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Reactions 1086 - 28 Jan 2006 S Bupivacaine Cauda equina syndrome in an elderly patient: case report A 72-year-old man developed cauda equina syndrome after receiving intrathecal anaesthesia with bupivacaine. The man, who was undergoing elective inguinal hernia repair, received a spinal injection of 0.5% hyperbaric bupivacaine 12.5mg [Marcaine]. The 90-minute surgical procedure was uneventful, but, the following morning, he experienced defecation difficulties, and complained of urinary retention, which required catheterisation, and impaired ambulation. On neurological examination, he had impaired sensation to pinprick in both L5 dermatomes, in the perineal region, and on the posterior part of his left calf. He also had diminished reflexes in his knee and ankle joints, compared with his upper limb reflexes. A Lasegue’s test was negative. He had bilateral steppage gait resulting from foot-drop. MRI showed he had no spinal stenosis or compression on the cauda equina nerve roots. He was diagnosed with cauda equina syndrome. One-month postoperatively, he had normal bowel function, and could void normally. He continued to have complaints of painful dysesthesia in the right L5 dermatome, and an intermittent aching pain in his right first toe, and he could still not walk properly. One-month, postoperative electromyography, showed varying degrees of bilateral denervation and reinnervation in the S1, L4 and L5 roots. Two years postoperatively, he still experienced paraesthesia in the dorsal part of his right foot. He also had sleep-altering, nocturnal aching cramps with involuntary extension of his right first toe, and a moderate steppage gait, which impaired his walking. [Treatment given not stated]. Author comment: "Bupivacaine neurotoxicity is suggested by the absence of any other identifiable cause for this neurologic deficit." Chabbouh T, et al. Persistent cauda equina syndrome with no identifiable facilitating condition after an uneventful single spinal administration of 0.5% hyperbaric bupivacaine. Anesthesia and Analgesia 101: 1847-1848, No. 6, Dec 2005 - France 801029695 1 Reactions 28 Jan 2006 No. 1086 0114-9954/10/1086-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Page 1: Bupivacaine

Reactions 1086 - 28 Jan 2006

SBupivacaine

Cauda equina syndrome in an elderly patient: casereport

A 72-year-old man developed cauda equina syndrome afterreceiving intrathecal anaesthesia with bupivacaine.

The man, who was undergoing elective inguinal herniarepair, received a spinal injection of 0.5% hyperbaricbupivacaine 12.5mg [Marcaine]. The 90-minute surgicalprocedure was uneventful, but, the following morning, heexperienced defecation difficulties, and complained of urinaryretention, which required catheterisation, and impairedambulation. On neurological examination, he had impairedsensation to pinprick in both L5 dermatomes, in the perinealregion, and on the posterior part of his left calf. He also haddiminished reflexes in his knee and ankle joints, comparedwith his upper limb reflexes. A Lasegue’s test was negative. Hehad bilateral steppage gait resulting from foot-drop. MRIshowed he had no spinal stenosis or compression on thecauda equina nerve roots. He was diagnosed with caudaequina syndrome. One-month postoperatively, he had normalbowel function, and could void normally. He continued tohave complaints of painful dysesthesia in the right L5dermatome, and an intermittent aching pain in his right firsttoe, and he could still not walk properly. One-month,postoperative electromyography, showed varying degrees ofbilateral denervation and reinnervation in the S1, L4 and L5roots. Two years postoperatively, he still experiencedparaesthesia in the dorsal part of his right foot. He also hadsleep-altering, nocturnal aching cramps with involuntaryextension of his right first toe, and a moderate steppage gait,which impaired his walking.

[Treatment given not stated].Author comment: "Bupivacaine neurotoxicity is suggested

by the absence of any other identifiable cause for thisneurologic deficit."Chabbouh T, et al. Persistent cauda equina syndrome with no identifiablefacilitating condition after an uneventful single spinal administration of 0.5%hyperbaric bupivacaine. Anesthesia and Analgesia 101: 1847-1848, No. 6, Dec2005 - France 801029695

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Reactions 28 Jan 2006 No. 10860114-9954/10/1086-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved