Reactions 1402 - 19 May 2012

SRopivacaine

Grand mal convulsions: case reportA 24-year-old man, who was undergoing surgical

management for a deep wound, received 30mL ofropivacaine 0.75%, injected over 1 minute in 3–4mLincrements, into his psoas muscle to anaesthetise thelumbal plexus. Thirty-nine seconds later, he developed agrand mal convulsion and became apnoeic with extremesalivation and lost consciousness. He underwent lungventilation and received midazolam and pentothal. Hisseizures stopped after 20 seconds and spontaneousrespiration returned. His operation was continued and herecovered with no further complications. The next day, aneurological examination did not reveal any abnormalities.

Author comment: "We hypothesized that an intravascularinjection of local anesthetic in this high dose produced thisunwanted phenomenon."Noulas N, et al. Convulsions after Ropivacaine infusion 225 mg for PsoasCompartment Block. 15th World Congress of Anaesthesiologists : abstr. 481.00, 25Mar 2012. Available from: URL: http://www.wca2012.com - Greece 803070725

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Reactions 19 May 2012 No. 14020114-9954/10/1402-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved