Reactions 1514, p28 - 16 Aug 2014

Lercanidipine/enalapril

Dry cough: case reportAn observational study of 186 patients identified a patient

[age and sex not stated] experiencing dry cough followingtherapy with lercanidipine/enalapril [route, dosage andduration of therapy to reaction onset not stated]. The patientwith a history of hypertension was initiated on lercanidipine/enalapril (10mg/20mg). Subsequently, the patient experiencedpersistent dry cough [outcome not stated].

Author comment: "The objective of the study was toassess the efficacy and safety of a Lecarnidipine-EnalaprilFixed-Dose Combination (FDC) for the treatment ofHypertension (HT)." "Adverse effects were seen in only onepatient (0.5%) referring persistent dry cough."Joao M, et al. Efficacy and safety of a lecarnidipine-enalapril fixed-dosecombination in hypertensive patients. Journal of Clinical Hypertension 15 (Suppl.1): 167, May 2013. Available from: URL: http://www.ashabstracts.com/abstract.asp?MeetingID=797&id=106003 [abstract] - Portugal 803106948

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Reactions 16 Aug 2014 No. 15140114-9954/14/1514-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved