीजि पदन:राजि (FRAP) हॴ। ऐसॳ रति दीजिि: लॳबभलि अणद

i. हरॳ रतिदी िि रोटीन (GFP) सॳ तचजनि एि राही

ii. GFP सॳ तचजनि एि राही जो िोभािापजर िॳ सा अ uो uकरuा िरिा हॴ

iii. एि तचजनि वसा

iv. झिल ली िी सिह िॳ सा बतधि होनॳवाला एि तचजनि रोटीन,

िॳ ववसरण गदणाि िॳ आिलन िॳ भलए, रिाा-

ववरजजि किuॳ गuॳ ि ा पदन:राजि (a-d) पाuी गuी।

तनब न आिाॳ पाuॳ गuॳ:

सuोजन म सॳ िन-सा सही हॴ? 1. a = i; b = ii 2. b = iii; a = iv 3. c = iii; d = iv 4. d = ii; b = i

138. Fluorescence recovery after photobleaching

(FRAP) is a method to estimate the diffusion of molecules in a membrane. Fluorescently labelled molecules such as

i. a receptor tagged with green fluorescent protein (GFP)

ii. a receptor labelled with GFP which interacts with cytoskeleton

iii. a labelled lipid iv. a labelled protein that binds to the

membrane surface are photobleached and the recovery profiles (a-d) were obtained to estimate their diffusion

coefficients.

The following data were obtained:

Which one of the combinations is correct? 1. a = i; b = ii 2. b = iii; a = iv 3. c = iii; d = iv 4. d = ii; b = i

139. पारजीनी पादप िॳ जनन िॳ भलए ऐरोबॴस टीररuम

Ti लाज मा सवाहि िाम म भलuॳ जािॳ ह। पादप िॳ अदर T-DNA िॳ स ानािरण िॳ भलए मह वपणा vir जीन िटभलझखि रोटीन िॳ तनब न उदाहरण ह:

A. Vir E, एि एिल-र जदि DNA आबधन रोटीन

B. Vir D2, जो T-र जदि िा जनन िरिा हॴ।

C. Vir A, जो पादप-फीनोभलि uतगि िा बोध िरािा हॴ।

D. Vir F, जो रादटuोसोम म ववनाा िॳ भलए T-

सिद ल रोटीन िा मागााान िरिा हॴ।

रोटीन िॳ तनब न सuोजन म सॳ िन-सा एि, पादप िोभािाओ िॳ अदर िाuा िरिा हॴ?

1. माम A ि ा C 2. A, B ि ा C

3. माम B ि ा C 4. A, B ि ा D

139. Agrobacterium Ti plasmid vectors are used to

generate transgenic plants. The following are examples of vir gene-encoded proteins that are important for the transfer of T-DNA into plants:

A. Vir E, a single-stranded DNA binding protein

B. Vir D2 that generates T-strands C. Vir A that senses plant phenolic compounds D. Vir F which directs T-complex proteins for

destruction in proteasomes Which one of the following combinations of

proteins functions inside the plant cells? 1. Only A and C 2. A, B and C 3. Only B and C 4. A, B and D

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140. किसी रोटीन म होिॳ सरचनाuी पररविान िा एि ाोधििाा दर टोफान रतिदीजि ि ा व िीu वववणािा (CD) िॳ अनदिरण वारा अनदसधान िरिा हॴ। किसी उपचार िॳ बना (a), 0.5 मोलार uररuा िी उपजस ति म (b), दर टोफान िा एि ामनििाा, ऐकरलामाईा सॳ भमलानॳ पर (c) ि ा ऊ मन पर (d),

एि ादि रोटीन िी रतिदीजि एव CD वणामालाu रा ि िी गuी। आिाॳ तनब न दाााuॳ गuॳ ह।


1. रतिददजि िी अपॳषा सरचनाuी पररविान पर CD िही अतधि सवॳदनाील हॴ।

2. CD िी अपॳषा सरचनाuी पररविान पर रतिदीजि िही अतधि सवॳदनाील हॴ।

3. सरचनाई पररविान पर दोन ववतधuा समानि: रभावनीu ह।

4. रोटीन िी वविीuि सरचना िो ऐकरलामाईा बदल दॳिा हॴ।

140. A researcher is investigating structural changes

in a protein by following tryptophan fluorescence and by circular dichroism (CD). Fluorescence and CD spectra of a pure protein were obtained in the absence of any treatment (a), in the presence of 0.5 M Urea (b), upon adding acrylamide, a quencher of tryptophan (c) and upon heating (d). The data are shown below:

Which one of the following statements is correct?

1. CD is more sensitive to structural changes than fluorescence

2. Fluorescence is more sensitive to structural changes than CD

3. Both methods are equally responsive to structural changes

4. Acrylamide alters the secondary structure of the protein

141. पॉभल uजसलuोटाइा ाखलाओ िॳ अफॉस फोररलीिि

5 - भारा िॳ फॉस फोररलीिरण वारा DNA uा RNA

िॳ रॳडडuोतचनन िॳ भलए राu: पाभल uजसलuोटाइा िाइनॳस (PNK) िाम आिा हॴ। PNK िॳ बारॳ म किuॳ गuॳ तनब न ि न म सॳ िन-सा सही नह हॴ?

1. ATP सॳ पॉभल uजसलuोटाइा ाखलाओ (DNA uा RNA) िॳ 5 -भारॳ िि α-फॉस फॳ ट िॳ स ानािरण िो PNK उ रॳररि िरिा हॴ।

2. PNK िी 3 -फॉस फटॳस गतिववतध हॴ।

3. अब मोतनuम अuन िॳ अल प मामा सॳ PNK

सदभमि होिा हॴ।

4. PNK एि T4 बॴस टीररuोफॳ ज-िटभलझखि ए जा ईम हॴ।

141. Polynucleotide kinase (PNK) is frequently used for radiolabeling DNA or RNA by phosphorylating 5 - end of non-phosphorylated polynucleotide chains. Which of the following statement about PNK is NOT true?

1. PNK catalyzes the transfer of α-phosphate from ATP to 5 -end of polynucleotide chains (DNA or RNA).

2. PNK has 3 -phosphatase activity 3. PNK is inhibited by small amount of

ammonium ions 4. PNK is a T4 bacteriophage-encoded enzyme

142. T7 RNA पॉभलमरॳ उ नाuि ि ा lac सिारि िॳ अिगाि रोटीन X िॳ भलए िटलॳखन िरिॳ एि जीन िो एि अभभ uजसि सवाहि म स लोतनि किuा गuा। 37C पर 6 घटॳ िॳ भलए 1 mM IPTG िॳ भमलानॳ सॳ िोभािाu रॳररि िी गuी। िोभािाओ िॳ लuन िरिॳ अववलॳu वपड ि ा िोभािा-मदस ि अतध लावी म अपिरीिरण वारा रभाजजि किuॳ गuॳ। अववलॳu वपड म रोटीन X उपजस ि हॴ। (िोभािा-मदस ि अतध लावी) ववलॳu रभाग म रोटीन X िो अभभ uस ि िरनॳ िॳ रu न म नीचॳ ददए गए िन-सी uदिनीति िा आप उपuोग िरगॳ?

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1. 1 mM IPTG सॳ रॳरण िी िालवतध िो बढािर

2. 1 mM IPTG सॳ रॳरण िॳ उपराि अल पिर िाप म िोभािाओ िॳ वविास सॳ

3. IPTG िी सारिा िो बढािर

4. 1 mM IPTG सॳ रॳरण िॳ उपराि उछ चिर िाप म िोभािाओ िॳ वविास सॳ

142. A gene encoding for protein X was cloned in an

expression vector under the T7 RNA polymerase promoter and lac operator. Cells were induced by the addition of 1 mM IPTG at 37C for 6 h. Cells were lysed and fractionated into insoluble bodies and cell-free supernatant by centrifugation. Protein X is present in the insoluble bodies. Which one of the following strategies would you use to express protein X in the soluble fraction (cell-free supernatant)?

1. Increase the duration of induction with 1mM IPTG 2. Grow cells at lower temperature after

induction with 1 mM IPTG 3. Increase the concentration of IPTG 4. Grow cells at higher temperature after

induction with 1 mM IPTG

143. पादप म उपापचuी प िी अभभuामिी, पारजीनी ििनीिी िॳ उपuोग सॳ, उपuदस ि अ u ी जीन िॳ सजनवव टन ि ा अतिअभभजuजसि वारा उपाजजाि िी जा सििी हॴ। पादप म एि जॴवरासाuतनि प िा तनब न तचम रतितनतध व िरिा हॴ जहा ए जाईमाई अभभकरuाओ िॳ एि अनदरम वारा एि पवागामी अणद ‘A’ िो उ पाद ‘T’ ि ा ‘X’ म बदला जािा हॴ। इस प म ए ाईम 1-5 सजबमभलि ह। एि रबल सघटि उ नाuि िॳ अनदलॳखी तनuमण िॳ अिगाि, ए जाइाम ‘5’ िॳ भलए एि अतिररस ि रतिभलवप िॳ सजनवव टन वारा वॴञातनि नॳ ‘X’

िॳ स िर िो बढानॳ िा रu न किuा। ि ावप, वविभसि पारजीनी पादप नॳ ‘X’ िॳ स िर म एि अनदपा िीu ववि नही दाााuी।

उपरोस ि पररणाम िी uा uा िॳ भलए तनब न ि न रस िाववि किuॳ गuॳ।

A. ए ाईम ‘3’ िी िदलना म D िॳ भलए ए ाईम

‘4’ अतधि आिाण रखिा हॴ।

B. uतगि X वारा ए ाईम ‘5’ िा पदनतनावॳा िा सदमन

C. ए ाईम ‘5’ िॳ भलए करuाधार िा पररसीमन

पारजीनी पादप म X िी मामा म अनदपािी ववि िॳ न पाuॳ जानॳ िॳ सभाववि िारण िा उपरोस ि ि न म सॳ िन-सॳ रतितनतध व िर सििॳ ह?

1. माम C 2. माम A ि ा B

3. माम A 4. A, B ि ा C

143. Engineering of metabolic pathways in plants

can be achieved by introduction and over expression of appropriate candidate gene(s) using transgenic technology. The figure given below represents a biochemical pathway in plants where a precursor molecule ‘A’ is converted into products ‘T’ and ‘X’ through a series of enzymatic reactions. Enzymes 1-5 are involved in this pathway. Scientists attempted to increase the level of ‘X’ by introducing an additional copy of the gene for enzyme ‘5’ under transcriptional control of a strong constitutive promoter. However, the developed transgenic plants did not display a proportionate increase in the level of ‘X’.

The following statements were proposed for explaining the above results:

A. Enzyme ‘4’ has greater affinity for D than enzyme ‘3’

B. Feedback inhibition of enzyme ‘5’ by compound X

C. Substrate limitation for enzyme ‘5’ Which of the above statements could represent

probable reasons for NOT obtaining a proportionate increase in the amount of X in the transgenic plants?

1. Only C 2. Only A and B 3. Only A 4. A, B and C

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144. िविी रतिरोध िॳ भलए पारजीन ‘A’ रखनॳवालॳ एि एिल रतिभलवप समuद मज पारजीनी पादप िो बाद म लवण-रतिबल दॳनॳ िॳ भलए एि दसरॳ जीन ‘B’ िॳ सा पदन: पािररि किuा गuा। दोन पािरण रuोग म िाम म भलuॳ जानॳ वालॳ वरण तचनि जीन अलग ॳ। पदन: पािरण रuोग सॳ पाuॳ गuॳ पारजीनी पादप िो लवण-रतिबल रतिरोध िॳ भलए परीषषि किuा गuा ि ा सदना-सिरण वारा एिल रतिभलवप घटनाu पहचानी गuी। uॳ एिल रभलभलवप घटनाu स वतनॳतचि ी। सभी पारजीनी पादप म दो T-DNAs (A ि ा B पारजीन िो अिववाजटि) िॳ असलजनि स ान पर समािलन होनॳ पर T1 सिान म लषणरपी अनदपाि हगॳ:

1. 3 (िविी रतिरोधी+ लवण-रतिबल रतिरोधी): 1

(िविी रतिरोधी) 2. 1 (िविी रतिरोधी): 2 (िविी रतिरोधी + लवण-

रतिबल रतिरोधी): 1 (लवण-रतिबल रतिरोधी) 3. 3 (लवण-रतिबल रतिरोधी): 1 (िविी रतिरोधी) 4. 1 (िविी रतिरोधी): 1 (लवण-रतिबल रतिरोधी):1

(िविी रतिरोधी + लवण-रतिबल रतिरोधी)

144. A single copy homozygous transgenic plant

containing the transgene ‘A’ for fungal resistance was subsequently re-transformed with another gene ‘B’ for conferring resistance to salt-stress. The selection marker genes used for both the transformation experiments were different. Transgenic plants obtained following the re-transformation experiment were screened for salt-stress resistance and single copy events were identified by Southern hybridization. These single copy events were self-pollinated. In the event of the two T-DNAs (containing the A and B transgenes) getting integrated in unlinked locations in all the transgenic plants, the phenotypic ratios among the T1 progeny would be:

1. 3 (Fungal resistant + Salt-stress resistant): 1 (Fungal resistant)

2. 1 (Fungal resistant): 2 (Fungal resistant + Salt-stress resistant): 1 (Salt-stress resistant)

3. 3 (Salt-stress resistant): 1 (Fungal resistant) 4. 1 (Fungal resistant): 1 (Salt-stress

resistant):1 (Fungal resistant + Salt stress resistant)

145. एि GST सलuन रोटीन बनानॳ िॳ भलए आप 2kb

लबाई िॳ एि जीन िो एि 3kb िॳ सवाहि िॳ अदर तनवॳा िरिॳ ह। जीन EcoRI स ल पर तनवॳभाि होिा हॴ ि ा तनवॳा म र म िोाान सॳ 500bp

अनदरवाह एि HindIII स ल हॴ। HindIII plus

BamHI (H+B) ि ा HindIII plus PstI (H+P) िॳ उपuोग सॳ लाज मड िॳ रतिबधन-पाचन वारा आप सही वव uास िॳ स लोन िॳ भलए परीषण िर रहॳ ह। सवाहि िॳ उतचि राि िा मानतचम तनब न दाााuा गuा हॴ।

चार स विम स लोन (A, B, C uा D) सॳ अलतगि लाज मड िॳ रतिबधन-पाचन िॳ उपराि रा ि रतिमान तनब नवि ह:

ऊपर दाााuॳ गuॳ लाज मा म िन-सा, सही वव uास वालॳ स लोन िा रतितनतध व िरिा हॴ?

1. A 2. B 3. C 4. D

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145. You are inserting a gene of 2kb length into a vector of 3kb to make a GST fusion protein. The gene is being inserted at the EcoRI site and the insert has a HindIII site 500bp downstream of the first codon. You are screening for the clone with the correct orientation by restriction digestion of the plasmid using HindIII plus BamHI (H+B) and HindIII plus PstI (H+P). The map of the relevant region of the vector is shown below:

Given below is the pattern following restriction digestion of plasmid isolated from four independent clones (A, B, C or D).

Which of the plasmids shown above represents

the clone in the correct orientation? 1. A 2. B 3. C 4. D

FOR ROUGH WORK

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vuqns’k


2. vksñ,eñvkjñ mRrj i=d vyx Lks fn;k x;k gS A viuk jksy uEcj vkSj dsUnz dk uke fy[kus Lks igys ;g tkap yhft, fd iqfLrdk esa i`”B iwjs vkSj lgh gSa rFkk dgha Lks dVs&QVs ugha gSa A ;fn ,slk gS rks vki bfUothysVj Lks mlh dksM dh iqfLrdk cnyus dk fuosnu dj ldrs gSa A blh rjg Lks vksñ,eñvkjñ mRrj i=d dks Hkh tkap ysa A bl iqfLrdk esa jQ dke djus ds fy, vfrfjDr iUus layXu gSa A







OMR mRrj i=d lkSaius ds i’pkr vki bldh dkWcZuySl izfrfyfi ys tk ldrs gSaA 11. fgUnh ek/;[email protected] ds iz’u esa folaxfr gksus@ik;s tkus ij vaxzsth laLdj.k izekf.kd gksxk A


Øekad




jksy uacj :…………………………..

uke :...........................................

2016 (II)


3 B fo”k; dksM iqfLrdk dksM

H

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FOR ROUGH WORK

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Hkkx \PART 'A' 1. लापिा रतिमान िो ञाि िीजजuॳ?



व आuिन म 10% िी ववि होिी हॴ। बीज िा घनि व कििनॳ गदणाि सॳ बढॳगा?







1. 2. 3. 4. 4. किसी एि रजाति िॳ दो तिलचट ह, जजनिी










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नीचॳ ददuॳ गuॳ पाई-तचम म सॳ िन-सा इस जानिारी िो सही दााािा हॴ?




6. ि ा Q िॳ मापन सबतधि uाजछिि अादविuा रमा: 10% ि ा 2% ह। P/Q म रतिाि uाजछिि अादवि कििनी हॴ?




िो uवजस ि किuा जा सििा हॴ? 1. 120 2. 720 3. 360 4. 240 7. In how many distinguishable ways can the

letters of the word CHANCE be arranged? 1. 120 2. 720 3. 360 4. 240

8. तनब न म सॳ िन-सा राफ एि सरल रॳखा म गतिमान वस िद िी गति व उसिॳ अनदप िu िी गई दरी िो सही प सॳ दााािा हॴ?

8. Which of the following graphs correctly

shows the speed and the corresponding distance covered by an object moving along a straight line?

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3. 22/7.







11. किसी नदी िी चााई 4.1 km हॴ। इस नदी पर बनॳ


1. 5.1 km 2. 4.9 km 3. 5.6 km 4. 5.4 km

11. A river is 4.1 km wide. A bridge built across it has 1/7 of its length on one bank and 1/8 of its length on the other bank. What is the total length of the bridge?



िोण OCB िा मान स uा होगा? 1. 60 2. 75 3. 55 4. 65 12. OA, OB, and OC are radii of the quarter


What is angle OCB? 1. 60 2. 75 3. 55 4. 65 13. तनजालीिरण सॳ पीडाि 12 किलोराम िॳ बछ चॳ िो


1. 7 2. 80 3. 120 4. 4

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13. Intravenous (IV) fluid has to be administered to a child of 12 kg with dehydration, at a dose of 20 mg of fluid per kg of body weight, in 1 hour. What should be the drip rate (in drops/min) of IV fluid? (1mg = 20 drops)





15. एि वव-अिीu स uा िॳ अि िा uोग 9 हॴ।


1. 36 2. 63 3. 45 4. 54

15. The sum of digits of a two-digit number is 9. If the fraction formed by taking 9 less than the number as numerator and 9 more than the number as denominator is 3/4, what is the number?



1. 500 कि.मी. रति घटा 2. 250 कि.मी. रति घटा 3. 750 कि.मी. रति घटा 4. दी गई सचनानदसार ञाि नही किuा जा

सििा।




information 17. िोई uजसि अपनी सामा u गति सॳ x% िॳज

चलिर सामा u समu सॳ y भमनट जल दी पहदचिा हॴ। uजसि िो सामाu गति सॳ चलनॳ पर कििना समu लगिा हॴ?

1. भमनट

2. भमनट

3. भमनट

4. भमनट

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17. If a person travels x% faster than normal, he reaches y minutes earlier than normal. What is his normal time of travel?

1. minutes

2. minutes

3. minutes

4. minutes





1. 30 2. 40 3. 50 4. 60 19. 12 cm ि ा 1 cm िी म uा िॳ लोहॳ िॳ दो गोल

िा वपघला िर सuदस ि किuा गuा हॴ। लोहॳ िी षति बना, दो नuॳ गोलॳ बनाuॳ गuॳ ह। गोल िी सभा u म uाए ह

1. 9 ि ा 4 cm 2. 9 ि ा 10 cm

3. 8 ि ा 5 cm 4. 2 ि ा 11 cm

19. Two iron spheres of radii 12 cm and 1 cm are


1. 9 and 4 cm 2. 9 and 10 cm 3. 8 and 5 cm 4. 2 and 11 cm 20. एि uजसि पuॳ 75/cL िी दर सॳ एल िोहोल

खरीद िर व उसम पानी भमला िर पuॳ 75/cL


1. 2:1 2. 1:2 3. 3:2 4. 2:3

20. A man buys alcohol at Rs. 75/cL, adds water, and sells it at Rs.75/cL making a profit of 50%. What is the ratio of alcohol to water?

1. 2:1 2. 1:2 3. 3:2 4. 2:3

Hkkx \PART 'B'

21. 10.5 bp रति फॳ रा िॳ सा 10 पणा फॳ र िॳ एि लघद

ववर जदि DNA अणद पर ववचार। DNA अणद िॳ िोर एि सा बॴठाuॳ जािॳ ह, िाकि एि ढीला व ि बन जाu। इस ढीलॳ व ि िी uोजि स uा होगी


molecule of 10 complete turns with 10.5 bp/turn. The ends of the DNA molecule are

sealed together to make a relaxed circle. This relaxed circle will have a linking number of

1. 105 2. 20.5 3. 10.0 4. 10.5

22.


1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4

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22.

In the above signalling cascade, which one of

the following molecules is denoted by ‘B’? 1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4 23. वॳस टना ाोण रuोग म रा भमि रतिरषषu िॳ







पािरण तनब न घटनाओ म सॳ किससॳ सामान uि: नह होगा?







1. Gain of function of oncogenes 2. Loss of function of tumor suppressors

3. Gain of function of genes involved in nucleotide excision repair

4. Loss of function of pro-apoptosis related genes







toxin? 1. Tetanus toxin 2. Botulinum toxin 3. Cholera toxin 4. Diptheria toxin 26. तनब न दाााuॳ आिा सॳ उपuदस ििम pH िो चदन

जजस पर अणद िॳ भलए ादि आवॳा ा u हो:



1. 2.02 2. 2.91 3. 5.98 4. 6.87

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27. रामचरन लॉट म, पॳ टाईा िॳ बारॳ म किuॳ गuॳ तनब न ि न म सॳ सही ि न चदन:





27. Choose the correct statement about peptides in

the Ramachandran plot.







1. 2. 3. 4.







1. 2. 3. 4.

29. ोरदार uाuाम िॳ बाद अतिररस ि ऑस सीजन िा

उपभोग इस िारण होिा हॴ:






exercise is












leaflet of the membrane to another

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3. Localize more negatively charged membrane proteins in the lipid bilayer

4. Cause uncoupling of v-SNARES and t- SNARES after fusion of incoming vesicle with target membrane

31. M अवस ा म समसमणी साईजसलन-CDK

गतिववतध भाखर पर पहदचिी हॴ। uह इस िारण कि





31. Mitotic cyclin-CDK activity peaks in M phase.

This is because 1. Mitotic cyclin is synthesised only in M

phase. 2. Threshold level of mitotic cyclin

accumulates only in late G2. 3. Cyclin subunit is activated by

phosphorylation only in M phase. 4. The kinase subunit is activated by

dephosphorylation only in M phase. 32. डाuोभलuोतuल (DO), डाuपालभमटोतuल (DP),














3. Transport from stroma into thylakoid space 4. Transport from mitochondrial intermembrane

space into the mitochondrial matrix 34. RNA पॉभलमरॳ II सॳ तनब न म सॳ िन-सॳ

अनदलॳझखि नह होिॳ?






by RNA polymerase II? 1. miRNA and some snRNA 2. miRNA and snoRNA 3. mRNA and snoRNA 4. tRNA and 5S rRNA 35. RNA सपादन जो एि प चानदलॳखनीu रकरuा हॴ







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35. RNA editing, a post-transcriptional process, is achieved with the help of guide RNA (g-RNA). Which one of the following statements about the process is NOT true?











36. Telomerase, a RNA-protein complex which

completes the replication of telomeres during DNA synthesis, is a specialised

1. RNA dependent DNA polymerase 2. DNA dependent DNA polymerase 3. DNA dependent RNA polymerase 4. RNA dependent RNA polymerase 37. चिद पादी पाद वविास हॳिद ाीास बदह: वचीu

िटि रॳरण आव uि हॴ। एि करuााील पाद िी सरचना िॳ भलuॳ तनब न म सॳ िन-सा आव uि नह हॴ?







1. Tbx genes and Wnt 2. Androsterone 3. Apoptotic genes 4. Fibroblast growth factor 38. किसी पादप मल िॳ बाu वचा सॳ अिस वचा िि



















aromatic amino acids. 2. electron transport from P680 to P700. 3. branched chain amino acid pathway. 4. electron transport from P700 to ferredoxin. 40. तनब न uतगि म सॳ िन-सा, वविीuि


1. भलजनन 2. इ डोल

3. रोपॳन 4. वपरोभल डीन 40. Which one of the following compounds is

NOT a part of alkaloid class of secondary metabolites?

1. Lignin 2. Indole 3. Tropane 4. Pyrrolidine

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41. तनब न ि न म सॳ िन-सा गलत हॴ?








produce four haploid megaspores 3. All the four megaspores undergo several

mitotic divisions to form female gametophyte in most angiosperms














2. uो uिा



43. Cell to cell communication is important in development of an organism. The ability of cells to respond to a specific inductive signal is called

1. Regional specificity of induction 2. Competence 3. Juxtracrine signalling 4. Instructive interaction 44. दाबरादहu िॳ उदीपन िॳ िारण तनब न म सॳ िन-







due to stimulation of baroreceptors? 1. Bradycardia 2. Hypotension 3. Venodilation 4. Vasoconstriction 45. जठररत म जस ि िोभािाओ िा िन-सा रिार,

दहस टाभमन िॳ मदस िन िॳ भलए उ िरदाuी हॴ?





45. Which type of cells located in gastric glands is

responsible for the release of histamine? 1. Mucous neck cells 2. Enterochromaffin-like cells 3. Chief cells 4. Parietal cells 46. तनब न पादपो प न सिॳ िन अणदओ म सॳ िन-सा





signalling molecules induces hyphal branching of arbuscular mycorrhizal fungi, a pheno-menon that is observed at the initial stages of colonization by these fungi?

1. Salicylic acid 2. Abscisic acid 3. Strigolactones 4. Systemin

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47. वॴसोरॳजससन राव इसिॳ सा नह बढिा:

1. uाuाम




47. Vasopressin secretion does NOT increase with 1. exercise 2. an increase in extracellular fluid volume 3. standing 4. vomiting 48. सीरम िी बनाबट आव uिि: लाामा िी बनावट







plasma EXCEPT that it lacks 1. Albumin 2. Stuart-Prower factor 3. Antihemophilic factor 4. Hageman factor 49. किसी जीन उ पाद म एिल एभमनो अब ल िॳ

पररविान म पररणभमि िरनॳ वाला तनब न उ पररविाजन म सॳ िन-सा अतिसभा uि: हॴ?







1. Acridine orange 2. X-rays 3. Ethylmethane sulphonate (EMS) 4. Ethidium bromide

50. uदद अधासमण I म अववuोजन घटिा हॴ, तनब न परर u म अतिसभा uि: िन-सा घटॳगा?




4. दो uद मि सामा u हगॳ ि ा दो n+1 हगॳ।

50. If non-disjunction occurs in meiosis I, which of the following scenario is most likely to occur?

1. Two gametes will be n+1 and two will be n-1 2. One gamete will be n+1, two will be ‘n’ and

one will be n-1 3. Two gametes will be normal and two will

be n-1 4. Two gametes will be normal and two will

be n+1 51. तनब न म सॳ िन-सा F लाज मड रखनॳवाली

िोभािाओ िॳ भलए सही हॴ?





51. Which of the following is true for cells

harbouring F plasmid? 1. Their F plasmid is non-functional. 2. They exhibit increased rates of transfer of


origin of replication is inactivated. 52. घघॳ (Limnaea peregra) िॳ ाख िॳ िद डलीभवन िी

ववरासि मािवाी हॴ, uह सदरतिजठि हॴ। दषषणाविा िद डलन रभावी एलील D पर तनभार हॴ ि ा वामाविा िद डलन अरभावी एलील d पर तनभार हॴ। दषषणाविा (Dd) रिार िी सिान मादा F1 िो नर वामाविा घोघ सॳ रसिररि किuा जािा हॴ। उसिॳ F2 सिान म ववमuद मी: समuद मी uजटu िा अनदपाि स uा होगा?

1. 3:1 2. 1:1 3. 1:3 4. 1:2:1


1. 3:1 2. 1:1 3. 1:3 4. 1:2:1

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53. जनस uा घन व िॳ फलन िॳ प म dN/dt िा रॳखातचम रदान िरिा हॴ एि





















55. Which of the following is a correct ranking of

ecosystems based on the root: shoot ratio of plants?





56. तनब न िल प म सॳ िन-सा “म सu िा uदग” माना जािा हॴ?














recessive at this locus 4. The population is effectively infinite in size 58. तनब न भवॴञातनि िल प म िन-सा स ितनu िॳ

पहलॳ आववभााव सॳ लषझणि हॴ?





1. Tertiary 2. Cretaceous 3. Permian 4. Triassic 59. एि स लोरोक फल a uदस ि ाॴवाल, जजसिा सचuी





4. पीिहररि ाॴवाल वगा

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59. An alga having chlorophyll a, floridean starch as storage product and lacking flagellate cells belongs to the class


नह हॴ?









3. पाररजाति 4. सरजाति 61. Individuals occupying a particular habitat and

adapted to it phenotypically but not genotypically are known as

1. Ecophenes. 2. Ecotypes. 3. Ecospecies. 4. Coenospecies. 62. तनब न ि न म सॳ िन-सा, जीवन इतिहास






62. Which one of the following statements supports the concept of trade-off in the evolution of life history traits?




tion leads to higher population growth 63. गहरॳ घाव िॳ भलए मानव िो दी जानॳ वाली टॴटानस

टीिा हॴ एि

1. DNA टीिा








1. 1200 ि ा 1250

2. 1200 ि ा 1500

3. 1350 ि ा 1500

4. 1250 ि ा 1350

64. The electrospray ionization spectrum of a

mixture of two peptides show peaks with m/z values 301, 401, 501, and 601. The molecular weights of the peptides are

1. 1200 and 1250 2. 1200 and 1500 3. 1350 and 1500 4. 1250 and 1350 65. एि रादटuॳ िॳ सा पाचन सॳ पवा ि ा प चाि




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1. Absorbance at 280 nm 2. Circular dichroism 3. Absorbance at 340 nm 4. Fluorescence value 66. भलग िॳ बीच रजननीu सफलिा पर अभभतच िा

परस पर ववरोध तनब न सगम िम म किसम राu: नह होगा?





1. Polyandry 2. Monogamy 3. Promiscuity 4. Polygamy 67. तनब न वव लॳिी ििनीि म किसम रिााीu

मापन सजबमभलि नह हॴ? 1. ELISA







1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab

68. Which genes have been introduced in Bollgard II cotton to get resistance against cotton bollworm, tobacco budworm and pink bollworm?

1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab 69. मानव िॳ ECG िो अकिि िरनॳ ववभभ न िार






69. Different leads are used to record ECG of

humans. Which one of the following is NOT unipolar leads?

1. Augmented limb leads 2. V1 and V2 leads 3. Standard limb leads 4. VR and VL leads 70. िोभािाओ म एि ववाॳ mRNA िी उपजस ति एव







mRNAs within a cell can be detected by 1. Northern blot analysis 2. RNase protection assay 3. in situ hybridization 4. real-time PCR

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Hkkx \PART 'C'

71. एि ही करuाधार पर दो अलग ए ाईम, X ि ा Y,









Which of the following statements is correct? 1. Only protein X is specific for the substrate, S 2. Only protein Y is specific for the substrate, S 3. Both X and Y are specific for the substrate, S 4. Both X and Y are non-specific for the substrate, S

72. पॳ टाईड-रोटीन सपण िॳ बारॳ म तनब न चार ि न ह:








1. A ि ा B 2. B ि ा C

3. A ि ा D 4. C ि ा D

72. The following are four statements on peptide/

protein conformation: A. Glycine has the largest area of conforma-

tionally allowed space in the Ramachandran plot of





Choose the combination of correct statements. 1. A and B 2. B and C 3. A and D 4. C and D 73. तनब न ि न म सॳ,





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1. A, B ि ा F

2. B, D ि ा E

3. A, C ि ा D

4. C, E ि ा F 73. From the following statements, A. Hydrogen, Deuterium and Tritium differ in




Helium E. Carbon-14 decays to Nitrogen-14 F. Carbon-14 decays to Carbon-13 pick the combination with ALL correct

statements. 1. A, B and F 2. B, D and E 3. A, C and D 4. C, E and F 74. uरीन िॳ जॴवस लॳण म :










C5 are from Glycine 3. Nl is from Aspartic acid; N3 from

Glutamine side-chain; N9 from N attached to C of Glutamine; N7, C4 and C5 are from Glycine


75. समववuदि बदद 6.5 िॳ एि रोटीन, जो िॴ जलाuम सॳ









a protein with an isoelectric point of 6.5 and also binds to calcium. This protein was subjected to four independent treatments: (i) pH 6.4, (ii) 10% glycerol, (iii) 10 mM CaCl2, (iv)

40% ammonium sulphate. This was followed by centrifugation and estimation of the protein in the supernatant. The results are depicted in the graph below:

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सभी गलत ि न िा सuोजन चदन: 1. A ि ा B 2. B ि ा C

3. C ि ा D 4. B ि ा D

76. From the following statements, A. For a reaction to occur spontaneously

the free energy change must be negative B. The interaction between two nitrogen

molecules in the gaseous state is predominantly electrostatic C. By knowing bond energies, it is possible to

deduce whether the bond is covalent bond or hydrogen bond

D. Hydrophobic interactions are not important in a folded globular protein


1. A and B 2. B and C 3. C and D 4. B and D

77. वविास िरिॳ E. coli िोभािाओ िॳ सा रतिजॴववि सॳफालॳजससन िो भमलानॳ पर, िोभािाओ िा ििदलन हो जािा हॴ, िप चाि अपघटन। सॳफा लॳजससन इसिा एि सदमि हॴ






1. protein synthesis 2. DNA synthesis 3. peptidoglycan synthesis 4. RNA polymerase 78. रतिदीजिि: लॳबभलि रोटीन, मीर म रोटीनराव िॳ

अ uuन िॳ भलए उपuोग म भलuा गuा। रतिदीजि तनब न म पाuी गई:





1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a)

78. Fluorescently tagged protein was used to study



sequence in which these events occur? 1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a) 79. uह सदतनजचि िरनॳ िॳ भलए कि माम पणाि: ससातधि

पररपस व mRNAs साईटोसॉल िि तनuााि होनॳ अनदमतिि ह, snRNPs िॳ सा सगि Pre -mRNAs



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1. B ि ा C 2. A ि ा D








Choose the correct combination of the possible

outcomes: 1. B and C 2. A and D 3. B and D 4. A and C 80. किसी रuोग म लाल रस ि िोभािाu अप घदटि िी


NaCl िॳ सा गददटिा तनिाली गuी ि ा कफर 100,000g पर अपिरीिरण किuा गuा। अतध लवी म तनबन रोटीन म सॳ िन-सा उपजस ि होगा?

1. बड 3 2. लाईिोफोरीन

3. G रोटीन uदजमि राही 4. स पॴजसरन 80. In an experiment, red blood cells were










81. In order to study the intracellular trafficking of

protein ‘A’, it was tagged with GFP (A-GFP). Fluorescence microscopy showed that A-GFP co-localizes with LAMP1. In the presence of bafilomycin A, an inhibitor of H+-ATPase, A-GFP does not co-localize with LAMP1. Instead, it co-localizes with LC3 puncta.

Which one of the following statements is TRUE?



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82. हररिलवि रिाuा िा सदमि ‘A’ हॴ। ‘A’ िॳ















83. G1 सॳ S िि िॳ एि िोभािा चर रगमन िॳ दरान साईस लीन D-CDK4, Rb िा फॉस फोररलीिरण िरिा हॴ ि ा E2F िॳ भलए उसिी बधदिा िो िम िरिा हॴ। Rb सॳ E2F अपघदटि होिा हॴ ि ा S-अवस ा जीन अभभ uजसि िो करuाजवि िरिा हॴ। रोटीन















cells in the following stages of cell cycle: (a) G1 phase, (b) G2 phase, (c) M phase. These cells were then grown in medium containing tritiated thymidine. Maximal amount of freshly labelled DNA is likely to be obtained in S-phase cells fused with

1. G1 phase cells 2. G2 phase cells 3. M phase cells 4. Both G1 and G2 phase cells

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85. टॳलोमॳरॳ, एि रोटीन-RNA सिद ल, िी एि ववभा ट उ रम राजसर टॳ गतिववतध हॴ जो DNA स लॳण िॳ दरान अ uाा िॳ रतिितिuन िो सपणा िरिी हॴ। uuवप उसिॳ िई गदणधमा DNA पॉभलमरॳ िॳ सा ह, िद ि भभ न भी ह। टॳलोमॳरॳ िॳ तनब न गदणधम म सॳ िन-सा DNA पॉभलमरॳ िॳ गदणधमा सॳ भभ न हॴ?













87. तनब न तचम म, िीन पररिाल पतनि अनदवाद सदमि िॳ

सा उपचाररि िोभािाओ िा पॉभलसोम पररछ िॳदन दाााuा गuा हॴ। uॳ िीन सदमि ह:




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Match the polysome profile to the inhibitor 1. (i) – a; (ii) – b; (iii) – c 2. (i) – b; (ii) – c; (iii) – a 3. (i) – c; (ii) – b; (iii) – a 4. (i) – a; (ii) – c; (iii) – b 88. स ितनu म, CG रचदर अनदरम सामा uि: C पर

मॴत लीिररि होिॳ ह, जो मनीिि जीन िो लॳबल िरनॳ िा एि िरीिा हॴ। uuवप रबधन जीन िॳ उ नाuि राu: CpG वीप िॳ सगि ह, ि ावप वॳ स ितनu म अभभ uस ि होिॳ ह। तनब न म सॳ िन-सा इसिी रॳ ठिम uा uा िरिा हॴ?















A B a. इटॳतरन (i) रस ि सररिा म ववभभ न

न वर, िोभािा-िोभािा आसजन अ uो uकरuाओ िो माजuि िरनॳवालॳ लॴजसटन


c. Ig-अतध

िद टद ब

(iii) Ca2+- तनभार रबल होमो-क फभलि िोभािा-िोभािा आसजन िो माजuि िरिा हॴ

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A B


b. Cadherin (ii) Contains extracellular Ig-like domains and are mainly involved in the fine tuning of cell-cell adhesive interactions during development and regeneration.

c. Ig-super- family









िॳ बारॳ म किuॳ गuॳ तनम न ि न म सॳ िन-सा सही नह हॴ ?










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92. उभuचर िॳ ववu म, प ठeu ओ ठ िोभािाu ि ा

उनि सजाि “स पॳमन-मानगोल ा uवस ापि” िहलािॳ ह। “ uवस ापि” सॳ सबतधि तनब न ि न किuॳ गuॳ:







1. A ि ा D 2. D ि ा E

3. A ि ा E 4. B ि ा C









िोभािी समदरी अतचान रण िॳ सा जदटल पदनuोजन सजबमभलि ा। uह ववतध साधारणि:

अि चमा बनानॳ िॳ भलए भाजuि षॳम म रहिॳ िरि िो अनदमातनि बदह चमा षॳम िॳ अदर अदल-

बदल िरिी ी। uदद िरिीu तनणााuि िा अलगीिरण घदटि हदआ, पररणभमि रण िो अ uवजस ि होना चादहए। परिद डरuॳा नॳ इन रण सॳ सामा u डडभि पाuॳ। सभा u uा uाu ह:






1. माम A 2. माम D

3. माम A ि ा B 4. A, C ि ा D 93. Driesch performed the famous “pressure plate”

experiment involving intricate recombination with an 8-celled sea urchin embryo. This procedure reshuffled the nuclei that normally would have been in the region destined to form endoderm into the presumptive ectoderm region. If segregation of nuclear determinants had occurred, the resulting embryo should have been disordered. However, Driesch obtained normal larvae from these embryos. The possible interpretations regarding the 8-celled sea urchin embryo are:

A. The prospective potency of an isolated blastomere is greater than its actual prospective fate.



D. Regulative development occurs where location of the cell in the embryo determines its fate.

Which of the above interpretation(s) is/are true? 1. Only A 2. Only D 3. Only A and B 4. A, C and D

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94. समदरी अतचान अड िॳ तनॳचन िॳ दरान घटनॳवाली तनब न घटनाओ पर ववचार:














Which of the above statement(s) is NOT true? 1. Only C 2. A and C 3. Only D 4. B and D 95. स िनी रण िॳ वविास िॳ दरान भलuॳ जानॳ वालॳ

तनणाu िॳ बारॳ म तनब न ि न ददuॳ गuॳ।

A. आिररि िोभािा र uभार (ICM) िी अनॳिाजसि िीन अनदलॳखन िारि Oct 4, Sox 2

ि ा Nanog िॳ एि रोा सॳ बनाuॳ रखी जािी हॴ।





1. A ि ा B 2. A ि ा C










1. CED-4, Apaf -1 सॳ साम u रखिा हॴ।




for proper formation of different structures. In C. elegans, apoptosis is accentuated by ced-3 and ced-4 genes, which in turn are negatively

regulated by ced-9 and eventually EGL-1. When compared to mammals, functionally similar homologues have been identified. Accordingly, which one of the following statements is NOT correct?

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97. राईपनोसोम म, एि 35 षार रॳिा अनदरम िई

भभ न अनदलॳख िॳ सा जोाा जािा हॴ, िाuााील mRNAs िो बनािॳ हदuॳ। नॳिा अनदरम अ u RNAs

िॳ सा इस वारा जोाा जािा हॴ:









an internal A present in the leader sequence 98. िद ि ववितिजन स िभ A म ि ा स िभ B म रतिरषी

अनदकरuा सॳ बचनॳ िॳ भलए उनसॳ उपuोग म भलए जानॳ वालॳ िद ि अवविीu ररम तनब नवि सचीिि ह:

A B a. Trypanosoma








1. a – (i), b – (ii), c – (iii)

2. a – (ii), b – (iii), c – (i)

3. a – (iii), b – (i), c – (ii)

4. a – (i), b – (iii), c – (ii)


A B

a. Trypanosoma brucei

(i) Capable of employing unusual genetic processes by which they generate extensive variations in their variant surface glycoproteins (VSG)







1. a – (i), b – (ii), c – (iii) 2. a – (ii), b – (iii), c – (i) 3. a – (iii), b – (i), c – (ii) 4. a – (i), b – (iii), c – (ii)

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99. दो स टॴराइा हामोन रादहu X ि ा Y म एि सल नी आबधन षॳम ि ा एि DNA आबधन षॳम उपजस ि ह। पदनuोगज DNA ििनीिी िॳ उपuोग सॳ एि पररवतिाि हाईरा राही H िॴuार किuा जािा हॴ िाकि उसम X िा सल नी आबधन षॳम ि ा Y िा

DNA आब धन षॳम उपजस ि ह। िप चाि रादहu X, Y ि ा H िो अतिअभभ uस ि िरिी िोभािाओ िॳ िीन समदछ चu िो अलग सॳ हामोन X uा हामोन Y िॳ सा उपचार किuा गuा। uह मानिॳ हदए कि िोई तिuाि-अभभकरuिा नही हॴ, तनब न आलॳख म सॳ िन-सा, हर ववu म राही-सल नी आबधन िा रॳ ठिम रतितनतध व िरिा हॴ?

99. Two steroid hormone receptors X and Y both

contain a ligand binding domain and a DNA binding domain. Using recombinant DNA technology, a modified hybrid receptor H is prepared such that it contains the ligand binding domain of X and DNA binding domain of Y. Three sets of cells over-expressing receptors X, Y and H were then treated separately either with hormone X or with hormone Y. Assuming that there is no cross-reactivity, which one of the following graphs best represent the receptor-ligand binding in each case?

100. रोटीन Y िॳ सा सिद भलि िरिॳ साईटोसॉल म एि

रोटीन X िो सकरu अवस ा म रखा जािा हॴ। किसी रतिबल उ िॳजन िॳ अधीन, Y फॉस फोररभलि हो जािा हॴ, ि ा उसिा रोदटuोसोमल अविा हो जािा हॴ। X मदस ि हो जािा हॴ, िरि म स ानािररि हो जािा हॴ, ि ा एपो टोभसस वारा िोभािा म uद िरनॳवालॳ जीन िॳ अनदलॳखन म पररणभमि होिा हॴ। तनब न चार अलग ववu म रतिबल उ िॳजन ददuा गuा:-






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Which one of the following graphs best

describes the apoptotic state of the cells in the above cases? Y-axis represents % apoptotic cells.














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The reasons for difference in the pattern of

alveolar gas exchange of N2O and CO have been proposed in the following statements:






103. भमतरि िमिा पर बाu दाब िनॳ िी सवॳदना िी

षति िारझणि िरिा हॴ जबकि सापॳषि: ददा सवॳदना अटट रहिा हॴ। उसी िमिा पर स ानीu तन चॳिि



B. स ानीu तन चॳिि वह व uासी िमिा रॳखाओ म आवॳग िी चालििा िो िम िरिॳ ह।




1. A ि ा B 2. C ि ा D


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103. External pressure given on a mixed nerve causes loss of touch sensation while pain sensation remains relatively intact. On the other hand, application of local anaesthetics on the same nerve, induces loss of pain sensation keeping touch sensation least affected. These observations can be explained by the following statements:




Which of the above statement(s) is/are

INCORRECT ? 1. A and B 2. C and D 3. Only C 4. Only D






104. The probable effects of lesion of left optic tract

on the vision of a human subject are given below. Identify the correct statement.





105. पद पाग वविास िॳ रतिमान िो पद प िॳ आस न

चस िर म समापवधी जीन िी uजसिगि एव आछ िाददि अभभ uजसि तनधााररि िरिी हॴ। एि एराबडोजसस उ पररविी म पद पाग तनब नवि बदटि ह:













A. B. C. D.


1. A ि ा B 2. B ि ा C

3. C ि ा D 4. A ि ा D



A. B. C. D.


correct? 1. A and B 2. B and C 3. C and D 4. A and D

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1. A, B ि ा C 2. B, C ि ा D

3. A, B ि ा D 4. A, C ि ा D











B. पररधीu पणाम uोिि िोभािाओ म फॉस फोईनाल पाईवॳट िॉबााजससलॳस वारा वाuदमडलीu CO2

जस रीिररि हो हॴ, एि चार िॉबान अब ल दॳिॳ हदuॳ।

C. पणाम uोिि िॳ आिररि परि म चार िॉबान अब ल िो NAD-मॴभलि ए ाईम वविॉबााजससलीिरण िरिॳ CO2 िो मदस ि िरिा हॴ।

D. CO2 कफर सॳ पलाछ िद िोभािाओ म िॴ जलवन चर वारा पदन:जस रीिररि होिा हॴ।


1. B, C ि ा D 2. A, B ि ा C

3. A, B ि ा D 4. A, C ि ा D















1. A, B ि ा C 2. A, C ि ा D

3. A, B ि ा D 4. B, C ि ा D

109. Read the following statements related to plant-

pathogen interaction A. Systemic acquired resistance is observed

following infection by compatible pathogen B. Induced systemic resistance is activated following infection by compatible pathogen

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C. A bacterial infection can induce effector triggered immunity (ETI) leading to hypersensitive response locally D. NPR1 monomers that are released in cytosol due to salicylic acid accumulation is rapidly translocated to nucleus









1. माम A ि ा C 2. माम B ि ा C

3. माम B ि ा D 4. माम A ि ा B









111. पादपहामोन िॳ नाम स िभ I म ि ा उनसॳ सगि पहल/रभाव/रिाuा स िभ II म तनब न ददuॳ गuॳ ह

I II

A ऑस सीन (i) ववलबि पणा जीणािा







I II









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a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -






a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -





2. रतिलोमन ववमuद मी, अ ााि एि रतिभलवप सामा u गदणसम ि ा उसिा समजाि रतिलोमन िॳ सा , ववतनमu िो अनदमि नही िरिॳ स uकि वॳ िदावप uदजमि नही हो सििॳ।



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114. Inversions are considered as cross-over suppressors because

1. Homozygous inversions are lethal and thus they do not appear in next generation

2. Inversion heterozygotes, i.e., one copy having normal chromosome and its homologue having inversion, does not allow crossing over to occur as they cannot pair at all



115. तनब न वाावली किसी ववाॳि िॳ वाागति रतिमान

िो दााािी हॴ।

वाागति िी ढग ि ा इसिी रातuििा कि III पीढी म पदमी वह ववाॳि दाााuॳगी, इनिा अनदमान िीजजuॳ।


3. अभलगसमी अरभावी, रातuििा 1/2 हॴ।



From the following, select the possible mode

of inheritance and the probability that the daughter in generation III will show the trait.


116. िीन met– E. coli उ पररविी रभॳद अलग किuॳ गuॳ।

उ पररविान िॳ स वभाव िॳ अ uuन हॳिद इन उ पररविी रभॳद िा EMS uा रोलॳववनस उ पररविाजन िॳ सा उपचार किuा गuा, ि ा

र uावि िॳ भलए अकिि किuा गuा। पररणाम तनब नवि साराभाि ह:


EMS Proflavin

A - + B + - C - -















116. Three met– E. coli mutant strains were isolated.

To study the nature of mutation these mutant strains were treated with mutagens EMS or proflavins and scored for revertants. The results obtained are summarized below:


EMS Proflavin

A - + B + - C - -




1. A-Transversion B- Insertion or deletion of a single base C- Deletion of multiple bases

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2. A-Transition B- Transversion C- Insertion or deletion of a single base 3. A-Insertion or deletion of a single base B- Transition C- Deletion of multiple bases 4. A- Transition B- Insertion or deletion of multiple bases C- Transversion

117. ऐरीनल वल िद ट िॳ ोना लोमॳलोसा म स टॴराईडजतनि प िो तनब न तचम दााािा हॴ।









118. एि ास u पादप म ऐलील िा एि uदगल बीज आमाप िो तनधााररि िरिा हॴ। मोटी बीज िॳ भलए उ िरदाuी ‘B’ ऐलील िोटी बीज िॳ भलuॳ उ िरदाuी ‘b’ ऐलील सॳ रभावी हॴ। इस परीषण िॳ भलए कि स uा एि पहचातनि रभावी DNA तचनि (5kb बड) बीज आमाप िो तनuमि िरनॳ वालॳ ऐलील िॳ सा सहलजनि हॴ, एि रuोग किuा गuा। दोन ऐलील और DNA तच ह िॳ भलए ववमuद मी एि पादप सॳ एि िोटी बीज पादि जजसम 5kb बड नही uा सा रसिररि किuा गuा। रसिरण रा ि 100 सिान िा वव लॳण DNA तचनि िी उपजस ति ि ा अनदपजस ति िॳ भलए किuा गuा। पररणाम तनब न िाभलिा म अकिि ह:








22

23

27

28








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22

23

27

28




bold seed but is linked to the small seed trait














120. आप uह रॳषण िरिॳ ह कि नाितचमटी िी दो रजातिuा, रजाति 1 ि ा रजाति 2, अिरा वारीu ाॴल िी रमा: ऊपरी ि ा तनचली परि म तनवास िरिी ह। जब आपसॳ रजाति 2 तनचली परि सॳ तनिाल दी जािी हॴ, िभी रजाति 1 ऊपरी ि ा तनचली, दोन परि म तनवास िर सििी हॴ। इन रॳषण सॳ आपिा तन िा तनब न ददuॳ गuॳ वविल प म सॳ स uा होगा?











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122. ाीिो ण घासभभमu िॳ सही स ानीu नाम िो

अपनॳ भगोलीu पररसर िॳ सा सदमॳभलि िर:











123. किसी रजाति िॳ भलए पररिजलपि जीवन िाभलिा

तनब नवि हॴ:



(nx)


(dx)


(lx)


0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0



Age class (x)

Number alive (nx)

Number dying (dx)

Age specific

survivor-ship (lx)


(mx)

0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0









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125. रजाति-रचदरिा (X-अष) ि ा समददाu सॳवा (Y-अष)

िॳ बीच सभा u सबध िी uा uा हॳिद रस िाववि ववभभ न पररिल पनाओ िॳ आलॳखीu रतितनतध व तनब नवि ह।





िद जीभाला 4. (a) िीलि, (b) िद जीभाला, (c) अतिररस ििा, (d)


125. Following are the graphical representations of

various hypotheses proposed for explaining the possible relationships between species richness (X-axis) and community services (Y-axis).

Which of the following options is the correct

match between the graphical representations and the hypotheses?





Idiosyncratic

126. तनब न तचम तनब न ववभभ न समu बददओ पर जॴव लu िा रतितनतध व िरिा हॴ: SR = सuोदu; N =


ऊपर ददए गए तचम म िनसा समuबि जॴव लu रतितनतध व िरिा/िरिॳ हॴ/ह?

1. तचम B

2. तचम A ि ा C

3. तचम C ि ा D

4. तचम D

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126. Following are the plots representing biological rhythms at different time points depicted as:

SR = Sunrise; N = Noon; SS = Sunset; MN = Midnight

Which of the plot(s) represent the ultradian

biological rhythm(s)? 1. Plot B 2. Plots A and C 3. Plots C and D 4. Plot D



















128. Given below is a graphical representation of

changes in morphological features over a period of geological time scale, where population A accumulates heritable morphological changes and give rise to a distinct species B. Population B splits into a distinct species B2



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1. 81% 2. 49% 3. 42% 4. 18%


1. 81% 2. 49% 3. 42% 4. 18%

130. िीन अलग Hfr रभॳद िॳ उपuोग सॳ अिरातuि सगम रuोग किuॳ गuॳ। िीन (1 -3) रभॳद वरणीu तचनि िॳ अलग सuोजन रखिॳ ह। तनब न िाभलिा म हर रभॳद िॳ भलए हर तचनि िा रवॳा समu दाााuा गuा हॴ।


(5’) thr (17’)

strr

(25’) phe (30’)

pro (45’)

Hfr #2 strr

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)


1. met-thr-strr-phe-pro-pur r-his 2. purr-pro-his-met-thr-strr-phe 3. strr-purr-his-met-phe-pro-strr




(5’) thr (17’)

str r

(25’) phe (30’)

pro (45’)

Hfr #2 str r

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)

Using the above data, predict the correct seque-

nce of markers on the E. coli chromosome. 1. met-thr-str r-phe-pro-purr-his 2. pur r-pro-his-met-thr-str r-phe 3. str r-pur r-his-met-phe-pro-str r







131. Peripatus is an interesting living animal having

unjointed legs, nephridia, haemocoel, trachea, dorsal tubular heart, claws, jaws, continuous muscle layers in body wall. This is considered as a connecting link between





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132. तनब न uवस ा मि तचम आविबीजजu म वविीuि वविास िा रतितनतध व िरिा हॴ।





132. The following schematic diagram represents

secondary growth in the angiosperms.



1. A – Inter-fascicular, B – Fascicular, C –

Vascular, D – Cork 2. A – Fascicular, B – Inter-fascicular, C –

Vascular, D – Cork 3. A – Cork, B – Inter-fascicular, C –

Fascicular, D – Vascular 4. A – Cork, B – Fascicular, C – Inter-

fascicular, D – Vascular

133. तनब न िाभलिा रमदख िविी समह ि ा उनिॳ लषण िी सची रदान िरिी हॴ:














Which one of the following options represents

the appropriate match between the fungal group and their characteristics?


134. एि जॴववॴञातनि होिर आप िीन टॴस सा A, B ि ा

C िा वगीिरण िरना चाहिॳ ह। आपिॳ पास िीन ववाॳि p, q ि ा r िॳ बारॳ म सचना हॴ। ववाॳि जो पॴिि हॴ, ‘0’ तगना जािा हॴ ि ा ववाॳि जो uदिप न हॴ, ‘1’ तगना जािा हॴ। िीन टॴस स म पाuॳ गuॳ ववाॳि िा बटन तनब नवि हॴ:

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A B C p 1 1 0 q 1 1 0 r 0 1 1









A B C p 1 1 0 q 1 1 0 r 0 1 1







रोग









A Bordetella




wheat D Anaplasma


cough in humans






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Which one of the following statements is

correct? 1. CD is more sensitive to structural changes

than fluorescence 2. Fluorescence is more sensitive to structural

changes than CD 3. Both methods are equally responsive to

structural changes 4. Acrylamide alters the secondary structure of

the protein

137. पॉभल uजसलuोटाइा ाखलाओ िॳ अफॉस फोररलीिि 5 - भारा िॳ फॉस फोररलीिरण वारा DNA uा RNA







137. Polynucleotide kinase (PNK) is frequently used

for radiolabeling DNA or RNA by phosphory-lating 5 - end of non-phosphorylated polynucleo-tide chains. Which of the following statement about PNK is NOT true?




138. T7 RNA पॉभलमरॳ उ नाuि ि ा lac सिारि िॳ

अिगाि रोटीन X िॳ भलए िटलॳखन िरिॳ एि जीन िो एि अभभ uजसि सवाहि म स लोतनि किuा गuा। 37C पर 6 घटॳ िॳ भलए 1 mM IPTG िॳ भमलानॳ सॳ िोभािाu रॳररि िी गuी। िोभािाओ िॳ लuन िरिॳ अववलॳu वपड ि ा िोभािा-मदस ि अतध लावी म अपिरीिरण वारा रभाजजि किuॳ गuॳ। अववलॳu वपड म रोटीन X उपजस ि हॴ। (िोभािा-मदस ि अतध लावी) ववलॳu रभाग म रोटीन X िो अभभ uस ि िरनॳ िॳ रu न म नीचॳ ददए गए िन-सी uदिनीति िा आप उपuोग िरगॳ?





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138. A gene encoding for protein X was cloned in an expression vector under the T7 RNA polymerase promoter and lac operator. Cells were induced by the addition of 1 mM IPTG at 37C for 6 h. Cells were lysed and fractionated into insoluble bodies and cell-free supernatant by centrifugation. Protein X is present in the insoluble bodies. Which one of the following strategies would you use to express protein X in the soluble fraction (cell-free supernatant)?










C. ए ाईम ‘5’ िॳ भलए करuाधार िा पररसीमन

पारजीनी पादप म X िी मामा म अनदपािी ववि िॳ न पाuॳ जानॳ िॳ सभाववि िारण िा उपरोस ि ि न म सॳ िन-सॳ रतितनतध व िर सििॳ ह?











140. िविी रतिरोध िॳ भलए पारजीन ‘A’ रखनॳवालॳ एि एिल रतिभलवप समuद मज पारजीनी पादप िो बाद म लवण-रतिबल दॳनॳ िॳ भलए एि दसरॳ जीन ‘B’ िॳ सा पदन: पािररि किuा गuा। दोन पािरण रuोग म िाम म भलuॳ जानॳ वालॳ वरण तचनि जीन अलग ॳ। पदन: पािरण रuोग सॳ पाuॳ गuॳ पारजीनी पादप िो लवण-रतिबल रतिरोध िॳ भलए परीषषि किuा गuा ि ा सदना-सिरण वारा एिल

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रतिभलवप घटनाu पहचानी गuी। uॳ एिल रभलभलवप घटनाu स वतनॳतचि ी। सभी पारजीनी पादप म दो T-DNAs (A ि ा B पारजीन िो अिववाजटि) िॳ असलजनि स ान पर समािलन होनॳ पर T1 सिान म लषणरपी अनदपाि हगॳ:





140. A single copy homozygous transgenic plant containing the transgene ‘A’ for fungal resistance was subsequently re-transformed with another gene ‘B’ for conferring resistance to salt-stress. The selection marker genes used for both the transformation experiments were different. Transgenic plants obtained following the re-transformation experiment were screened for salt-stress resistance and single copy events were identified by Southern hybridization. These single copy events were self-pollinated. In the event of the two T-DNAs (containing the A and B transgenes) getting integrated in unlinked locations in all the transgenic plants, the phenotypic ratios among the T1 progeny would be:

1. 3 (Fungal resistant + Salt-stress resistant): 1

(Fungal resistant) 2. 1 (Fungal resistant): 2 (Fungal resistant +

Salt-stress resistant): 1 (Salt-stress resistant)

3. 3 (Salt-stress resistant): 1 (Fungal resistant) 4. 1 (Fungal resistant): 1 (Salt-stress

resistant):1 (Fungal resistant + Salt stress resistant)




BamHI (H+B) ि ा HindIII plus PstI (H+P) िॳ

उपuोग सॳ लाज मड िॳ रतिबधन-पाचन वारा आप सही वव uास िॳ स लोन िॳ भलए परीषण िर रहॳ ह। सवाहि िॳ उतचि राि िा मानतचम तनब न दाााuा गuा हॴ।


ऊपर दाााuॳ गuॳ लाज मा म िन-सा, सही वव uास वालॳ ि लोन िा रतितनतध व िरिा हॴ?

1. A 2. B 3. C 4. D


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Given below is the pattern following restriction digestion of plasmid isolated from four independent clones (A, B, C or D).



142. 6129 uजसिu िी एि आबादी म M-N तधर

रिार िी बारबाररिा तनब नवि हॴ:


















before divergence of vertebrates 3. Exon shuffling exclusively produced such

cluster 4. Whole genome duplications could lead to

such observations

144. किसी झिल ली म अणदओ िॳ ववसरण िॳ आिलन िॳ भलए एि ववतध हॴ रिाा-ववरजन िॳ उपराि रतिदीजि पदन:राजि (FRAP) हॴ। ऐसॳ रति दीजिि: लॳबभलि अणद




iv. झिल ली िी सिह िॳ सा बतधि होनॳवाला एि तचजनि रोटीन





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144. Fluorescence recovery after photobleaching (FRAP) is a method to estimate the diffusion of molecules in a membrane. Fluorescently labelled molecules such as





coefficients. The following data were obtained:
















destruction in proteasomes Which one of the following combinations of

proteins functions inside the plant cells? 1. Only A and C 2. A, B and C 3. Only B and C 4. A, B and D

FOR ROUGH WORK

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vuqns’k


2. vksñ,eñvkjñ mRrj i=d vyx Lks fn;k x;k gS A viuk jksy uEcj vkSj dsUnz dk uke fy[kus Lks igys ;g tkap yhft, fd iqfLrdk esa i”B iwjs vkSj lgh gSa rFkk dgha Lks dVs&QVs ugha gSa A ;fn ,slk gS rks vki bfUothysVj Lks mlh dksM dh iqfLrdk cnyus dk fuosnu dj ldrs gSa A blh rjg Lks vksñ,eñvkjñ mRrj i=d dks Hkh tkap ysa A bl iqfLrdk esa jQ dke djus ds fy, vfrfjDr iUus layXu gSa A







OMR mRrj i=d lkSaius ds i’pkr vki bldh dkWcZuySl izfrfyfi ys tk ldrs gSaA 11. fgUnh ek/;[email protected] ds iz’u esa folaxfr gksus@ik;s tkus ij vaxzsth laLdj.k izekf.kd gksxk A


Øekad




jksy uacj :…………………………..

uke :...........................................

2016 (II)


H 3 C fo”k; dksM iqfLrdk dksM

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FOR ROUGH WORK

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3

Hkkx \PART 'A'

1. किसी एि रजाति िॳ दो तिलचट ह, जजनिी














नीचॳ ददuॳ गuॳ पाई-तचम म सॳ िन-सा इस जानिारी िो सही दााािा हॴ?




3. ि ा Q िॳ मापन सबतधि uाजछिि अादविuा

रमा: 10% ि ा 2% ह। P/Q म रतिाि uाजछिि अादवि कििनी हॴ?




िो uवजस ि किuा जा सििा हॴ? 1. 120 2. 720 3. 360 4. 240

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4. In how many distinguishable ways can the letters of the word CHANCE be arranged?

1. 120 2. 720 3. 360 4. 240 5. लापिा रतिमान िो ञाि िीजजuॳ?



व आuिन म 10% िी ववि होिी हॴ। बीज िा घन व कििनॳ गदणाि सॳ बढॳगा?







1. 2. 3. 4. 8. किसी नदी िी चााई 4.1 km हॴ। इस नदी पर बनॳ


1. 5.1 km 2. 4.9 km 3. 5.6 km 4. 5.4 km 8. A river is 4.1 km wide. A bridge built across

it has 1/7 of its length on one bank and 1/8 of its length on the other bank. What is the total length of the bridge?



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िोण OCB िा मान स uा होगा?

1. 60 2. 75 3. 55 4. 65 9. OA, OB, and OC are radii of the quarter


What is angle OCB? 1. 60 2. 75 3. 55 4. 65 10. तनजालीिरण सॳ पीडाि 12 किलोराम िॳ बछ चॳ िो


1. 7 2. 80 3. 120 4. 4 10. Intravenous (IV) fluid has to be administered

to a child of 12 kg with dehydration, at a dose of 20 mg of fluid per kg of body weight, in 1 hour. What should be the drip rate (in drops/min) of IV fluid? (1mg = 20 drops)





12. तनब न म सॳ िन-सा राफ एि सरल रॳखा म

गतिमान वस िद िी गति व उसिॳ अनदप िu िी गई दरी िो सही प सॳ दााािा हॴ?

12. Which of the following graphs correctly shows the speed and the corresponding distance covered by an object moving along a straight line?

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3. 22/7.







15. िोई uजसि अपनी सामा u गति सॳ x% िॳज

चलिर सामा u समu सॳ y भमनट जल दी पहदचिा

हॴ। uजसि िो सामाu गति सॳ चलनॳ पर कििना समu लगिा हॴ?

1. भमनट

2. भमनट

3. भमनट

4. भमनट

15. If a person travels x% faster than normal, he

reaches y minutes earlier than normal. What is his normal time of travel?

1. minutes

2. minutes

3. minutes

4. minutes





1. 30 2. 40 3. 50 4. 60 17. 12 cm ि ा 1 cm िी म uा िॳ लोहॳ िॳ दो गोल

िा वपघला िर सuदस ि किuा गuा हॴ। लोहॳ िी षति बना, दो नuॳ गोलॳ बनाuॳ गuॳ ह। गोल िी सभा u म uाए ह

1. 9 ि ा 4 cm 2. 9 ि ा 10 cm

3. 8 ि ा 5 cm 4. 2 ि ा 11 cm

17. Two iron spheres of radii 12 cm and 1 cm are


1. 9 and 4 cm 2. 9 and 10 cm 3. 8 and 5 cm 4. 2 and 11 cm

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18. एि uजसि पuॳ 75/cL िी दर सॳ एल िोहोल खरीद िर व उसम पानी भमला िर पuॳ 75/cL


1. 2:1 2. 1:2 3. 3:2 4. 2:3 18. A man buys alcohol at Rs. 75/cL, adds water,

and sells it at Rs.75/cL making a profit of 50%. What is the ratio of alcohol to water?

1. 2:1 2. 1:2 3. 3:2 4. 2:3 19. एि वव-अिीu स uा िॳ अि िा uोग 9 हॴ।


1. 36 2. 63 3. 45 4. 54 19. The sum of digits of a two-digit number is 9.

If the fraction formed by taking 9 less than the number as numerator and 9 more than the number as denominator is 3/4, what is the number?



1. 500 कि.मी. रति घटा 2. 250 कि.मी. रति घटा 3. 750 कि.मी. रति घटा 4. दी गई सचनानदसार ञाि नही किuा जा सििा।




information

Hkkx \PART 'B'

21. RNA सपादन जो एि प चानदलॳखनीu रकरuा हॴ







21. RNA editing, a post-transcriptional process, is

achieved with the help of guide RNA (g-RNA). Which one of the following statements about the process is NOT true?











22. Telomerase, a RNA-protein complex which

completes the replication of telomeres during DNA synthesis, is a specialised

1. RNA dependent DNA polymerase 2. DNA dependent DNA polymerase 3. DNA dependent RNA polymerase 4. RNA dependent RNA polymerase

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23. 10.5 bp रति फॳ रा िॳ सा 10 पणा फॳ र िॳ एि लघद ववर जदि DNA अणद पर ववचार। DNA अणद िॳ िोर एि सा बॴठाuॳ जािॳ ह, िाकि एि ढीला व ि बन जाu। इस ढीलॳ व ि िी uोजि स uा होगी


molecule of 10 complete turns with 10.5 bp/turn. The ends of the DNA molecule are sealed together to make a relaxed circle. This relaxed circle will have a linking number of

1. 105 2. 20.5 3. 10.0 4. 10.5

24.


1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4 24.

In the above signalling cascade, which one of the following molecules is denoted by ‘B’?

1. STAT 5 2. SMAD 6 3. GSK3 4. SMAD 4 25. वॳस टना ाोण रuोग म रा भमि रतिरषषu िॳ







पािरण तनब न घटनाओ म सॳ किससॳ सामा uि: नह होगा?







1. Gain of function of oncogenes 2. Loss of function of tumor suppressors 3. Gain of function of genes involved in

nucleotide excision repair 4. Loss of function of pro-apoptosis related

genes







toxin? 1. Tetanus toxin 2. Botulinum toxin 3. Cholera toxin 4. Diptheria toxin

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28. ोरदार uाuाम िॳ बाद अतिररस ि ऑस सीजन िा उपभोग इस िारण होिा हॴ:






exercise is












leaflet of the membrane to another 3. Localize more negatively charged

membrane proteins in the lipid bilayer 4. Cause uncoupling of v-SNARES and

t-SNARES after fusion of incoming vesicle with target membrane

30. M अवस ा म समसमणी साईजसलन-CDK गतिववतध

भाखर पर पहदचिी हॴ। uह इस िारण कि





30. Mitotic cyclin-CDK activity peaks in M phase.

This is because 1. Mitotic cyclin is synthesised only in M

phase. 2. Threshold level of mitotic cyclin

accumulates only in late G2. 3. Cyclin subunit is activated by

phosphorylation only in M phase. 4. The kinase subunit is activated by

dephosphorylation only in M phase. 31. तनब न दाााuॳ आिा सॳ उपuदस ििम pH िो चदन

जजस पर अणद िॳ भलए ादि आवॳा ा u हो:



1. 2.02 2. 2.91 3. 5.98 4. 6.87

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32. रामचरन लॉट म, पॳ टाईा िॳ बारॳ म किuॳ गuॳ तनब न ि न म सॳ सही ि न चदन:





32. Choose the correct statement about peptides in the Ramachandran plot.







1. 2. 3. 4.







1. 2. 3. 4.

34. डाuोभलuोतuल (DO), डाuपालभमटोतuल (DP),














3. Transport from stroma into thylakoid space 4. Transport from mitochondrial

intermembrane space into the mitochondrial matrix

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36. RNA पॉभलमरॳ II सॳ तनब न म सॳ िन-सॳ अनदलॳझखि नह होिॳ?






by RNA polymerase II? 1. miRNA and some snRNA 2. miRNA and snoRNA 3. mRNA and snoRNA 4. tRNA and 5S rRNA 37. चिद पादी पाद वविास हॳिद ाीास बदह: वचीu िटि

रॳरण आव uि हॴ। एि करuााील पाद िी सरचना िॳ भलuॳ तनब न म सॳ िन-सा आव uि नह हॴ?







1. Tbx genes and Wnt 2. Androsterone 3. Apoptotic genes 4. Fibroblast growth factor 38. तनब न ि न म सॳ िन-सा गलत हॴ?








produce four haploid megaspores

3. All the four megaspores undergo several mitotic divisions to form female gametophyte in most angiosperms














2. uो uिा



40. Cell to cell communication is important in

development of an organism. The ability of cells to respond to a specific inductive signal is called

1. Regional specificity of induction 2. Competence 3. Juxtracrine signalling 4. Instructive interaction 41. तनब न uतगि म सॳ िन-सा, वविीuि


1. भलजनन

2. इ डोल

3. रोपॳन

4. वपरोभल डीन

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41. Which one of the following compounds is NOT a part of alkaloid class of secondary metabolites?

1. Lignin 2. Indole 3. Tropane 4. Pyrrolidine 42. किसी पादप मल िॳ बाu वचा सॳ अिस वचा िि



















aromatic amino acids. 2. electron transport from P680 to P700. 3. branched chain amino acid pathway. 4. electron transport from P700 to ferredoxin.

44. वॴसोरॳजससन राव इसिॳ सा नह बढिा:

1. uाuाम




44. Vasopressin secretion does NOT increase with 1. exercise 2. an increase in extracellular fluid volume 3. standing 4. vomiting 45. दाबरादहu िॳ उदीपन िॳ िारण तनब न म सॳ िन-







due to stimulation of baroreceptors? 1. Bradycardia 2. Hypotension 3. Venodilation 4. Vasoconstriction 46. सीरम िी बनाबट आव uिि: लाामा िी बनावट







plasma EXCEPT that it lacks 1. Albumin 2. Stuart-Prower factor 3. Antihemophilic factor 4. Hageman factor 47. जठररत म जस ि िोभािाओ िा िन-सा रिार,

दहस टाभमन िॳ मदस िन िॳ भलए उ िरदाuी हॴ?





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47. Which type of cells located in gastric glands is responsible for the release of histamine?

1. Mucous neck cells 2. Enterochromaffin-like cells 3. Chief cells 4. Parietal cells 48. तनब न पादपो प न सिॳ िन अणदओ म सॳ िन-सा





signalling molecule induces hyphal branching of arbuscular mycorrhizal fungi, a pheno-menon that is observed at the initial stages of colonization by these fungi?

1. Salicylic acid 2. Abscisic acid 3. Strigolactones 4. Systemin 49. uदद अधासमण I म अववuोजन घटिा हॴ, तनब न

परर u म अतिसभा uि: िन-सा घटॳगा?




4. दो uद मि सामा u हगॳ ि ा दो n+1 हगॳ। 49. If non-disjunction occurs in meiosis I, which

of the following scenario is most likely to occur?

1. Two gametes will be n+1 and two will be n-1

2. One gamete will be n+1, two will be ‘n’ and one will be n-1

3. Two gametes will be normal and two will be n-1

4. Two gametes will be normal and two will be n+1

50. तनब न म सॳ िन-सा F लाज मड रखनॳवाली

िोभािाओ िॳ भलए सही हॴ?





50. Which of the following is true for cells harbouring F plasmid?

1. Their F plasmid is non-functional. 2. They exhibit increased rates of transfer of


origin of replication is inactivated.

51. घघॳ (Limnaea peregra) िॳ ाख िॳ िद डलीभवन िी ववरासि मािवाी हॴ, uह सदरतिजठि हॴ। दषषणाविा िद डलन रभावी एलील D पर तनभार हॴ ि ा वामाविा िद डलन अरभावी एलील d पर तनभार हॴ।

दषषणाविा (Dd) रिार िी सिान मादा F1 िो नर वामाविा घोघ सॳ रसिररि किuा जािा हॴ। उसिॳ F2 सिान म ववमuद मी: समuद मी uजटu िा अनदपाि स uा होगा?

1. 3:1 2. 1:1 3. 1:3 4. 1:2:1


1. 3:1 2. 1:1 3. 1:3 4. 1:2:1

52. किसी जीन उ पाद म एिल एभमनो अब ल िॳ पररविान म पररणभमि िरनॳ वाला तनब न उ पररविाजन म सॳ िन-सा अतिसभा uि: हॴ?







1. Acridine orange 2. X-rays 3. Ethylmethane sulphonate (EMS) 4. Ethidium bromide 53. तनब न ि न म सॳ िन-सा, जीवन इतिहास


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53. Which one of the following statements

supports the concept of trade-off in the evolution of life history traits?




tion leads to higher population growth 54. जनस uा घन व िॳ फलन िॳ प म dN/dt िा

रॳखातचम रदान िरिा हॴ एि





















56. Which of the following is a correct ranking of

ecosystems based on the root: shoot ratio of plants?





57. तनब न िल प म सॳ िन-सा “म सu िा uदग”

माना जािा हॴ?














recessive at this locus 4. The population is effectively infinite in size

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59. तनब न भवॴञातनि िल प म िन-सा स ितनu िॳ पहलॳ आववभााव सॳ लषझणि हॴ?





1. Tertiary 2. Cretaceous 3. Permian 4. Triassic 60. एि स लोरोक फल a uदस ि ाॴवाल, जजसिा सचuी





4. पीिहररि ाॴवाल वगा 60. An alga having chlorophyll a, floridean starch

as storage product and lacking flagellate cells belongs to the class


नह हॴ?









3. पाररजाति 4. सरजाति

62. Individuals occupying a particular habitat and adapted to it phenotypically but not genotypically are known as

1. Ecophenes. 2. Ecotypes. 3. Ecospecies. 4. Coenospecies. 63. मानव िॳ ECG िो अकिि िरनॳ ववभभ न िार






63. Different leads are used to record ECG of

humans. Which one of the following is NOT unipolar leads?

1. Augmented limb leads 2. V1 and V2 leads 3. Standard limb leads 4. VR and VL leads 64. िोभािाओ म ववाॳ mRNAs िी उपजस ति एव







mRNAs within a cell can be detected by 1. Northern blot analysis 2. RNase protection assay 3. in situ hybridization 4. real-time PCR 65. भलग िॳ बीच रजननीu सफलिा पर अभभतच िा

परस पर ववरोध तनब न सगम िम म किसम राu: नह होगा?





1. Polyandry 2. Monogamy 3. Promiscuity 4. Polygamy

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66. तनब न वव लॳिी ििनीि म किसम रिााीu मापन सजबमभलि नह हॴ?

1. ELISA







1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab 67. Which genes have been introduced in Bollgard II

cotton to get resistance against cotton bollworm, tobacco budworm and pink bollworm?

1. cry1Ab + cry1Ac 2. cry1Ac + cry2Ab 3. cry1Ab + cry2Ab 4. cry9C + cry2Ab 68. एि रादटuॳ िॳ सा पाचन सॳ पवा ि ा प चाि








1. Absorbance at 280 nm 2. Circular dichroism 3. Absorbance at 340 nm 4. Fluorescence value

69. गहरॳ घाव िॳ भलए मानव िो दी जानॳ वाली टॴटानस टीिा हॴ एि

1. DNA टीिा








1. 1200 ि ा 1250

2. 1200 ि ा 1500

3. 1350 ि ा 1500

4. 1250 ि ा 1350

70. The electrospray ionization spectrum of a

mixture of two peptides show peaks with m/z values 301, 401, 501, and 601. The molecular weights of the peptides are

1. 1200 and 1250 2. 1200 and 1500 3. 1350 and 1500 4. 1250 and 1350

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Hkkx \PART 'C'






सभी गलत ि न िा सuोजन चदन: 1. A ि ा B

2. B ि ा C

3. C ि ा D

4. B ि ा D

71. From the following statements,

A. For a reaction to occur spontaneously the free energy change must be negative B. The interaction between two nitrogen molecules in the gaseous state is predominantly electrostatic C. By knowing bond energies, it is possible to deduce whether the bond is covalent bond or hydrogen bond D. Hydrophobic interactions are not important in a folded globular protein


1. A and B 2. B and C 3. C and D 4. B and D 72. समववuदि बदद 6.5 िॳ एि रोटीन, जो िॴ जलाuम सॳ









a protein with an isoelectric point of 6.5 and also binds to calcium. This protein was subjected to four independent treatments: (i) pH 6.4, (ii) 10% glycerol, (iii) 10 mM CaCl2, (iv) 40% ammonium sulphate. This was followed by centrifugation and estimation of the protein in the supernatant. The results are depicted in the graph below:






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73. uरीन िॳ जॴवस लॳण म :










C5 are from Glycine 3. Nl is from Aspartic acid; N3 from

Glutamine side-chain; N9 from N attached to C of Glutamine; N7, C4 and C5 are from Glycine










1. A, B ि ा F

2. B, D ि ा E

3. A, C ि ा D

4. C, E ि ा F 74. From the following statements, A. Hydrogen, Deuterium and Tritium differ in




Helium E. Carbon-14 decays to Nitrogen-14 F. Carbon-14 decays to Carbon-13 pick the combination with ALL correct statements. 1. A, B and F 2. B, D and E 3. A, C and D 4. C, E and F 75. पॳ टाईड-रोटीन सपण िॳ बारॳ म तनब न चार ि न ह:








1. A ि ा B 2. B ि ा C

3. A ि ा D 4. C ि ा D

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75. The following are four statements on peptide/ protein conformation:

A. Glycine has the largest area of conforma- tionally allowed space in the Ramachandran plot of





Choose the combination of correct statements. 1. A and B 2. B and C 3. A and D 4. C and D 76. एि ही करuाधार पर दो अलग ए ाईम, X ि ा Y,









Which of the following statements is correct? 1. Only protein X is specific for the substrate, S 2. Only protein Y is specific for the substrate, S 3. Both X and Y are specific for the substrate, S 4. Both X and Y are non-specific for the substrate, S 77. हररिलवि रिाuा िा सदमि ‘A’ हॴ। ‘A’ िॳ











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78. G1 सॳ S िि िॳ एि िोभािा चर रगमन िॳ दरान

साईस लीन D-CDK4, Rb िा फॉस फोररलीिरण िरिा हॴ ि ा E2F िॳ भलए उसिी बधदिा िो िम िरिा हॴ। Rb सॳ E2F अपघदटि होिा हॴ ि ा S-अवस ा जीन अभभ uजसि िो करuाजवि िरिा हॴ। रोटीन















cells in the following stages of cell cycle: (a) G1 phase, (b) G2 phase, (c) M phase. These cells were then grown in medium containing

tritiated thymidine. Maximal amount of freshly labelled DNA is likely to be obtained in S-phase cells fused with

1. G1 phase cells 2. G2 phase cells 3. M phase cells 4. Both G1 and G2 phase cells 80. वविास िरिॳ E. coli िोभािाओ िॳ सा रतिजॴववि

सॳफालॳजससन िो भमलानॳ पर, िोभािाओ िा ििदलन हो जािा हॴ, िप चाि अपघटन। सॳफा लॳजससन इसिा एि सदमि हॴ






1. protein synthesis 2. DNA synthesis 3. peptidoglycan synthesis 4. RNA polymerase 81. रतिदीजिि: लॳबभलि रोटीन, मीर म रोटीनराव

िॳ अ uuन िॳ भलए उपuोग म भलuा गuा। रतिदीजि तनब न म पाuी गई:





1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a) 81. Fluorescently tagged protein was used to study



sequence in which these events occur? 1. (a) ⟶ (b) ⟶ (c) 2. (b) ⟶ (c) ⟶ (a) 3. (c) ⟶ (a) ⟶ (b) 4. (c) ⟶ (b) ⟶ (a)

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82. uह सदतनजचि िरनॳ िॳ भलए कि माम पणाि: ससातधि पररपस व mRNAs साईटोसॉल िि तनuााि होनॳ अनदमतिि ह, snRNPs िॳ सा सगि Pre -mRNAs












1. B ि ा C 2. A ि ा D








Choose the correct combination of the possible outcomes:

1. B and C 2. A and D 3. B and D 4. A and C 83. टॳलोमॳरॳ, एि रोटीन-RNA सिद ल, िी एि ववभा ट

उ रम राजसर टॳ गतिववतध हॴ जो DNA स लॳण िॳ दरान अ uाा िॳ रतिितिuन िो सपणा िरिी हॴ। uuवप उसिॳ िई गदणधमा DNA पॉभलमरॳ िॳ सा ह, िद ि भभ न भी ह। टॳलोमॳरॳ िॳ तनब न गदणधम म सॳ िन-सा DNA पॉभलमरॳ िॳ गदणधमा सॳ भभ न हॴ?











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85. तनब न तचम म, िीन पररिाल पतनि अनदवाद सदमि

िॳ सा उपचाररि िोभािाओ िा पॉभलसोम पररछ िॳदन दाााuा गuा हॴ। uॳ िीन सदमि ह:









Match the polysome profile to the inhibitor 1. (i) – a; (ii) – b; (iii) – c 2. (i) – b; (ii) – c; (iii) – a 3. (i) – c; (ii) – b; (iii) – a 4. (i) – a; (ii) – c; (iii) – b

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86. स ितनu म, CG रचदर अनदरम सामा uि: C पर मॴत लीिररि होिॳ ह, जो मनीिि जीन िो लॳबल िरनॳ िा एि िरीिा हॴ। uuवप रबधन जीन िॳ उ नाuि राu: CpG वीप िॳ सगि ह, ि ावप वॳ स ितनu म अभभ uस ि होिॳ ह। तनब न म सॳ िन-सा इसिी रॳ ठिम uा uा िरिा हॴ?













87. किसी रuोग म लाल रस ि िोभािाu अप घदटि िी


NaCl िॳ सा गददटिा तनिाली गuी ि ा कफर

100,000g पर अपिरीिरण किuा गuा। अतध लवी म तनबन रोटीन म सॳ िन-सा उपजस ि होगा?

1. बड 3

2. लाईिोफोरीन

3. G रोटीन uदजमि राही

4. स पॴजसरन 87. In an experiment, red blood cells were










88. In order to study the intracellular trafficking of

protein ‘A’, it was tagged with GFP (A-GFP). Fluorescence microscopy showed that A-GFP co-localizes with LAMP1. In the presence of bafilomycin A, an inhibitor of H+-ATPase, A-GFP does not co-localize with LAMP1. Instead, it co-localizes with LC3 puncta. Which one of the following statements is TRUE?



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A B

a. इटॳतरन (i) रस ि सररिा म ववभभ न न वर, िोभािा-िोभािा आसजन अ uो uकरuाओ िो माजuि िरनॳवालॳ लॴजसटन


c. Ig-अतध

िद टद ब

(iii) Ca2+- तनभार रबल होमो-क फभलि िोभािा-िोभािा आसजन िो माजuि िरिा हॴ




A B


b. Cadherin (ii) Contains extracellular Ig-like domains and are mainly involved in the

fine tuning of cell-cell adhesive interactions during development and regeneration.

c. Ig-super- family








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91. राईपनोसोम म, एि 35 षार रॳिा अनदरम िई भभ न अनदलॳख िॳ सा जोाा जािा हॴ, िाuााील mRNAs िो बनािॳ हदuॳ। नॳिा अनदरम अ u RNAs िॳ सा इस वारा जोाा जािा हॴ:









an internal A present in the leader sequence 92. िद ि ववितिजन स िभ A म ि ा स िभ B म रतिरषी

अनदकरuा सॳ बचनॳ िॳ भलए उनसॳ उपuोग म भलए जानॳ वालॳ िद ि अवविीu ररम तनब नवि सचीिि ह:

A B a. Trypanosoma








1. a – (i), b – (ii), c – (iii)

2. a – (ii), b – (iii), c – (i)

3. a – (iii), b – (i), c – (ii)

4. a – (i), b – (iii), c – (ii)


A B

a. Trypanosoma brucei

(i) Capable of employing unusual genetic processes by which they generate extensive variations in their variant surface glycoproteins (VSG)







1. a – (i), b – (ii), c – (iii) 2. a – (ii), b – (iii), c – (i) 3. a – (iii), b – (i), c – (ii) 4. a – (i), b – (iii), c – (ii) 93. दो स टॴराइा हामोन रादहu X ि ा Y म एि सल नी

आबधन षॳम ि ा एि DNA आबधन षॳम उपजस ि ह। पदनuोगज DNA ििनीिी िॳ उपuोग सॳ एि पररवतिाि हाईरा राही H िॴuार किuा जािा हॴ िाकि उसम X िा सल नी आबधन षॳम ि ा Y िा

DNA आब धन षॳम उपजस ि ह। िप चाि रादहu X, Y ि ा H िो अतिअभभ uस ि िरिी िोभािाओ

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िॳ िीन समदछ चu िो अलग सॳ हामोन X uा हामोन Y िॳ सा उपचार किuा गuा। uह मानिॳ हदए कि िोई तिuाि-अभभकरuिा नही हॴ, तनब न आलॳख म सॳ िन-सा, हर ववu म राही-सल नी आबधन िा रॳ ठिम रतितनतध व िरिा हॴ?

93. Two steroid hormone receptors X and Y both

contain a ligand binding domain and a DNA binding domain. Using recombinant DNA technology, a modified hybrid receptor H is prepared such that it contains the ligand binding domain of X and DNA binding domain of Y. Three sets of cells over-expressing receptors X, Y and H were then treated separately either with hormone X or with hormone Y. Assuming that there is no cross-reactivity, which one of the following graphs best represent the receptor-ligand binding in each case?

94. रोटीन Y िॳ सा सिद भलि िरिॳ साईटोसॉल म एि रोटीन X िो सकरu अवस ा म रखा जािा हॴ। किसी रतिबल उ िॳजन िॳ अधीन, Y फॉस फोररभलि हो जािा हॴ, ि ा उसिा रोदटuोसोमल अविा हो जािा हॴ। X मदस ि हो जािा हॴ, िरि म स ानािररि हो जािा हॴ, ि ा एपो टोभसस वारा िोभािा म uद िरनॳवालॳ जीन िॳ अनदलॳखन म पररणभमि होिा हॴ। तनब न चार अलग ववu म रतिबल उ िॳजन ददuा गuा:-






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Which one of the following graphs best

describes the apoptotic state of the cells in the above cases? Y-axis represents % apoptotic cells.

95. समदरी अतचान अड िॳ तनॳचन िॳ दरान घटनॳवाली

तनब न घटनाओ पर ववचार:














Which of the above statement(s) is NOT true? 1. Only C 2. A and C 3. Only D 4. B and D

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96. स िनी रण िॳ वविास िॳ दरान भलuॳ जानॳ वालॳ तनणाu िॳ बारॳ म तनब न ि न ददuॳ गuॳ।

A. आिररि िोभािा र uभार (ICM) िी अनॳिाजसि िीन अनदलॳखन िारि Oct 4, Sox 2

ि ा Nanog िॳ एि रोा सॳ बनाuॳ रखी जािी हॴ।





1. A ि ा B 2. A ि ा C










1. CED-4, Apaf -1 सॳ साब u रखिा हॴ।




for proper formation of different structures. In C. elegans, apoptosis is accentuated by ced-3 and ced-4 genes, which in turn are negatively regulated by ced-9 and eventually EGL-1. When compared to mammals, functionally similar homologues have been identified. Accordingly, which one of the following statements is NOT correct?



िॳ बारॳ म किuॳ गuॳ तनब न ि न म सॳ िन-सा सही नह हॴ ?












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99. उभuचर िॳ ववu म, प ठeu ओ ठ िोभािाu ि ा उनि सजाि “स पॳमन-मानगोल ा uवस ापि” िहलािॳ ह। “ uवस ापि” सॳ सबतधि तनब न ि न किuॳ गuॳ:







1. A ि ा D

2. D ि ा E

3. A ि ा E

4. B ि ा C









िोभािी समदरी अतचान रण िॳ सा जदटल पदनuोजन सजबमभलि ा। uह ववतध साधारणि: अि चमा बनानॳ िॳ भलए भाजuि षॳम म रहिॳ िरि िो अनदमातनि बदह चमा षॳम िॳ अदर अदल-

बदल िरिी ी। uदद िरिीu तनणााuि िा

अलगीिरण घदटि हदआ, पररणभमि रण िो अ uवजस ि होना चादहए। परिद डरuॳा नॳ इन रण सॳ सामा u डडभि पाuॳ। सभा u uा uाu ह:






1. माम A

2. माम D

3. माम A ि ा B

4. A, C ि ा D

100. Driesch performed the famous “pressure plate” experiment involving intricate recombination with an 8-celled sea urchin embryo. This procedure reshuffled the nuclei that normally would have been in the region destined to form endoderm into the presumptive ectoderm region. If segregation of nuclear determinants had occurred, the resulting embryo should have been disordered. However, Driesch obtained normal larvae from these embryos. The possible interpretations regarding the 8-celled sea urchin embryo are:

A. The prospective potency of an isolated blastomere is greater than its actual prospective fate.



D. Regulative development occurs where location of a cell in the embryo determines its fate.

Which of the above interpretation(s) is/are true? 1. Only A 2. Only D 3. Only A and B 4. A, C and D

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1. A, B ि ा C

2. A, C ि ा D

3. A, B ि ा D

4. B, C ि ा D

101. Read the following statements related to plant-

pathogen interaction A. Systemic acquired resistance is observed

following infection by compatible pathogen B. Induced systemic resistance is activated following infection by compatible pathogen C. A bacterial infection can induce effector triggered immunity (ETI) leading to hypersensitive response locally D. NPR1 monomers that are released in cytosol due to salicylic acid accumulation is rapidly translocated to nucleus









1. माम A ि ा C

2. माम B ि ा C

3. माम B ि ा D

4. माम A ि ा B









103. पादपहामोन िॳ नाम स िभ I म ि ा उनसॳ सगि

पहल/रभाव/रिाuा स िभ II म तनब न ददuॳ गuॳ ह

I II A ऑस सीन (i) ववलबि पणा

जीणािा






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I II








































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The reasons for difference in the pattern of alveolar gas exchange of N2O and CO have been proposed in the following statements:






107. पद पाग वविास िॳ रतिमान िो पद प िॳ आस न

चस िर म समापवधी जीन िी uजसिगि एव आछ िाददि अभभ uजसि तनधााररि िरिी हॴ। एि एराबडोजसस उ पररविी म पद पाग तनब नवि बदटि ह:













A. B. C.

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D.


1. A ि ा B 2. B ि ा C

3. C ि ा D 4. A ि ा D



A. B. C. D.


correct? 1. A and B 2. B and C 3. C and D 4. A and D








1. A, B ि ा C

2. B, C ि ा D

3. A, B ि ा D

4. A, C ि ा D











B. पररधीu पणाम uोिि िोभािाओ म फॉस फोईनाल पाईवॳट िॉबााजससलॳस वारा वाuदमडलीu CO2 जस रीिररि हो हॴ, एि चार िॉबान अब ल दॳिॳ हदuॳ।

C. पणाम uोिि िॳ आिररि परि म चार िॉबान अब ल िो NAD-मॴभलि ए ाईम वविॉबााजससली- िरण िरिॳ CO2 िो मदस ि िरिा हॴ।

D. CO2 कफर सॳ पलाछ िद िोभािाओ म िॴ जलवन चर वारा पदन:जस रीिररि होिा हॴ।


1. B, C ि ा D

2. A, B ि ा C

3. A, B ि ा D

4. A, C ि ा D








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111. भमतरि िमिा पर बाu दाब िनॳ िी सवॳदना िी षति िारझणि िरिा हॴ जबकि सापॳषि: ददा सवॳदना अटट रहिा हॴ। उसी िमिा पर स ानीu तन चॳिि



B. स ानीu तन चॳिि वह uासी िमिा रॳखाओ म आवॳग िी चालििा िो िम िरिॳ ह।




1. A ि ा B 2. C ि ा D


111. External pressure given on a mixed nerve

causes loss of touch sensation while pain sensation remains relatively intact. On the other hand, application of local anaesthetics on the same nerve, induces loss of pain sensation keeping touch sensation least affected. These observations can be explained by the following statements:





1. A and B 2. C and D 3. Only C 4. Only D






112. The probable effects of lesion of left optic tract on the vision of a human subject are given below. Identify the correct statement.







2. रतिलोमन ववमuद मी, अ ााि एि रतिभलवप सामा u गदणसम ि ा उसिा समजाि रतिलोमन िॳ सा , ववतनमu िो अनदमि नही िरिॳ स uकि वॳ िदावप uदजमि नही हो सििॳ।



113. Inversions are considered as cross-over

suppressors because 1. Homozygous inversions are lethal and thus

they do not appear in next generation 2. Inversion heterozygotes, i.e., one copy having

normal chromosome and its homologue having inversion, does not allow crossing over to occur as they cannot pair at all



114. िीन met– E. coli उ पररविी रभॳद अलग किuॳ गuॳ।

उ पररविान िॳ स वभाव िॳ अ uuन हॳिद इन उ पररविी रभॳद िा EMS uा रोलॳववनस उ पररविाजन िॳ सा उपचार किuा गuा, ि ा र uावि िॳ भलए अकिि किuा गuा। पररणाम तनब नवि साराभाि ह:

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Mutant strain Mutagen treatment EMS Proflavin

A - + B + - C - -















114. Three met– E. coli mutant strains were isolated. To study the nature of mutation these mutant strains were treated with mutagens EMS or proflavins and scored for revertants. The results obtained are summarized below:


EMS Proflavin A - + B + - C - -




1. A-Transversion B- Insertion or deletion of a single base C- Deletion of multiple bases 2. A-Transition B- Transversion C- Insertion or deletion of a single base 3. A-Insertion or deletion of a single base B- Transition C- Deletion of multiple bases

4. A- Transition B- Insertion or deletion of multiple bases C- Transversion

115. तनब न वाावली किसी ववाॳि िॳ वाागति रतिमान िो दााािी हॴ।

वाागति िी ढग ि ा इसिी रातuििा कि III पीढी

म पदमी वह ववाॳि दाााuॳगी, इनिा अनदमान िीजजuॳ।


3. अभलगसमी अरभावीब रातuििा 1/2 हॴ।



From the following select the possible mode of

inheritance and the probability that the daughter in generation III will show the trait.


116. एि ास u पादप म ऐलील िा एि uदगल बीज आमाप िो तनधााररि िरिा हॴ। मोटी बीज िॳ भलए उ िरदाuी ‘B’ ऐलील िोटी बीज िॳ भलuॳ उ िरदाuी ‘b’ ऐलील सॳ रभावी हॴ। इस परीषण िॳ भलए कि स uा एि पहचातनि रभावी DNA तचनि (5kb बड) बीज आमाप िो तनuमि िरनॳ वालॳ ऐलील िॳ सा सहलजनि हॴ, एि रuोग किuा गuा। दोन ऐलील और DNA तच ह िॳ भलए ववमuद मी एि पादप सॳ एि िोटी बीज पादि जजसम 5kb बड नही uा सा रसिररि किuा गuा। रसिरण रा ि 100 सिान िा वव लॳण DNA तचनि िी उपजस ति ि ा अनदपजस ति िॳ भलए किuा गuा। पररणाम तनब न िाभलिा म अकिि ह:

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22

23

27

28












22

23

27

28




bold seed but is linked to the small seed trait 117. ऐरीनल वल िद ट िॳ ोना लोमॳलोसा म

स टॴराईडजतनि प िो तनब न तचम दााािा हॴ।










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a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -






a b c d 1 + + + + 2 + + + - 3 + - + - 4 - - + -



119. तनब न तचम तनब न ववभभ न समu बददओ पर जॴव

लu िा रतितनतध व िरिा हॴ: SR = सuोदu; N =


ऊपर ददए गए तचम म िनसा समuबि जॴव लu रतितनतध व िरिा/िरिॳ हॴ/ह?

1. तचम B

2. तचम A ि ा C

3. तचम C ि ा D

4. तचम D

119. Following are the plots representing biological

rhythms at different time points depicted as: SR = Sunrise; N = Noon; SS = Sunset; MN = Midnight

Which of the plot(s) represent the ultradian

biological rhythm(s)? 1. Plot B 2. Plots A and C 3. Plots C and D 4. Plot D


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121. Given below is a graphical representation of changes in morphological features over a period of geological time scale, where population A accumulates heritable morphological changes and give rise to a distinct species B. Population B splits into a distinct species B2




1. 81% 2. 49% 3. 42% 4. 18%


1. 81% 2. 49% 3. 42% 4. 18%

123. िीन अलग Hfr रभॳद िॳ उपuोग सॳ अिरातuि

सगम रuोग किuॳ गuॳ। िीन (1 -3) रभॳद वरणीu तचनि िॳ अलग सuोजन रखिॳ ह। तनब न िाभलिा म हर रभॳद िॳ भलए हर तचनि िा रवॳा समu दाााuा गuा हॴ।


(5’) thr (17’)

strr

(25’) phe (30’)

pro (45’)

Hfr #2 strr

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)

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1. met-thr-strr-phe-pro-pur r-his 2. purr-pro-his-met-thr-strr-phe 3. strr-purr-his-met-phe-pro-strr




(5’) thr (17’)

str r

(25’) phe (30’)

pro (45’)

Hfr #2 str r

(15’) pur (28’)

pro (35’)

his (45’)

met (55’)

Hfr #3 pro (2’)

his (12’)

met (22’)

str r

(42’) phe (47’)

Using the above data, predict the correct seque-nce of markers on the E. coli chromosome.

1. met-thr-str r-phe-pro-purr-his 2. pur r-pro-his-met-thr-str r-phe 3. str r-pur r-his-met-phe-pro-str r







124. Peripatus is an interesting living animal having unjointed legs, nephridia, haemocoel, trachea, dorsal tubular heart, claws, jaws, continuous muscle layers in body wall. This is considered as a connecting link between





125. तनब न uवस ा मि तचम आविबीजजu म वविीuि

वविास िा रतितनतध व िरिा हॴ।





125. The following schematic diagram represents secondary growth in the angiosperms.



1. A – Inter-fascicular, B – Fascicular, C – Vascular, D – Cork

2. A – Fascicular, B – Inter-fascicular, C – Vascular, D – Cork

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3. A – Cork, B – Inter-fascicular, C – Fascicular, D – Vascular

4. A – Cork, B – Fascicular, C – Inter- fascicular, D – Vascular

126. तनब न िाभलिा रमदख िविी समह ि ा उनिॳ

लषण िी सची रदान िरिी हॴ:














Which one of the following options represents the appropriate match between the fungal group and their characteristics?


127. एि जॴववॴञातनि होिर आप िीन टॴस सा A, B ि ा C िा वगीिरण िरना चाहिॳ ह। आपिॳ पास िीन ववाॳि p, q ि ा r िॳ बारॳ म सचना हॴ। ववाॳि जो पॴिि हॴ, ‘0’ तगना जािा हॴ ि ा ववाॳि जो uदिप न हॴ, ‘1’ तगना जािा हॴ। िीन टॴस स म पाuॳ गuॳ ववाॳि िा बटन तनब नवि हॴ:

A B C

p 1 1 0 q 1 1 0 r 0 1 1









A B C p 1 1 0 q 1 1 0 r 0 1 1



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रोग









A Bordetella




wheat D Anaplasma


cough in humans


















130. आप uह रॳषण िरिॳ ह कि नाितचमटी िी दो

रजातिuा, रजाति 1 ि ा रजाति 2, अिरा वारीu ाॴल िी रमा: ऊपरी ि ा तनचली परि म तनवास िरिी ह। जब आपसॳ रजाति 2 तनचली परि सॳ तनिाल दी जािी हॴ, िभी रजाति 1 ऊपरी ि ा तनचली, दोन परि म तनवास िर सििी हॴ। इन

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रॳषण सॳ आपिा तन िा तनब न ददuॳ गuॳ वविल प म सॳ स uा होगा?












132. ाीिो ण घासभभमu िॳ सही स ानीu नाम िो अपनॳ भगोलीu पररसर िॳ सा सदमॳभलि िर:











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133. किसी रजाति िॳ भलए पररिजलपि जीवन िाभलिा तनब नवि हॴ:



(nx)


(dx)


(lx)


0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0



Age class (x)

Number alive (nx)

Number dying (dx)

Age specific

survivor-ship (lx)


(mx)

0 – 5 100 50 0.0 5 – 10 50 0.5 0.5

10 – 15 10 0.5 15 – 20 20 10 0.2 1.0 20 – 25 10 1.0














135. रजाति-रचदरिा (X-अष) ि ा समददाu सॳवा (Y-अष)

िॳ बीच सभा u सबध िी uा uा हॳिद रस िाववि ववभभ न पररिल पनाओ िॳ आलॳखीu रतितनतध व तनब नवि ह।





िद जीभाला 4. (a) िीलि, (b) िद जीभाला, (c) अतिररस ििा, (d)


135. Following are the graphical representations of

various hypotheses proposed for explaining the possible relationships between species richness (X-axis) and community services (Y-axis).

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Which of the following options is the correct

match between the graphical representations and the hypotheses?





Idiosyncratic















destruction in proteasomes

Which one of the following combinations of proteins functions inside the plant cells?

1. Only A and C 2. A, B and C 3. Only B and C 4. A, B and D










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Which one of the following statements is correct?

1. CD is more sensitive to structural changes than fluorescence

2. Fluorescence is more sensitive to structural changes than CD

3. Both methods are equally responsive to structural changes

4. Acrylamide alters the secondary structure of the protein

138. पॉभल uजसलuोटाइा ाखलाओ िॳ अफॉस फोररलीिि

5 - भारा िॳ फॉस फोररलीिरण वारा DNA uा RNA







138. Polynucleotide kinase (PNK) is frequently used for radiolabeling DNA or RNA by phosphorylating 5 - end of non-phosphorylated polynucleotide chains. Which of the following statement about PNK is NOT true?




139. T7 RNA पॉभलमरॳ उ नाuि ि ा lac सिारि िॳ अिगाि रोटीन X िॳ भलए िटलॳखन िरिॳ एि जीन िो एि अभभ uजसि सवाहि म स लोतनि किuा गuा। 37C पर 6 घटॳ िॳ भलए 1 mM IPTG िॳ भमलानॳ सॳ िोभािाu रॳररि िी गuी। िोभािाओ िॳ लuन िरिॳ अववलॳu वपड ि ा िोभािा-मदस ि अतध लावी म अपिरीिरण वारा रभाजजि किuॳ गuॳ। अववलॳu वपड म रोटीन X उपजस ि हॴ। (िोभािा-मदस ि अतध लावी) ववलॳu रभाग म रोटीन X िो अभभ uस ि िरनॳ िॳ रu न म नीचॳ ददए गए िन-सी uदिनीति िा आप उपuोग िरगॳ?





139. A gene encoding for protein X was cloned in an

expression vector under the T7 RNA polymerase promoter and lac operator. Cells were induced by the addition of 1 mM IPTG at 37C for 6 h. Cells were lysed and fractionated into insoluble bodies and cell-free supernatant by centrifugation. Protein X is present in the insoluble bodies. Which one of the following strategies would you use to express protein X in the soluble fraction (cell-free supernatant)?







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C. ए ाईम ‘5’ िॳ भलए करuाधार िा पररसीमन पारजीनी पादप म X िी मामा म अनदपािी ववि िॳ

न पाuॳ जानॳ िॳ सभाववि िारण िा उपरोस ि ि न म सॳ िन-सॳ रतितनतध व िर सििॳ ह?











141. िविी रतिरोध िॳ भलए पारजीन ‘A’ रखनॳवालॳ एि एिल रतिभलवप समuद मज पारजीनी पादप िो बाद म लवण-रतिबल दॳनॳ िॳ भलए एि दसरॳ जीन ‘B’ िॳ सा पदन: पािररि किuा गuा। दोन पािरण रuोग म िाम म भलuॳ जानॳ वालॳ वरण तचनि जीन अलग ॳ। पदन: पािरण रuोग सॳ पाuॳ गuॳ पारजीनी पादप िो लवण-रतिबल रतिरोध िॳ भलए परीषषि किuा गuा ि ा सदना-सिरण वारा एिल रतिभलवप घटनाu पहचानी गuी। uॳ एिल रभलभलवप घटनाu स वतनॳतचि ी। सभी पारजीनी पादप म दो T-DNAs (A ि ा B पारजीन िो अिववाजटि) िॳ असलजनि स ान पर समािलन होनॳ पर T1 सिान म लषणरपी अनदपाि हगॳ:





141. A single copy homozygous transgenic plant containing the transgene ‘A’ for fungal resistance was subsequently re-transformed with another gene ‘B’ for conferring resistance to salt-stress. The selection marker genes used for both the transformation experiments were different. Transgenic plants obtained following the re-transformation experiment were screened for salt-stress resistance and single copy events were identified by Southern hybridization. These single copy events were self-pollinated. In the event of the two T-DNAs (containing the A and B transgenes) getting integrated in unlinked locations in all the transgenic plants, the phenotypic ratios among the T1 progeny would be:

1. 3 (Fungal resistant + Salt-stress resistant): 1

(Fungal resistant) 2. 1 (Fungal resistant): 2 (Fungal resistant +

Salt-stress resistant): 1 (Salt-stress resistant) 3. 3 (Salt-stress resistant): 1 (Fungal resistant) 4. 1 (Fungal resistant): 1 (Salt-stress resistant):

1 (Fungal resistant + Salt stress resistant)

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BamHI (H+B) ि ा HindIII plus PstI (H+P) िॳ उपuोग सॳ लाज मड िॳ रतिबधन-पाचन वारा आप सही वव uास िॳ स लोन िॳ भलए परीषण िर रहॳ ह। सवाहि िॳ उतचि राि िा मानतचम तनब न दाााuा गuा हॴ।


ऊपर दाााuॳ गuॳ लाज मा म िन-सा, सही वव uास वालॳ स लोन िा रतितनतध व िरिा हॴ?

1. A 2. B 3. C 4. D


Given below is the pattern following

restriction digestion of plasmid isolated from four independent clones (A, B, C or D).



143. 6129 uजसिu िी एि आबादी म M-N तधर रिार िी बारबाररिा तनब नवि हॴ:









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before divergence of vertebrates 3. Exon shuffling exclusively produced such

cluster 4. Whole genome duplications could lead to

such observations

145. किसी झिल ली म अणदओ िॳ ववसरण िॳ आिलन िॳ भलए एि ववतध हॴ रिाा-ववरजन िॳ उपराि रतिदीजि पदन:राजि (FRAP) हॴ। ऐसॳ रति दीजिि: लॳबभलि अणद




iv. झिल ली िी सिह िॳ सा बतधि होनॳवाला एि तचजनि रोटीन





145. Fluorescence recovery after photobleaching

(FRAP) is a method to estimate the diffusion of molecules in a membrane. Fluorescently labelled molecules such as





coefficients. The following data were obtained:


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JOINT CSIR-UGC-JRF/NET DECEMBER 2016 FINAL ANSWER KEY BOOKLET A

LIFE SCIENCE ENGLISH AND BILINGUAL

Set A Key

1 4

2 3

3 1

4 4

5 1

6 1

7 2

8 2

9 1

10 3

11 4

12 3

13 3

14 2

15 2

16 1

17 2

18 1

19 1

20 4

21 2

22 3

23 2

24 4

25 2

26 4

27 2

28 2

29 4

30 2

31 1

32 3

33 4

34 3

35 3

36 2

37 3

38 3

39 2

40 2

41 2

42 2

43 1

44 3

45 3

46 4

47 2

48 2

49 1

50 3

51 *

52 3

53 3

54 3

55 1

56 3

57 4

58 2

59 4

60 1

61 3

62 4

63 2

64 4

65 2

66 3

67 3

68 4

69 2

70 2

71 2

72 4

73 3

74 4

75 2

76 3

77 4

78 2

79 3

80 2

81 1

82 3

83 3

84 1

85 1

86 3

87 3

88 1

89 2

90 1

91 3

92 1

93 4

94 3

95 4

96 1

97 4

98 *

99 1

100 4

101 1

102 2

103 3

104 3

105 2

106 4

107 3

108 4

109 4

110 4

111 1

112 2

113 2

114 4

115 1

116 3

117 2

118 3

119 *

120 2

121 3

122 2

123 4

124 1

125 4

126 1

127 2

128 2

129 3

130 3

131 3

132 2

133 1

134 3

135 3

136 1

137 3

138 2

139 4

140 2

141 1

142 2

143 4

144 1

145 3

change in key indicated in bold

*benefit of marks to those who attempted

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JOINT CSIR-UGC-JRF/NET DECEMBER 2016 FINAL ANSWER KEY BOOKLET B


Set B Key

1 1

2 4

3 1

4 1

5 2

6 4

7 3

8 3

9 4

10 3

11 3

12 2

13 2

14 1

15 2

16 1

17 1

18 4

19 2

20 1

21 3

22 4

23 3

24 3

25 2

26 2

27 3

28 2

29 4

30 2

31 4

32 2

33 2

34 4

35 2

36 1

37 2

38 2

39 2

40 1

41 3

42 3

43 2

44 4

45 2

46 3

47 2

48 3

49 3

50 1

51 3

52 *

53 4

54 2

55 4

56 1

57 3

58 4

59 3

60 3

61 1

62 3

63 4

64 2

65 2

66 2

67 4

68 2

69 3

70 3

71 3

72 3

73 2

74 2

75 4

76 4

77 3

78 3

79 1

80 4

81 2

82 3

83 2

84 1

85 3

86 1

87 1

88 3

89 4

90 3

91 4

92 1

93 4

94 *

95 1

96 4

97 2

98 1

99 3

100 1

101 4

102 4

103 1

104 2

105 1

106 2

107 3

108 3

109 2

110 4

111 3

112 4

113 2

114 4

115 3

116 3

117 2

118 1

119 4

120 1

121 2

122 2

123 3

124 3

125 3

126 2

127 1

128 3

129 3

130 *

131 2

132 3

133 2

134 4

135 1

136 2

137 1

138 2

139 4

140 1

141 3

142 1

143 3

144 2

145 4



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JOINT CSIR-UGC-JRF/NET DECEMBER 2016 FINAL ANSWER KEY BOOKLET C


Set C Key

1 1

2 2

3 4

4 3

5 1

6 4

7 1

8 3

9 2

10 2

11 1

12 3

13 4

14 3

15 1

16 4

17 2

18 1

19 2

20 1

21 2

22 1

23 3

24 4

25 3

26 3

27 2

28 4

29 2

30 4

31 2

32 3

33 2

34 2

35 2

36 4

37 2

38 3

39 3

40 2

41 1

42 2

43 2

44 2

45 4

46 3

47 2

48 3

49 1

50 3

51 *

52 3

53 3

54 4

55 2

56 4

57 1

58 3

59 4

60 3

61 3

62 1

63 3

64 3

65 2

66 4

67 2

68 2

69 4

70 2

71 4

72 4

73 2

74 2

75 3

76 3

77 3

78 2

79 1

80 3

81 3

82 1

83 3

84 1

85 1

86 3

87 4

88 2

89 4

90 3

91 2

92 1

93 3

94 1

95 *

96 1

97 4

98 4

99 1

100 4

101 2

102 4

103 3

104 4

105 4

106 4

107 1

108 2

109 3

110 3

111 1

112 2

113 4

114 3

115 3

116 1

117 2

118 2

119 2

120 1

121 3

122 3

123 *

124 2

125 3

126 2

127 4

128 1

129 4

130 1

131 2

132 2

133 3

134 3

135 3

136 4

137 2

138 1

139 2

140 4

141 1

142 3

143 1

144 3

145 2



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