Reactions 1355 - 11 Jun 2011

SRopivacaine

Local anaesthetic systemic toxicity in an elderlypatient treated with SMOFlipid: case report

A 74-year-old man was scheduled for carotidendarterectomy. He received a modified ultrasound-guidedinterscalene block with perivascular ropivacaine 8mL(3 mg/mL), and developed local anaesthetic systemictoxicity. Immediately after administration, his bloodpressure and heart rate increased, and he had a grand malconvulsion. He was intubated and ventilated, and receivedpropofol, fentanyl, suxamethonium chloride and 500mL of20% SMOFlipid (soya oil/medium chain triglycerides/oliveoil/fish oil). A CT scan of his head showed no injury, and herecovered fully.Heller AR, et al. Local anesthetic systemic toxicity-concept: Inclusion of omega-3fatty acids may reduce adverse effects. Regional Anesthesia and Pain Medicine 36:309-310, No. 3, May-Jun 2011. Available from: URL: http://dx.doi.org/10.1097/aap.0b013e318217aa9a - Germany 803055458

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Reactions 11 Jun 2011 No. 13550114-9954/10/1355-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved