Reactions 915 - 17 Aug 2002

Citalopram

Hyponatraemia in an elderly patient: case reportAn elderly man [age not stated] developed hyponatraemia

while receiving citalopram for anxiety and depression.The man developed visual hallucinations, paranoid

delusions, forgetfulness, agitation, and suicidal and homicidalideation subsequent to starting treatment with citalopram10mg once daily [duration of treatment not stated]. He hadstopped taking citalopram several days before presentation.He was admitted to hospital and laboratory investigationsrevealed serum and urinary sodium levels of 131 mmol/L each,and serum and urinary osmolalities of 275 and 460 mOsm/kg,respectively.

Three days after admission the man’s serum sodium levelhad increased to 134 mmol/L and he was diagnosed withdelirium secondary to hyponatraemia. This subsequentlyresolved and dementia was ruled out.Bourgeois JA, et al. A case of SIADH and hyponatremia associated withcitalopram. Psychosomatics 43: 241-242, May-Jun 2002 - USA 807209682

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Reactions 17 Aug 2002 No. 9150114-9954/10/0915-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved