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Reactions 1255 - 6 Jun 2009 S Bupivacaine Phantom limb pain during spinal anaesthesia in an elderly amputee: case report For two consecutive surgeries, a 68-year-old amputee experienced phantom limb pain during spinal anaesthesia with bupivacaine; on both occasions, he was treated effectively with midazolam. The man, who had peripheral artery occlusive disorder and had undergone below-knee amputation of his right leg 10 years earlier, presented for below-knee amputation of his left leg. Spinal anaesthesia was induced at the L3-4 interspace with bupivacaine 10mg, and he was placed in the supine position and preparation for surgery was started. Ten minutes later, he reported continuous, severe tingling and burning sensations in his right stump; he had a pain intensity of 10 according to the visual analogue scale. Tests revealed loss of sensation to cold up to the T10 level, and he could not move his legs. The man received IV midazolam 3mg, but his pain was not completely relieved. He then received a further 2mg of midazolam and became sedated. When he woke approximately 15 minutes after receiving the second midazolam dose, the phantom limb pain had resolved, and did not recur. Three weeks later, the man underwent surgery for debridement of the left stump. Again, he received spinal anaesthesia with bupivacaine 10mg. However, 10 minutes after receiving the drug, the phantom limb pain in his right leg returned; the pain intensity was half as severe as on the previous occasion. He received midazolam 3mg, with pain relief. At follow-up on postoperative day 2, there was no recurrence of phantom limb pain. Su C-J, et al. Midazolam as an effective drug for severe phantom limb pain in a patient after undergoing spinal anesthesia for two consecutive surgeries in the contralateral lower limb. Acta Anaesthesiologica Taiwanica 47: 32-35, No. 1, Mar 2009 - Taiwan 801141758 1 Reactions 6 Jun 2009 No. 1255 0114-9954/10/1255-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved

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Page 1: Bupivacaine

Reactions 1255 - 6 Jun 2009

SBupivacaine

Phantom limb pain during spinal anaesthesia inan elderly amputee: case report

For two consecutive surgeries, a 68-year-old amputeeexperienced phantom limb pain during spinal anaesthesiawith bupivacaine; on both occasions, he was treatedeffectively with midazolam.

The man, who had peripheral artery occlusive disorderand had undergone below-knee amputation of his right leg10 years earlier, presented for below-knee amputation ofhis left leg. Spinal anaesthesia was induced at theL3-4 interspace with bupivacaine 10mg, and he was placedin the supine position and preparation for surgery wasstarted. Ten minutes later, he reported continuous, severetingling and burning sensations in his right stump; he had apain intensity of 10 according to the visual analogue scale.Tests revealed loss of sensation to cold up to the T10 level,and he could not move his legs.

The man received IV midazolam 3mg, but his pain wasnot completely relieved. He then received a further 2mg ofmidazolam and became sedated. When he wokeapproximately 15 minutes after receiving the secondmidazolam dose, the phantom limb pain had resolved, anddid not recur.

Three weeks later, the man underwent surgery fordebridement of the left stump. Again, he received spinalanaesthesia with bupivacaine 10mg. However, 10 minutesafter receiving the drug, the phantom limb pain in his rightleg returned; the pain intensity was half as severe as on theprevious occasion. He received midazolam 3mg, with painrelief. At follow-up on postoperative day 2, there was norecurrence of phantom limb pain.Su C-J, et al. Midazolam as an effective drug for severe phantom limb pain in apatient after undergoing spinal anesthesia for two consecutive surgeries in thecontralateral lower limb. Acta Anaesthesiologica Taiwanica 47: 32-35, No. 1, Mar2009 - Taiwan 801141758

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Reactions 6 Jun 2009 No. 12550114-9954/10/1255-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved