Reactions 384 - 18 Jan 1992

Theophylline

Asthma with a sustained-release preparation: casereport

Shortly after beginning sustained-release theophylline(’Theodur’) therapy to treat dyspnoeic attacks, a 38-year-oldman presented with dyspnoea, chest tightness and dizziness.Oral theophylline challenge had no effect, but ’Theodur’administration resulted in asthma.

A vehicle or preservative, present in the ’Theodur’preparation, was the suspected cause of this reactionSuenaga N, et al. A case of sustained-release theophylline (Theodur Rm)-inducedasthma. Nippon Kyobu Shikkan Gakkai Zasshi 29: 1495-1498, Nov 1991 -Japan 800112437

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Reactions 18 Jan 1992 No. 3840114-9954/10/0384-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved