bupivacaine/fentanyl

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Reactions 1225 - 25 Oct 2008 S Bupivacaine/fentanyl Subdural haematoma after spinal anaesthesia: case report A 31-year-old primiparous woman developed subdural haematoma after receiving spinal anaesthesia with bupivacaine and fentanyl. The woman, who had presented for an elective caesarian delivery, received 2mL of 0.5% bupivacaine and 10µg of fentanyl at L3-L4 interspace with a 25-gauge needle. During surgery, she received oxytocin. Her vital signs remained normal throughout the perioperative period. However, 48 hours after surgery, she developed moderate and persistent right headache along with right retro-orbital pain. The woman’s pain did not improve after treatment with nonsteroidal anti-inflammatories and, 2 hours later, she developed drowsiness and a progressive decrease in her consciousness level. Her Glasgow Coma Scale (GCS) score was 8. She had marked right hemiplegia and anisocoria. A CT scan revealed a right temporoparietal subdural haematoma with midline displacement and mass effect. She subsequently underwent a right frontotemporal craniotomy and haematoma was evacuated; surgery was performed under general anaesthesia with fentanyl, propofol and suxamethonium chloride [succinylcholine chloride] induction, and propofol, cisatracurium besilate and remifentanil maintenance. After two days, she was extubated. A neurological examination revealed a GCS score of 15 along with right lower extremity paresis and cranial nerve III paralysis. She was subsequently discharged with minimal weakness of the right lower extremity. Ramos-Aparici R, et al. Acute subdural hematoma after spinal anesthesia in an obstetric patient. Journal of Clinical Anesthesia 20: 376-378, No. 5, Aug 2008 - Spain 801124271 1 Reactions 25 Oct 2008 No. 1225 0114-9954/10/1225-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Page 1: Bupivacaine/fentanyl

Reactions 1225 - 25 Oct 2008

SBupivacaine/fentanyl

Subdural haematoma after spinal anaesthesia: casereport

A 31-year-old primiparous woman developed subduralhaematoma after receiving spinal anaesthesia withbupivacaine and fentanyl.

The woman, who had presented for an elective caesariandelivery, received 2mL of 0.5% bupivacaine and 10µg offentanyl at L3-L4 interspace with a 25-gauge needle. Duringsurgery, she received oxytocin. Her vital signs remainednormal throughout the perioperative period. However,48 hours after surgery, she developed moderate and persistentright headache along with right retro-orbital pain.

The woman’s pain did not improve after treatment withnonsteroidal anti-inflammatories and, 2 hours later, shedeveloped drowsiness and a progressive decrease in herconsciousness level. Her Glasgow Coma Scale (GCS) scorewas 8. She had marked right hemiplegia and anisocoria. ACT scan revealed a right temporoparietal subdural haematomawith midline displacement and mass effect. She subsequentlyunderwent a right frontotemporal craniotomy and haematomawas evacuated; surgery was performed under generalanaesthesia with fentanyl, propofol and suxamethoniumchloride [succinylcholine chloride] induction, and propofol,cisatracurium besilate and remifentanil maintenance. After twodays, she was extubated. A neurological examination revealeda GCS score of 15 along with right lower extremity paresis andcranial nerve III paralysis. She was subsequently dischargedwith minimal weakness of the right lower extremity.Ramos-Aparici R, et al. Acute subdural hematoma after spinal anesthesia in anobstetric patient. Journal of Clinical Anesthesia 20: 376-378, No. 5, Aug 2008 -Spain 801124271

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Reactions 25 Oct 2008 No. 12250114-9954/10/1225-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved